Prospects for point-of-care pathogen diagnostics using surface-enhanced Raman scattering (SERS)

2016 ◽  
Vol 45 (14) ◽  
pp. 3865-3882 ◽  
Author(s):  
Jennifer H. Granger ◽  
Nicholas E. Schlotter ◽  
Alexis C. Crawford ◽  
Marc D. Porter
Keyword(s):  
Raman Scattering ◽  
Pathogen Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Scattering ◽  
Recent Advances ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

This review highlights recent advances in the application of surface-enhanced Raman scattering (SERS) in pathogen detection and discusses many of the challenges in moving this technology to the point-of-care (POC) arena.

Recent advances in surface-enhanced Raman scattering-based microdevices for point-of-care diagnosis of viruses and bacteria

Nanoscale ◽  
2020 ◽  
Vol 12 (42) ◽  
pp. 21560-21570
Author(s):  
Hao Chen ◽  
Anupam Das ◽  
Liyan Bi ◽  
Namhyun Choi ◽  
Joung-Il Moon ◽  
...  
Keyword(s):  
Infectious Diseases ◽  
Raman Scattering ◽  
Point Of Care ◽  
Surface Enhanced Raman Scattering ◽  
Recent Advances ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

This minireview reports the recent advances in surface-enhanced Raman scattering (SERS)-based assay devices for the diagnosis of infectious diseases.

scholarly journals Surface-Enhanced Raman Scattering-Based Lateral-Flow Immunoassay

Nanomaterials ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 2228
Author(s):  
Boris Khlebtsov ◽  
Nikolai Khlebtsov
Keyword(s):  
Raman Scattering ◽  
Point Of Care ◽  
Surface Enhanced Raman Scattering ◽  
Environmental Safety ◽  
Lateral Flow ◽  
Wide Range ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Low Sensitivity

Lateral flow immunoassays (LFIAs) have been developed and used in a wide range of applications, in point-of-care disease diagnoses, environmental safety, and food control. However, in its classical version, it has low sensitivity and can only perform semiquantitative detection, based on colorimetric signals. Over the past decade, surface-enhanced Raman scattering (SERS) tags have been developed in order to decrease the detection limit and enable the quantitative analysis of analytes. Of note, these tags needed new readout systems and signal processing algorithms, while the LFIA design remained unchanged. This review highlights SERS strategies of signal enhancement for LFIAs. The types of labels used, the possible gain in sensitivity from their use, methods of reading and processing the signal, and the prospects for use are discussed.

Visible-light and near-infrared fluorescence and surface-enhanced Raman scattering point-of-care sensing and bio-imaging: a review

2022 ◽  
Author(s):  
Yingjie Hang ◽  
Jennifer Boryczka ◽  
Nianqiang Wu
Keyword(s):  
Raman Scattering ◽  
Visible Light ◽  
Near Infrared ◽  
Point Of Care ◽  
Surface Enhanced Raman Scattering ◽  
Near Infrared Fluorescence ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Bio Imaging ◽  
Enhanced Raman Scattering

This article reviews the principles, design and applications of visible-light and near-infrared fluorescence and surface-enhanced Raman scattering in point-of-care testing and bio-imaging.

Graphene-based nanoplatforms for surface-enhanced Raman scattering sensing

The Analyst ◽  
2018 ◽  
Vol 143 (21) ◽  
pp. 5074-5089 ◽  
Author(s):  
Zhuqing Wang ◽  
Shasha Wu ◽  
Lucio Colombi Ciacchi ◽  
Gang Wei
Keyword(s):  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Sensing Applications ◽  
Recent Advances ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Sers Sensing

We demonstrate recent advances in the fabrication and SERS sensing applications of graphene-based nanoplatforms.

scholarly journals Recent Advances Towards Point-Of-Care Applications of Surface-Enhanced Raman Scattering Sensing

2021 ◽  
Vol 9 ◽  
Author(s):  
Steven Quarin ◽  
Pietro Strobbia
Keyword(s):  
Raman Scattering ◽  
Point Of Care ◽  
Simultaneous Detection ◽  
Surface Enhanced Raman Scattering ◽  
Diagnostic Methods ◽  
Current Standard ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Sers Sensing

The ability to accurately diagnose at the point of care is crucial in many pathologies. However, current standard diagnostic practices can only be performed in specialized health or laboratory settings. To move diagnostic methods from a specialized lab to the point of care many alternate methods have been developed and proposed. Among them surface-enhanced Raman scattering (SERS) sensing offers advantageous features, such as simultaneous detection of multiple biotargets and increased accuracy. Many groups have been working towards the translation of SERS sensing methods from the lab to the point of need. In this mini review, we discuss interesting and recent developments in this effort, focusing on how different sensing mechanism can be used in point-of-care testing applications of SERS.

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