Deoxygenation of carbonyl compounds using an alcohol as an efficient reducing agent catalyzed by oxo-rhenium complexes

2016 ◽  
Vol 18 (9) ◽  
pp. 2675-2681 ◽  
Author(s):  
Joana R. Bernardo ◽  
Ana C. Fernandes
Keyword(s):  
Catalytic System ◽  
Carbonyl Compounds ◽  
Reducing Agent ◽  
Rhenium Complexes

The catalytic system 3-pentanol/ReOCl3(SMe2)(OPPh3) was very efficient for the deoxygenation of carbonyl compounds.

Sodium borohydride: A versatile reagent in the reductive N-monoalkylation of α-amino acids and α-amino methyl esters

2002 ◽  
Vol 80 (7) ◽  
pp. 779-788 ◽  
Author(s):  
Giancarlo Verardo ◽  
Paola Geatti ◽  
Elena Pol ◽  
Angelo G Giumanini
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Sodium Borohydride ◽  
Carbonyl Compounds ◽  
Condensation Reaction ◽  
Methyl Esters ◽  
Reducing Agent ◽  
Reductive Condensation ◽  
Versatile Reagent

α-Amino acids and α-amino methyl esters are easily converted to their N-monoalkyl derivatives by a reductive condensation reaction using several carbonyl compounds in the presence of sodium borohydride. This reducing agent has shown a wide versatility with minor but essential procedural variations. The reaction allows the α-monodeuterium labeling of the new N-substituent by use of sodium borodeuteride.Key words: α-amino acid, α-amino methyl esters, sodium borohydride, reductive N-monoalkylation, carbonyl compounds.

Au@zirconium-phosphonate nanoparticles as an effective catalytic system for the chemoselective and switchable reduction of nitroarenes

2019 ◽  
Vol 21 (3) ◽  
pp. 614-626 ◽  
Author(s):  
Francesco Ferlin ◽  
Matteo Cappelletti ◽  
Riccardo Vivani ◽  
Monica Pica ◽  
Oriana Piermatti ◽  
...  
Keyword(s):  
Catalytic System ◽  
Zirconium Phosphate ◽  
High Efficiency ◽  
Reducing Agent ◽  
Layer Surface ◽  
Flow Conditions ◽  
Zirconium Phosphonate

Zirconium phosphate bearing aminoethyl groups on the layer surface, ZP(AEP), was used to immobilize AuNPs. The gold-based catalyst proved its high efficiency for the chemoselective reduction of nitroarenes under both batch and flow conditions by using NaBH4 as a reducing agent.

2-Phenylbenzothiazoline as a Reducing Agent in the Conjugate Reduction of α,β-Unsaturated Carbonyl Compounds

Synthesis ◽  
1984 ◽  
Vol 1984 (04) ◽  
pp. 308-310 ◽  
Author(s):  
Hidenori Chikashita ◽  
Makoto Miyazaki ◽  
Kazuyoshi Itoh
Keyword(s):  
Carbonyl Compounds ◽  
Reducing Agent ◽  
Conjugate Reduction

scholarly journals An easily recoverable and recyclable homogeneous polyester-based Pd catalytic system for the hydrogenation of α,β-unsaturated carbonyl compounds

2015 ◽  
Vol 69 ◽  
pp. 228-233 ◽  
Author(s):  
Mattia Bartoli ◽  
Luca Rosi ◽  
Giorgio Petrucci ◽  
Lidia Armelao ◽  
Werner Oberhauser ◽  
...  
Keyword(s):  
Catalytic System ◽  
Carbonyl Compounds

Cu(I)-Bis(phosphine) Dioxides as catalysts for the Enantioselective α-Arylation of Carbonyl Compounds

Synlett ◽  
2021 ◽  
Author(s):  
Margarita Escudero-Casao ◽  
Giulia Licini ◽  
Manuel Orlandi
Keyword(s):  
Reaction Mechanism ◽  
Transition Metal ◽  
Catalytic System ◽  
Carbonyl Compounds ◽  
Research Area ◽  
Metal Catalysts ◽  
Transition Metal Catalysts ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed

The transition metal catalyzed α-arylation of carbonyl compounds was first reported by Buchwald and Hartwig in 1997. This transformation has been used and studied extensively over the last two decades. Enantioselective variants were also developed that allow for controlling the product stereochemistry. However, these suffer several limitations in the context of formation of tertiary stereocenters. Presented here is our group’s contribution to this research area. The chiral Cu-bis(phosphine) dioxides catalytic system that we reported allowed accessing the enantioselective α-arylation of ketones that were not suitable for this transformation before in good yields and er up to 97.5:2.5. Preliminary insight and speculation concerning the reaction mechanism involving the unusual pairing of bis(phosphine) dioxides with transition metal catalysts is also given.

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