2-Oxo promoted hydrophosphonylation & aerobic intramolecular nucleophilic displacement reaction

2015 ◽  
Vol 13 (32) ◽  
pp. 8637-8641 ◽  
Author(s):  
Satyanarayana Battula ◽  
Narsaiah Battini ◽  
Deepika Singh ◽  
Qazi Naveed Ahmed
Keyword(s):  
Displacement Reaction ◽  
Efficient Catalyst ◽  
Catalyst Free ◽  
Highly Efficient ◽  
Nucleophilic Displacement ◽  
Key Factor ◽  
First Time

Highly efficient catalyst free methods for the synthesis of α-hydroxy-β-oxo phosphonates (HOP) and α-oxoesters (OE) have been described for the first time. The existence of a 2-oxo group in α-oxoaldehydes (OA) was a key factor in promoting the reaction of the tervalent phosphite form towards activated aldehydes (OA) in the synthesis of HOP.

Intermolecular Cyclopropanation of Iodonium Ylides and Electron-Deficient Alkenes through a Highly Efficient Catalyst-Free Process

2018 ◽  
Vol 7 (10) ◽  
pp. 2065-2068 ◽  
Author(s):  
Xiang Zhang ◽  
Rong Zeng ◽  
Xin Feng ◽  
Qing-Song Dai ◽  
Yue Liu ◽  
...  
Keyword(s):  
Efficient Catalyst ◽  
Catalyst Free ◽  
Highly Efficient ◽  
Free Process ◽  
Iodonium Ylides

Copper ferrite–graphene hybrid: a highly efficient magnetic catalyst for chemoselective reduction of nitroarenes

RSC Advances ◽  
2014 ◽  
Vol 4 (59) ◽  
pp. 31328-31332 ◽  
Author(s):  
Haiyan Zhang ◽  
Shutao Gao ◽  
Ningzhao Shang ◽  
Chun Wang ◽  
Zhi Wang
Keyword(s):  
Copper Ferrite ◽  
Hybrid Nanocomposite ◽  
Efficient Catalyst ◽  
Magnetic Catalyst ◽  
Highly Efficient ◽  
First Time

In this paper, an inexpensive and magnetically recyclable copper ferrite–graphene hybrid nanocomposite was synthesized and used as an efficient catalyst for the reduction of nitroarenes for the first time.

Highly Efficient, Catalyst-Free, Diastereoselective, Diversity-Oriented Synthesis of Dihydrocoumarin–Pyrrolidine–Spirooxindoles Bearing Three Contiguous Stereocenters

Synthesis ◽  
2019 ◽  
Vol 51 (11) ◽  
pp. 2339-2350 ◽  
Author(s):  
Xiong Zuo ◽  
Shuang Chen ◽  
Sheng-Wen Xu ◽  
Shun-Qin Chang ◽  
Xiong-Li Liu ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Bioactive Molecules ◽  
Acid Activation ◽  
Efficient Catalyst ◽  
Diversity Oriented Synthesis ◽  
Efficient Approach ◽  
Catalyst Free ◽  
Highly Efficient

A new methodology has been developed for the highly efficient diastereoselective construction of dihydrocoumarin–pyrrolidine–spirooxindole collections via a domino Michael/annulation reaction of 3-isothiocyanato oxindoles and coumarins under catalyst-free conditions. The resulting biologically important molecules bearing three pharmacophores and three contiguous stereocenters were obtained in up to 92% yield and >20:1 dr. It is noteworthy that utilization of a carboxylic acid activation/decarboxylation strategy represents an efficient approach for the domino Michael/annulation reaction of the chemically inert coumarin moiety. This protocol could expand candidate libraries, that will benefit the requirement for new bioactive molecules.

High-sensitivity stimuli-responsive polysiloxane synthesized via catalyst-free aza-Michael addition for ibuprofen loading and controlled release

RSC Advances ◽  
2016 ◽  
Vol 6 (101) ◽  
pp. 99414-99421 ◽  
Author(s):  
Shusheng Li ◽  
Shengyu Feng
Keyword(s):  
Controlled Release ◽  
Michael Addition ◽  
High Sensitivity ◽  
Stimuli Responsive ◽  
Efficient Catalyst ◽  
Catalyst Free ◽  
Highly Efficient

High-sensitive stimuli-responsive polysiloxanes with high sensitive respond to three changes of thermo-, pH-, and salinity were synthesized via a facile, highly efficient, catalyst-free aza-Michael addition of poly(aminopropylmethylsiloxane) with N-isopropylacrylamide.

A Highly Efficient and Stereocontrolled Synthesis of 2-Deoxy-1,5-thioanhydro-L-hexitols fromD-Glycals in a Tandem Nucleophilic Displacement Reaction

2006 ◽  
Vol 2006 (14) ◽  
pp. 3097-3104 ◽  
Author(s):  
Pietro Passacantilli ◽  
Clara Centore ◽  
Elena Ciliberti ◽  
Francesca Leonelli ◽  
Giovanni Piancatelli
Keyword(s):  
Displacement Reaction ◽  
Highly Efficient ◽  
Nucleophilic Displacement ◽  
Stereocontrolled Synthesis
Sign in / Sign up

Export Citation Format

Share Document