d-Glucosamine as a novel chiral auxiliary for the stereoselective synthesis of P-stereogenic phosphine oxides

2015 ◽  
Vol 13 (34) ◽  
pp. 9029-9034 ◽  
Author(s):  
A. D'Onofrio ◽  
L. Copey ◽  
L. Jean-Gérard ◽  
C. Goux-Henry ◽  
G. Pilet ◽  
...  
Keyword(s):  
Stereoselective Synthesis ◽  
Chiral Auxiliary ◽  
Phosphine Oxides ◽  
Key Steps

A novel use of d-glucosamine as chiral auxiliary for the stereoselective synthesis of phosphine oxides was developed. The three key steps of the process occurred in a stereoselective fashion.

Concise Total Synthesis of Curvulone B

Synlett ◽  
2020 ◽  
Author(s):  
Debendra K. Mohapatra ◽  
Shivalal Banoth ◽  
Utkal Mani Choudhury ◽  
Kanakaraju Marumudi ◽  
Ajit C. Kunwar
Keyword(s):  
Total Synthesis ◽  
Stereoselective Synthesis ◽  
Ring System ◽  
Bond Forming ◽  
Cross Metathesis ◽  
Bond Forming Reactions ◽  
Key Steps

AbstractA concise and convergent stereoselective synthesis of curvulone B is described. The synthesis utilized a tandem isomerization followed by C–O and C–C bond-forming reactions following Mukaiyama-type aldol conditions for the construction of the trans-2,6-disubstituted dihydropyran ring system as the key steps. Other important features of this synthesis are a cross-metathesis, epimerization, and Friedel–Crafts acylation.

scholarly journals A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone via ring-closing metathesis

2009 ◽  
Vol 5 ◽  
Author(s):  
Palakodety Radha Krishna ◽  
Krishnarao Lopinti ◽  
K L N Reddy
Keyword(s):  
Stereoselective Synthesis ◽  
Metathesis Reaction ◽  
Ring Closing Metathesis ◽  
Propargylic Alcohol ◽  
Key Steps

A short stereoselective synthesis of (+)-(6R,2′S)-cryptocaryalactone was successfully completed. Key steps included the application of Carreira’s asymmetric alkynylation reaction to form a propargylic alcohol and subsequently lactone formation using the powerful ring-closing metathesis reaction.

Stereoselective synthesis of β-lactams by condensation of titanium enolates of 2-pyridyl thioesters with imines bearing a chiral auxiliary

Tetrahedron ◽  
1994 ◽  
Vol 50 (31) ◽  
pp. 9471-9486 ◽  
Author(s):  
Rita Annunziata ◽  
Maurizio Benaglia ◽  
Mauro Cinquini ◽  
Franco Cozzi ◽  
Laura Raimondi
Keyword(s):  
Stereoselective Synthesis ◽  
Chiral Auxiliary ◽  
Titanium Enolates

Experimental and Theoretical Investigations of the Stereoselective Synthesis of P-Stereogenic Phosphine Oxides

2015 ◽  
Vol 21 (25) ◽  
pp. 9057-9061 ◽  
Author(s):  
Laurent Copey ◽  
Ludivine Jean-Gérard ◽  
Eric Framery ◽  
Guillaume Pilet ◽  
Vincent Robert ◽  
...  
Keyword(s):  
Stereoselective Synthesis ◽  
Phosphine Oxides ◽  
Theoretical Investigations

Total synthesis of haliclamide

2016 ◽  
Vol 14 (39) ◽  
pp. 9287-9293 ◽  
Author(s):  
Suraksha Gahalawat ◽  
Satyendra Kumar Pandey
Keyword(s):  
Total Synthesis ◽  
Stereoselective Synthesis ◽  
Steglich Esterification ◽  
Key Steps

A stereoselective synthesis of haliclamide has been developed. The synthesis includes MacMillan cross aldol, Mitsunobu inversion, Yamaguchi–Hirao alkylation, Steglich esterification and macrolactamization reactions and the Corey–Fuchs protocol as the key steps.

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