Genetic analysis of the clonal stability of Chinese hamster ovary cells for recombinant protein production

2016 ◽  
Vol 12 (1) ◽  
pp. 102-109 ◽  
Author(s):  
Hongwen Li ◽  
Kaiming Chen ◽  
Zhe Wang ◽  
Dong Li ◽  
Jiannan Lin ◽  
...  

Up-regulation of cell proliferation-related genes is potentially a major cause of production instability of the CHO cell line.

2014 ◽  
Vol 9 (9) ◽  
pp. 1140-1151 ◽  
Author(s):  
Wan Ping Loh ◽  
Bernard Loo ◽  
Lihan Zhou ◽  
Peiqing Zhang ◽  
Dong-Yup Lee ◽  
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