Self-immolative base-mediated conjugate release from triazolylmethylcarbamates

2015 ◽  
Vol 13 (32) ◽  
pp. 8703-8707 ◽  
Author(s):  
Christopher A. Blencowe ◽  
David W. Thornthwaite ◽  
Wayne Hayes ◽  
Andrew T. Russell
Keyword(s):  
Aromatic Amine ◽  
Reporter Group

A range of carbamate functionalized 1,4-disubstituted triazoles featuring a model aromatic amine reporter group (R) have been prepared via copper(i) catalysed azide–alkyne cycloaddition and revealed self-immolative characteristics under basic conditions.

Excess enthalpies of some aromatic amine + benzene mixtures

1979 ◽  
Vol 76 ◽  
pp. 381-382 ◽  
Author(s):  
Inmaculada Velasco ◽  
Santos Otín ◽  
Celso Gutiérrez-Losa
Keyword(s):  
Aromatic Amine ◽  
Excess Enthalpies

scholarly journals P.2.20 Epidemic of bladder cancer in japanese male workers exposed mainly to ortho-toluidine

2019 ◽  
Vol 76 (Suppl 1) ◽  
pp. A93.1-A93
Author(s):  
Makiko Nakano ◽  
Kazuyuki Omae ◽  
Yoko Eitaki ◽  
Satoko Iwasawa ◽  
Kota Fukai ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Aromatic Amine ◽  
Aromatic Amines ◽  
Organic Dyes ◽  
Cross Sectional Study ◽  
International Agency ◽  
Gross Hematuria ◽  
Cross Sectional ◽  
Exposed Workers ◽  
Medical Histories

BackgroundIn 2012, ortho-toluidine (OT) was listed as a Group 1 carcinogen by the International Agency for Research on Cancer, based on epidemiologic observations in workers co-exposed to OT and aromatic amines. Between 2014 and 2017, 10 cases of bladder cancer (BC) were identified in Japanese males working at two plants of the same company manufacturing intermediates of organic dyes and pigments.ObjectiveTo describe the features of the BC epidemic at the plants.MethodsWe conducted a cross-sectional study of 76 OT and/or aromatic amine-exposed workers including the 10 BC cases at the plants in 2017. The co-exposed aromatic amines were para-toluidine, ortho-anisidine, aniline, 2,4-dimethylaniline, and/or ortho-chloroaniline. Details of each worker’s job-site histories were obtained from the company records. Past medical symptoms and histories were checked in physician interviews. The subjects were divided into the BC group (n=10) and the non-BC group (n=66) and compared. No quantitative exposure data were available. The surrogate level of exposure to each aromatic amine was calculated as the summed job-weight-month in each process in each job-year.ResultsThe mean ages of the non-BC and BC groups were 50 and 56 years and the durations of employment were 23 and 20 years, respectively. The smoking rate in both groups was 80%. Significantly higher rates of gross hematuria (70%) and cystitis (70%) were identified in the BC group’s past medical histories. In the BC group, the surrogate levels of exposure to OT were higher than those of exposures to other aromatic amines. The surrogate levels were high in the job processes of filtering, rinsing, drying and packing products.ConclusionsThe subjects with BC were associated with a high surrogate level of exposure to OT. OT-exposed workers with past histories of gross hematuria and cystitis need a careful follow-up.

ChemInform Abstract: COMPLEXES OF GALLIUM TRIBROMIDE WITH SOME AROMATIC AMINE OXIDES

1978 ◽  
Vol 9 (22) ◽  
Author(s):  
A. SANCHEZ ◽  
J. S. CASAS ◽  
J. SORDO ◽  
J. R. MASAGUER
Keyword(s):  
Aromatic Amine ◽  
Amine Oxides

scholarly journals Cubane Cu4I4(phosphine)4 Complexes as New Co-initiator for Free Radical Photopolymerization: Towards Aromatic Amine-Free Systems

2021 ◽  
Author(s):  
Jacques Lalevée ◽  
Fatima Hammoud ◽  
Mahmoud Rahal ◽  
Julien Egly ◽  
Fabrice Morlet-Savary ◽  
...  
Keyword(s):  
Free Radical ◽  
Radical Polymerization ◽  
Aromatic Amine ◽  
Free Radical Polymerization ◽  
Copper Iodide ◽  
Free Radical Photopolymerization ◽  
Acrylate Monomers ◽  
First Time

The investigation of copper-iodide cubane derivatives as new co-initiators for the free radical polymerization (FRP) of acrylate monomers under mild irradiation conditions is described for the first time here. These...

Stimulation of Bacillus sp. by lipopeptide biosurfactant for the degradation of aromatic amine 4-Chloroaniline

2021 ◽  
Vol 415 ◽  
pp. 125716
Author(s):  
C. Femina Carolin ◽  
P. Senthil Kumar ◽  
B. Chitra ◽  
C. Fetcia Jackulin ◽  
Racchana Ramamurthy
Keyword(s):  
Aromatic Amine ◽  
Bacillus Sp ◽  
Lipopeptide Biosurfactant ◽  
Stimulation Of

scholarly journals Synthesis, Characterization and Study of the Biological activity of Some Aldimines Derivatives

2006 ◽  
Vol 3 (4) ◽  
pp. 257-261 ◽  
Author(s):  
Mohamed N. Ibrahim ◽  
Hazem K. Al - Deeb
Keyword(s):  
Biological Activity ◽  
Schiff Bases ◽  
Aromatic Aldehyde ◽  
Aromatic Amine ◽  
Elemental Analysis ◽  
Primary Aromatic Amine ◽  
H Nmr

A number of imines derivatives have been synthesized, they were obtained by condensation of aromatic aldehyde derivatives with primary aromatic amine derivatives. Their structures have been characterised by IR,1H NMR in addition to the elemental analysis. The biological activity of these imines (which are also known as Schiff bases) were examined against different type of microorganisms and they found to have considerable activity in comparison with the most commonly used antibiotics.

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