Catalytic functionalization of low reactive C(sp3)–H and C(sp2)–H bonds of alkanes and arenes by carbene transfer from diazo compounds

2015 ◽  
Vol 44 (47) ◽  
pp. 20295-20307 ◽  
Author(s):  
Ana Caballero ◽  
M. Mar Díaz-Requejo ◽  
Manuel R. Fructos ◽  
Andrea Olmos ◽  
Juan Urbano ◽  
...  
Keyword(s):  
Diazo Compounds ◽  
Carbene Transfer ◽  
Catalytic Functionalization

Catalytic Functionalization of Indoles by Copper-Mediated Carbene Transfer

ChemCatChem ◽  
2014 ◽  
Vol 6 (7) ◽  
pp. 2047-2052 ◽  
Author(s):  
Manuela Delgado-Rebollo ◽  
Auxiliadora Prieto ◽  
Pedro J. Pérez
Keyword(s):  
Carbene Transfer ◽  
Catalytic Functionalization

ChemInform Abstract: Catalytic Functionalization of Indoles by Copper-Mediated Carbene Transfer.

ChemInform ◽  
2014 ◽  
Vol 46 (3) ◽  
pp. no-no
Author(s):  
Manuela Delgado-Rebollo ◽  
Auxiliadora Prieto ◽  
Pedro J. Perez
Keyword(s):  
Carbene Transfer ◽  
Catalytic Functionalization

scholarly journals Bis(imino)pyridine iron complexes for catalytic carbene transfer reactions

2019 ◽  
Vol 10 (34) ◽  
pp. 7958-7963 ◽  
Author(s):  
Ban Wang ◽  
Isaac G. Howard ◽  
Jackson W. Pope ◽  
Eric D. Conte ◽  
Yongming Deng
Keyword(s):  
Iron Complexes ◽  
Iron Complex ◽  
Diazo Compounds ◽  
Transfer Reactions ◽  
Donor Acceptor ◽  
Carbene Transfer ◽  
First Time

The bis(imino)pyridine iron complex, for the first time, is developed as an effective metal carbene catalyst for carbene transfer reactions of donor–acceptor diazo compounds.

General Cyclopropane Assembly via Enantioselective Redox-Active Carbene Transfer to Aliphatic Olefins

2018 ◽  
Author(s):  
Marc Montesinos-Magraner ◽  
Matteo Costantini ◽  
Rodrigo Ramirez-Contreras ◽  
Michael E. Muratore ◽  
Magnus J. Johansson ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Asymmetric Synthesis ◽  
Chemical Space ◽  
Synthetic Approach ◽  
Asymmetric Cyclopropanation ◽  
Redox Active ◽  
Wide Range ◽  
Leaving Group ◽  
Stereoelectronic Properties ◽  
Carbene Transfer

Asymmetric cyclopropane synthesis currently requires bespoke strategies, methods, substrates and reagents, even when targeting similar compounds. This limits the speed and chemical space available for discovery campaigns. Here we introduce a practical and versatile diazocompound, and we demonstrate its performance in the first unified asymmetric synthesis of functionalized cyclopropanes. We found that the redox-active leaving group in this reagent enhances the reactivity and selectivity of geminal carbene transfer. This effect enabled the asymmetric cyclopropanation of a wide range of olefins including unactivated aliphatic alkenes, enabling the 3-step total synthesis of (–)-dictyopterene A. This unified synthetic approach delivers high enantioselectivities that are independent of the stereoelectronic properties of the functional groups transferred. Our results demonstrate that orthogonally-differentiated diazocompounds are viable and advantageous equivalents of single-carbon chirons<i>.</i>

New catalysts for the reduction of aromatic diazo compounds by alcohols to hydrocarbons

1983 ◽  
Vol 32 (4) ◽  
pp. 858-861 ◽  
Author(s):  
V. S. Lenenko ◽  
A. P. Borisov ◽  
V. D. Makhaev ◽  
E. I. Mysov ◽  
V. B. Shur ◽  
...  
Keyword(s):  
Diazo Compounds
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