scholarly journals Highly luminescent gold nanoparticles: effect of ruthenium distance for nanoprobes with enhanced lifetimes

2015 ◽  
Vol 185 ◽  
pp. 219-231 ◽  
Author(s):  
Shani A. M. Osborne ◽  
Zoe Pikramenou
Keyword(s):  
Gold Nanoparticles ◽  
Metal Complexes ◽  
Photophysical Properties ◽  
Gold Surface ◽  
Luminescence Lifetime ◽  
Thiol Groups ◽  
Fluorinated Surfactant ◽  
Surface Luminescence ◽  
Surface Active ◽  
Luminescent Centre

The photophysical properties of gold nanoparticles, AuNPs, with sizes of 13, 50 and 100 nm in diameter, coated with surface-active ruthenium complexes have been studied to investigate the effect of the distance of the ruthenium luminescent centre from the gold surface. Luminescence lifetimes of the three ruthenium probes, RuS1, RuS6 and RuS12, with different length spacer units between the surface active groups and the ruthenium centre were taken. The metal complexes were attached to AuNP13, AuNP50 and AuNP100via thiol groups using a method of precoating the nanoparticles with a fluorinated surfactant. The luminescence lifetime of the longer spacer unit complex, RuS12, was enhanced by 70% upon attachment to the AuNP when compared to the increase of the short and medium linker unit complexes, RuS1 (20%) and RuS6 (40%) respectively. The effect of the surfactant in the lifetime increase of the ruthenium coated AuNPs was shown to be larger for the medium spacer probe, RuS6. There was no effect of the change of the size of the AuNPs from 13 to 50 or 100 nm.

scholarly journals Surface Adsorption of the Alpha-Emitter Astatine-211 to Gold Nanoparticles Is Stable In Vivo and Potentially Useful in Radionuclide Therapy

2021 ◽  
Vol 2 (4) ◽  
pp. 196-207
Author(s):  
Emanuel Sporer ◽  
Christian B. M. Poulie ◽  
Sture Lindegren ◽  
Emma Aneheim ◽  
Holger Jensen ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Surface Adsorption ◽  
Radiochemical Yield ◽  
Gold Surface ◽  
Mouse Serum ◽  
Control Group ◽  
Alpha Emitter ◽  
Before And After ◽  
The Stability

Targeted α-therapy (TAT) can eradicate tumor metastases while limiting overall toxicity. One of the most promising α-particle emitters is astatine-211 (211At). However, 211At-carbon bonds are notoriously unstable in vivo and no chelators are available. This hampers its adoption in TAT. In this study, the stability of 211At on the surface of gold nanoparticles (AuNPs) was investigated. The employed AuNPs had sizes in the 25–50 nm range. Radiolabeling by non-specific surface-adsorption in >99% radiochemical yield was achieved by mixing 211At and AuNPs both before and after polyethylene glycol (PEG) coating. The resulting 211At-AuNPs were first challenged by harsh oxidation with sodium hypochlorite, removing roughly 50% of the attached 211At. Second, incubation in mouse serum followed by a customized stability test, showed a stability of >95% after 4 h in serum. This high stability was further confirmed in an in vivo study, with comparison to a control group of free 211At. The AuNP-associated 211At showed low uptake in stomach and thyroid, which are hallmark organs of uptake of free 211At, combined with long circulation and high liver and spleen uptake, consistent with nanoparticle biodistribution. These results support that gold surface-adsorbed 211At has high biological stability and is a potentially useful delivery system in TAT.

The Photophysical Properties of Hybrid Metal Complexes Containing both 2,2′-Bipyridine and 2,2′:6′,2′′-Terpyridine Units

2003 ◽  
Vol 2003 (5) ◽  
pp. 955-959 ◽  
Author(s):  
Anthony Harriman ◽  
Muriel Hissler ◽  
Abderrahim Khatyr ◽  
Raymond Ziessel
Keyword(s):  
Metal Complexes ◽  
Photophysical Properties

Synthesis and photophysical properties of metal complexes of curcumin dyes: Solvatochromism, acidochromism, and photoactivity

2022 ◽  
Vol 198 ◽  
pp. 110011
Author(s):  
Bruna M. de França ◽  
Simone S.C. Oliveira ◽  
Lucieri O.P. Souza ◽  
Thaís P. Mello ◽  
André L.S. Santos ◽  
...  
Keyword(s):  
Metal Complexes ◽  
Photophysical Properties

Ligand photodissociation in Ru(ii)–1,4,7-triazacyclononane complexes enhances water oxidation and enables electrochemical generation of surface active species

2020 ◽  
Vol 10 (10) ◽  
pp. 3399-3408 ◽  
Author(s):  
Hussein A. Younus ◽  
Nazir Ahmad ◽  
Ibrahim Yildiz ◽  
Serge Zhuiykov ◽  
Shiguo Zhang ◽  
...  
Keyword(s):  
Metal Complexes ◽  
Partial Oxidation ◽  
Water Oxidation ◽  
Active Species ◽  
Electrochemical Generation ◽  
Surface Active ◽  
Complete Dissociation

Ligand transformations involved in metal complexes during water oxidation (WO), such as ligand decomposition, partial oxidation, or complete dissociation have been reported, however, ligand photodissociation has not been reported yet.

scholarly journals Functionalization of Gold Nanoparticles by Inorganic Entities

Nanomaterials ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 548 ◽  
Author(s):  
Frédéric Dumur ◽  
Eddy Dumas ◽  
Cédric R. Mayer
Keyword(s):  
Gold Nanoparticles ◽  
Rapid Development ◽  
Gold Surface ◽  
Intrinsic Properties ◽  
Au Nps ◽  
Gold Core ◽  
Inorganic Systems ◽  
Wide Range ◽  
Different Types ◽  
Electron Donating Groups

The great affinity of gold surface for numerous electron-donating groups has largely contributed to the rapid development of functionalized gold nanoparticles (Au-NPs). In the last years, a new subclass of nanocomposite has emerged, based on the association of inorganic molecular entities (IME) with Au-NPs. This highly extended and diversified subclass was promoted by the synergy between the intrinsic properties of the shell and the gold core. This review—divided into four main parts—focuses on an introductory section of the basic notions related to the stabilization of gold nanoparticles and defines in a second part the key role played by the functionalizing agent. Then, we present a wide range of inorganic molecular entities used to prepare these nanocomposites (NCs). In particular, we focus on four different types of inorganic systems, their topologies, and their current applications. Finally, the most recent applications are described before an overview of this new emerging field of research.

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