Highly enantioselective asymmetric transfer hydrogenation (ATH) of α-phthalimide ketones

2015 ◽  
Vol 13 (27) ◽  
pp. 7513-7516 ◽  
Author(s):  
Zhou Xu ◽  
Yong Li ◽  
Jing Liu ◽  
Nan Wu ◽  
Ke Li ◽  
...  
Keyword(s):  
Good Yield ◽  
Amino Alcohols ◽  
Optically Active ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation

Optically active amino alcohols are obtained in good yield and excellent ee via an efficient asymmetric transfer hydrogenation (ATH) of α-phthalimide ketones.

ChemInform Abstract: Synthesis of Optically Active β-Amino Alcohols by Asymmetric Transfer Hydrogenation of α-Amino Ketones.

ChemInform ◽  
2010 ◽  
Vol 41 (28) ◽  
pp. no-no
Author(s):  
Zhou Xu ◽  
Songlei Zhu ◽  
Yongmin Liu ◽  
Ling He ◽  
Zhicong Geng ◽  
...  
Keyword(s):  
Amino Alcohols ◽  
Optically Active ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation

scholarly journals Preparation of Mesoporous Silica-Supported Chiral Amino Alcohols for the Enantioselective Addition of Diethylzinc to Aldehyde and Asymmetric Transfer Hydrogenation to Ketones

2015 ◽  
Vol 2015 ◽  
pp. 1-6
Author(s):  
Shaheen M. Sarkar ◽  
Md. Eaqub Ali ◽  
Md. Lutfor Rahman ◽  
Mashitah Mohd Yusoff
Keyword(s):  
Mesoporous Silica ◽  
Amino Alcohols ◽  
Optically Active ◽  
Transfer Hydrogenation ◽  
Catalytic Process ◽  
Asymmetric Transfer Hydrogenation ◽  
Chiral Catalyst ◽  
Aromatic Alcohols ◽  
Enantioselective Addition ◽  
Cubic Mesoporous

Optically active (−)-ephedrine, (−)-norephedrine, and (−)-prolinol were immobilized onto cubic mesoporous MCM-48 silica. The immobilized amino alcohols served as a heterogeneous chiral catalyst for the asymmetric addition of diethylzinc to aldehydes and transfer hydrogenation to ketones. The developed catalytic process yielded optically enriches secondary aromatic alcohols with 92–99% conversion and 70–82% enantioselectivity.

Synthesis of Optically Active β-Amino Alcohols by Asymmetric Transfer Hydrogenation of α-Amino Ketones

Synthesis ◽  
2009 ◽  
Vol 2010 (05) ◽  
pp. 811-817 ◽  
Author(s):  
Zhou Xu ◽  
Yawen Zhang ◽  
Songlei Zhu ◽  
Yongmin Liu ◽  
Ling He ◽  
...  
Keyword(s):  
Amino Alcohols ◽  
Optically Active ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation
Sign in / Sign up

Export Citation Format

Share Document