Supramolecular glycopolymers with thermo-responsive self-assembly and lectin binding

2015 ◽  
Vol 6 (37) ◽  
pp. 6623-6631 ◽  
Author(s):  
Nese Cakir ◽  
Gurkan Hizal ◽  
C. Remzi Becer
Keyword(s):  
Molecular Recognition ◽  
Self Assembly ◽  
Lectin Binding ◽  
Recognition Pattern ◽  
Synthetic Macromolecules ◽  
Key Residues

Incorporating monomers into sequence-defined synthetic macromolecules endows them to mimic nature which results in key residues being anchored in the molecular recognition pattern.

Self-Assembly of Selenium-Bridged Rhenium(I)-Based Metalla Rectangles: Synthesis, Characterization, and Molecular Recognition Studies

2014 ◽  
Vol 33 (2) ◽  
pp. 465-472 ◽  
Author(s):  
Bala. Manimaran ◽  
A. Vanitha ◽  
M. Karthikeyan ◽  
Buthanapalli Ramakrishna ◽  
Shaikh M. Mobin
Keyword(s):  
Molecular Recognition ◽  
Self Assembly

scholarly journals The macroscopic shape of assemblies formed from microparticles based on host–guest interaction dependent on the guest content

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Takahiro Itami ◽  
Akihito Hashidzume ◽  
Yuri Kamon ◽  
Hiroyasu Yamaguchi ◽  
Akira Harada
Keyword(s):  
Molecular Recognition ◽  
Smart Materials ◽  
Self Assembly ◽  
Early Stage ◽  
Contact Point ◽  
Sodium Acrylate ◽  
Contact Points ◽  
Assembly Behavior ◽  
Small Clusters ◽  
Macroscopic Shape

AbstractBiological macroscopic assemblies have inspired researchers to utilize molecular recognition to develop smart materials in these decades. Recently, macroscopic self-assemblies based on molecular recognition have been realized using millimeter-scale hydrogel pieces possessing molecular recognition moieties. During the study on macroscopic self-assembly based on molecular recognition, we noticed that the shape of assemblies might be dependent on the host–guest pair. In this study, we were thus motivated to study the macroscopic shape of assemblies formed through host–guest interaction. We modified crosslinked poly(sodium acrylate) microparticles, i.e., superabsorbent polymer (SAP) microparticles, with β-cyclodextrin (βCD) and adamantyl (Ad) residues (βCD(x)-SAP and Ad(y)-SAP microparticles, respectively, where x and y denote the mol% contents of βCD and Ad residues). Then, we studied the self-assembly behavior of βCD(x)-SAP and Ad(y)-SAP microparticles through the complexation of βCD with Ad residues. There was a threshold of the βCD content in βCD(x)-SAP microparticles for assembly formation between x = 22.3 and 26.7. On the other hand, the shape of assemblies was dependent on the Ad content, y; More elongated assemblies were formed at a higher y. This may be because, at a higher y, small clusters formed in an early stage can stick together even upon collisions at a single contact point to form elongated aggregates, whereas, at a smaller y, small clusters stick together only upon collisions at multiple contact points to give rather circular assemblies. On the basis of these observations, the shape of assembly formed from microparticles can be controlled by varying y.

ALLERGY TO DERMATOPHAGOIDES PTERONYSSINUS. MOLECULAR RECOGNITION PATTERN ATTRIBUTED TO DIFFERENT PATHOLOGIES

2021 ◽  
Vol 147 (2) ◽  
pp. AB131
Author(s):  
Fernando Pineda de la Losa ◽  
Ruperto González-Pérez ◽  
Miriam Castillo ◽  
Paloma Poza-Guedes ◽  
E. Mederos-Luis ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Dermatophagoides Pteronyssinus ◽  
Recognition Pattern

Structural models for the self-assembly and microtubule interactions of gamma-, delta- and epsilon-tubulin

2001 ◽  
Vol 114 (2) ◽  
pp. 413-422 ◽  
Author(s):  
Y.F. Inclan ◽  
E. Nogales
Keyword(s):  
Self Assembly ◽  
Structural Models ◽  
Dependent Manner ◽  
Gamma Delta ◽  
Sequence Comparisons ◽  
Alpha Tubulin ◽  
A Cell ◽  
Gamma Tubulin ◽  
Cycle Dependent ◽  
Key Residues

alphabeta-tubulin heterodimers self-assemble to form microtubules nucleated by gamma-tubulin in the cell. Gamma-tubulin is believed to recruit the alphabeta-tubulin dimers that form the minus ends of microtubules, but the molecular mechanism of this action remains a matter of heated controversy. Still less is known about the function and molecular interactions of delta-tubulin and epsilon-tubulin. delta-tubulin may seed the formation of the C triplet tubules in the basal bodies of Chlamydomonas and epsilon-tubulin is known to localize to the centrosome in a cell cycle-dependent manner. Using the structure of alphabeta tubulin as a model, we have analyzed the sequences of gamma-, delta- and epsilon-tubulin in regions corresponding to different polymerization interfaces in the tubulin alphabeta dimer. The sequence comparisons sometimes show clear conservation, pointing to similar types of contacts being functionally important for the new tubulin considered. Conversely, certain surfaces show marked differences that rule out equivalent interactions for non-microtubular tubulins. This sequence/structure analysis has led us to structural models of how these special tubulins may be involved in protein-protein contacts that affect microtubule self-assembly. delta-tubulin most likely interacts longitudinally with alpha-tubulin at the minus ends of microtubules, while epsilon-tubulin most likely binds to the plus end of beta-tubulin. Conservation of key residues in gamma-tubulin suggests that it is capable of longitudinal self-assembly. The implications for the protofilament and template models of nucleation are considered.

Self-Assembly and Molecular Recognition in Water: Tubular Stacking and Guest-Templated Discrete Assembly of Water-Soluble, Shape-Persistent Macrocycles

2020 ◽  
Vol 142 (6) ◽  
pp. 2915-2924 ◽  
Author(s):  
Qiuhua Wang ◽  
Yulong Zhong ◽  
Daniel P. Miller ◽  
Xiaoxing Lu ◽  
Quan Tang ◽  
...  
Keyword(s):  
Molecular Recognition ◽  
Self Assembly ◽  
Water Soluble

A dual redox-responsive supramolecular amphiphile fabricated by selenium-containing pillar[6]arene-based molecular recognition

2018 ◽  
Vol 54 (91) ◽  
pp. 12856-12859 ◽  
Author(s):  
Yujuan Zhou ◽  
Kecheng Jie ◽  
Feihe Huang
Keyword(s):  
Molecular Recognition ◽  
Self Assembly ◽  
The Self ◽  
Redox Responsive ◽  
Assembly Behavior

A dual redox-responsive pillar[6]arene-based supramolecular amphiphile was fabricated in water. The self-assembly behavior of this supramolecular amphiphile in response to dual redox stimuli was investigated.

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