Zwitterionic supramolecular nanoparticles: self-assembly and responsive properties

Nanoscale ◽  
2015 ◽  
Vol 7 (17) ◽  
pp. 7915-7919 ◽  
Author(s):  
Carmen Stoffelen ◽  
Jurriaan Huskens
Keyword(s):  
Self Assembly ◽  
Ph Responsive ◽  
Supramolecular Nanoparticles

Zwitterionic supramolecular nanoparticles (ZSNPs) show photo- and pH-responsive properties and are stable in high-BSA solutions.

Biocompatible, chimeric peptide-condensed supramolecular nanoparticles for tumor cell-specific siRNA delivery and gene silencing

2014 ◽  
Vol 50 (58) ◽  
pp. 7806-7809 ◽  
Author(s):  
Hangxiang Wang ◽  
Wei Chen ◽  
Haiyang Xie ◽  
Xuyong Wei ◽  
Shengyong Yin ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Gene Silencing ◽  
Delivery System ◽  
Self Assembly ◽  
Sirna Delivery ◽  
Single Step ◽  
Chimeric Peptide ◽  
Supramolecular Nanoparticles ◽  
Sirna Delivery System

A practical and tumor cell-specific siRNA delivery system was developedviasingle-step self-assembly of an arginine-rich chimeric peptide with siRNA.

Construction of a pH-sensitive self-assembly in aqueous solutions based on a dansyl-modified β-cyclodextrin

Soft Matter ◽  
2021 ◽  
Author(s):  
Bing Jiang ◽  
Yu Liu ◽  
Linlin Zhao ◽  
Li Zhao ◽  
Ce Wang ◽  
...  
Keyword(s):  
Aqueous Solutions ◽  
Self Assembly ◽  
Ph Sensitive ◽  
Ph Responsive ◽  
Ph Range

Here we present a pH-responsive self-assembly based on a β-cyclodextrin (β-CD) derivative bearing a dansyl terminus (βCD-C6-Dns). Vesicular structures were formed over the entire studied pH range (8.5-0.7); however, the...

Facile synthesis and self-assembly behaviour of pH-responsive degradable polyacetal dendrimers

2016 ◽  
Vol 7 (40) ◽  
pp. 6154-6158 ◽  
Author(s):  
Da Huang ◽  
Fei Yang ◽  
Xing Wang ◽  
Hong Shen ◽  
Yezi You ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Self Assembly ◽  
Ph Responsive ◽  
Facile Synthesis

Well-defined POSS hybrid polyacetal dendrimers functionalized with terminal polyethylene glycol and zwitterion could assemble into pH-responsive degradable micelles and nanofibers.

Self-Assembly Thermodynamics of pH-Responsive Amino-Acid-Based Polymers with a Nonionic Surfactant

Langmuir ◽  
2014 ◽  
Vol 30 (38) ◽  
pp. 11307-11318 ◽  
Author(s):  
Anna Bogomolova ◽  
Sandro Keller ◽  
Johannes Klingler ◽  
Marian Sedlak ◽  
Dmytro Rak ◽  
...  
Keyword(s):  
Amino Acid ◽  
Nonionic Surfactant ◽  
Self Assembly ◽  
Ph Responsive

A water-soluble biphen[3]arene: synthesis, host–guest complexation, and application in controllable self-assembly and controlled release

2015 ◽  
Vol 51 (20) ◽  
pp. 4188-4191 ◽  
Author(s):  
Jiong Zhou ◽  
Guocan Yu ◽  
Li Shao ◽  
Bin Hua ◽  
Feihe Huang
Keyword(s):  
Controlled Release ◽  
Self Assembly ◽  
Water Soluble ◽  
Ammonium Salts ◽  
Ph Responsive ◽  
Recognition Motif

The first water-soluble biphen[3]arene was synthesized. Its pH-responsive host–guest complexation with secondary ammonium salts in water was investigated. This novel recognition motif was further used in controllable self-assembly and controlled release.

scholarly journals pH-Responsive Schizophrenic Diblock Copolymers Prepared by Polymerization-Induced Self-Assembly

2017 ◽  
Vol 50 (16) ◽  
pp. 6108-6116 ◽  
Author(s):  
Sarah L. Canning ◽  
Thomas J. Neal ◽  
Steven P. Armes
Keyword(s):  
Self Assembly ◽  
Diblock Copolymers ◽  
Ph Responsive

scholarly journals Carbon Nano-Onions Reinforced Multilayered Thin Film System for Stimuli-Responsive Drug Release

Pharmaceutics ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 1208
Author(s):  
Narsimha Mamidi ◽  
Ramiro Velasco Delgadillo ◽  
Aldo Gonzáles Ortiz ◽  
Enrique Barrera
Keyword(s):  
Thin Film ◽  
Thin Films ◽  
Drug Release ◽  
Self Assembly ◽  
Critical Role ◽  
Layer By Layer ◽  
Film System ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Thin Film System

Herein, poly (N-(4-aminophenyl) methacrylamide))-carbon nano-onions (PAPMA-CNOs = f-CNOs) and anilinated-poly (ether ether ketone) (AN-PEEK) have synthesized, and AN-PEEK/f-CNOs composite thin films were primed via layer-by-layer (LbL) self-assembly for stimuli-responsive drug release. The obtained thin films exhibited pH-responsive drug release in a controlled manner; pH 4.5 = 99.2% and pH 6.5 = 59.3% of doxorubicin (DOX) release was observed over 15 days. Supramolecular π-π stacking interactions between f-CNOs and DOX played a critical role in controlling drug release from thin films. Cell viability was studied with human osteoblast cells and augmented viability was perceived. Moreover, the thin films presented 891.4 ± 8.2 MPa of the tensile strength (σult), 43.2 ± 1.1 GPa of Young’s modulus (E), and 164.5 ± 1.7 Jg−1 of toughness (K). Quantitative scrutiny revealed that the well-ordered aligned nanofibers provide critical interphase, and this could be responsible for augmented tensile properties. Nonetheless, a pH-responsive and mechanically robust biocompatible thin-film system may show potential applications in the biomedical field.

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