In silico research to assist the investigation of carboxamide derivatives as potent TRPV1 antagonists

2015 ◽  
Vol 11 (11) ◽  
pp. 2885-2899 ◽  
Author(s):  
Jinghui Wang ◽  
Yan Li ◽  
Yinfeng Yang ◽  
Jian Du ◽  
Shuwei Zhang ◽  
...  
Keyword(s):  
Diabetic Neuropathy ◽  
Cancer Pain ◽  
In Silico ◽  
Essential Role ◽  
Transient Receptor Potential ◽  
Receptor Potential ◽  
Cation Channel ◽  
Transient Receptor Potential Vanilloid ◽  
Transient Receptor

The transient receptor potential vanilloid type 1 (TRPV1), a non-selective cation channel, is known for its essential role in the pathogenesis of various pain conditions such as nerve damage induced hyperalgesia, diabetic neuropathy and cancer pain.

scholarly journals Activation of Transient Receptor Potential Vanilloid Type-1 Channel Prevents Adipogenesis and Obesity

2007 ◽  
Vol 100 (7) ◽  
pp. 1063-1070 ◽  
Author(s):  
Li Li Zhang ◽  
Dao Yan Liu ◽  
Li Qun Ma ◽  
Zhi Dan Luo ◽  
Ting Bing Cao ◽  
...  
Keyword(s):  
Transient Receptor Potential ◽  
Receptor Potential ◽  
Transient Receptor Potential Vanilloid ◽  
Transient Receptor
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