A novel topological centrality measure capturing biologically important proteins

2016 ◽  
Vol 12 (2) ◽  
pp. 666-673 ◽  
Author(s):  
Muhammed Erkan Karabekmez ◽  
Betul Kirdar
Keyword(s):  
Protein Interaction ◽  
Protein Interaction Network ◽  
Interaction Network ◽  
Weighted Sum ◽  
Eigenvector Centrality ◽  
Graph Spectra ◽  
Protein Protein Interaction ◽  
Topological Centrality ◽  
Important Nodes ◽  
Protein Protein Interaction Network

In the present study, a novel metric of centrality—weighted sum of loads eigenvector centrality (WSL-EC)—based on graph spectra is defined and its performance in identifying topologically and biologically important nodes is comparatively investigated with common metrics of centrality in a human protein–protein interaction network.

scholarly journals Diabetic Retinopathy and Laser Therapy in Rats: A Protein-Protein Interaction Network Analysis

2017 ◽  
Vol 8 (Suppl 1) ◽  
pp. S20-S21 ◽  
Author(s):  
Akram Safaei ◽  
Mostafa Rezaei Tavirani ◽  
Mona Zamanian Azodi ◽  
Alireza Lashay ◽  
Seyed Farzad Mohammadi ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Network Analysis ◽  
Laser Therapy ◽  
Protein Interaction ◽  
Protein Interaction Network ◽  
Interaction Network ◽  
Protein Protein Interaction ◽  
Protein Protein Interaction Network
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