Copper(ii) mediated phenol ring nitration by nitrogen dioxide

2015 ◽  
Vol 44 (46) ◽  
pp. 19909-19917 ◽  
Author(s):  
Vikash Kumar ◽  
Somnath Ghosh ◽  
Anoop Kumar Saini ◽  
Shaikh M. Mobin ◽  
Biplab Mondal
Keyword(s):  
Complex Formation ◽  
Nitrogen Dioxide ◽  
Phenoxyl Radical ◽  
Spectroscopic Evidence ◽  
Radical Complex ◽  
Reaction Proceeds ◽  
P Addition ◽  
Phenol Ring

Addition of nitrogen dioxide in the THF solutions of Cu(ii) complexes of N2O2type ligands, L1H2and L2H2resulted in the nitration at the 4-position of coordinated equatorial phenolate ring of the ligand frameworks. Spectroscopic evidence suggests that the reaction proceeds through a phenoxyl radical complex formation.

Phenol ring nitration induced by the unprecedented reduction of the Cu(ii) centre by nitrogen dioxide

2013 ◽  
Vol 42 (46) ◽  
pp. 16264 ◽  
Author(s):  
Vikash Kumar ◽  
Aswini Kalita ◽  
Biplab Mondal
Keyword(s):  
Nitrogen Dioxide ◽  
Phenol Ring

Double oxidation localizes spin in a Ni bis-phenoxyl radical complex

2013 ◽  
Vol 42 (11) ◽  
pp. 3950 ◽  
Author(s):  
Tim J. Dunn ◽  
Michael I. Webb ◽  
Khatera Hazin ◽  
Pratik Verma ◽  
Erik C. Wasinger ◽  
...  
Keyword(s):  
Phenoxyl Radical ◽  
Radical Complex ◽  
Double Oxidation

Reversible radical complex formation of an organometallic diplatinum(IV) compound

2007 ◽  
Vol 692 (15) ◽  
pp. 3151-3155 ◽  
Author(s):  
Cüneyt Kavakli ◽  
Anders Gabrielsson ◽  
Monika Sieger ◽  
Brigitte Schwederski ◽  
Mark Niemeyer ◽  
...  
Keyword(s):  
Complex Formation ◽  
Radical Complex

scholarly journals Ferrous sulphate does not directly affect pteroylmonoglutamic acid absorption in rats

1994 ◽  
Vol 72 (3) ◽  
pp. 447-453
Author(s):  
Norman R. C. Campbell ◽  
Brian B. Hasinoff ◽  
Mukhtiar Slngh ◽  
Susan Robertson
Keyword(s):  
Complex Formation ◽  
Ferrous Sulphate ◽  
Tris Buffer ◽  
Spectroscopic Evidence ◽  
Aqueous Dmso ◽  
Acid Absorption ◽  
Human Dose ◽  
Fe Ions

A variety of compounds which bind to Fe have substantial reductions in absorption when co-administered with Fe compounds. The binding of both Fe2+ and Fe3+ ions to pteroylmonoglutamic acid and the pteroylmonoglutamate dianion was examined in vitro. In dimethylsulphoxide (DMSO) alone, pteroylmonoglutamate formed a 2:1 (pteroylmonoglutamate: Fe3+ ion) complex. However, in DMSO–aqueous Bis-Tris buffer (4:1, v/v; pH 6.0) no evidence of complex formation could be seen. Likewise spectroscopic evidence was obtained for complex formation with Fe2+ ion and pteroylmonoglutamate in DMSO alone but not in the aqueous DMSO buffer. In vivo studies examined the effect of FeSO4 on pteroylmonoglutamic acid absorption in an isolated perfused rat jejunal model of nutrient absorption. The dose of pteroylmonoglutamic acid approximated a human dose of 1 mg for the rat, while the FeSO4 doses were chosen to represent 6.4 mg, 64 mg and 300 mg human doses. There was no significant effect of FeSO4 on pteroylmonoglutamic acid absorption or instability of pteroylmonoglutamic acid in vivo in the presence of FeSO4 in the rat. Although 2:1 binding of pteroylmonoglutamic acid to Fe ions could be demonstrated in DMSO alone, no binding could be demonstrated in DMSO–Bis-Tris buffer (4:1, v/v; pH 6.0). It is unlikely that there will be a significant reduction in pteroylmonoglutamic acid absorption during concurrent ingestion of Fe preparations.

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