scholarly journals Optimization of a liquid chromatography-tandem mass spectrometry method for the quantification of traces of taxanes in a Corylus avellana cell suspension medium

RSC Advances ◽  
2015 ◽  
Vol 5 (23) ◽  
pp. 17976-17983 ◽  
Author(s):  
Ana Gallego ◽  
Olga Jáuregui ◽  
Elisabeth Moyano ◽  
Javier Palazón ◽  
Isidre Casals ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Cell Suspension ◽  
Corylus Avellana ◽  
Tandem Mass ◽  
Spectrometry Method ◽  
Chromatography Tandem Mass Spectrometry ◽  
Suspension Medium ◽  
Liquid Chromatography Tandem Mass ◽  
Commercially Important

We developed a reliable HPLC-MS/MS method to quantify five of the most commercially important taxanes in a C. avellana cell suspension medium. Its linearity, intra- and inter-day precision, recovery, accuracy, LOD/LOQ and matrix effect were evaluated.

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