High resolution scanning near field mapping of enhancement on SERS substrates: comparison with photoemission electron microscopy

2016 ◽  
Vol 18 (14) ◽  
pp. 9405-9411 ◽  
Author(s):  
C. Awada ◽  
J. Plathier ◽  
C. Dab ◽  
F. Charra ◽  
L. Douillard ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
High Resolution ◽  
Near Field ◽  
Spectroscopic Technique ◽  
Proof Of Concept ◽  
Sers Substrates ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Photoemission Electron

The need for a dedicated spectroscopic technique with nanoscale resolution to characterize SERS substrates pushed us to develop a proof of concept of a functionalized tip–surface enhanced Raman scattering (FTERS) technique.

Microplasma synthesized gold nanoparticles for surface enhanced Raman spectroscopic detection of methylene blue

2021 ◽  
Author(s):  
Xuanhe Li ◽  
Liangliang Lin ◽  
Wei-Hung Chiang ◽  
Kuan Chang ◽  
Hujun Xu
Keyword(s):  
Rapid Detection ◽  
Chemical Species ◽  
Spectroscopic Technique ◽  
Trace Level ◽  
Raman Spectroscopic ◽  
Non Invasive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Non Destructive

Surface enhanced Raman scattering (SERS) is a powerful and sensitive spectroscopic technique that allows for rapid detection of trace-level chemical species in a non-invasive and non-destructive manner. In the present...

Bioconjugation of SERS nanotags and increasing the reproducibility of results

2016 ◽  
Vol 18 (1-2) ◽  
Author(s):  
Mohammad Salehi ◽  
Angela Hamann-Steinmeier
Keyword(s):  
Reproducibility Of Results ◽  
Short Review ◽  
Medical Diagnostics ◽  
Spectroscopy Technique ◽  
Sers Substrates ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Target Molecules

AbstractSurface-enhanced Raman scattering (SERS) is a vibrational spectroscopy technique, which is used in the areas of medical diagnostics. This technique use the advantages of biofunctionalized nanoparticles (NPs) for imaging and quantifying of target molecules such as proteins in assays, cells and tissues. The lack of reliability and reproducibility of the results are major challenges in the application of diagnostics based of SERS substrates. The biofunction and success of nanomedical tasks depends on the quality of each involved element like antibodies (IgGs) and nanostructures before, during and after preparation or conjunction with nanoparticles. This short review summarizes current designs of different SERS substrates and highlights the improvement of particularly simple and gentle conjugation methods for targeting research with SERS labels.

scholarly journals Large-Scale Fabrication of Ultrasensitive and Uniform Surface-Enhanced Raman Scattering Substrates for the Trace Detection of Pesticides

Nanomaterials ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. 520 ◽  
Author(s):  
Jia Zhu ◽  
Guanzhou Lin ◽  
Meizhang Wu ◽  
Zhuojie Chen ◽  
Peimin Lu ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Large Scale ◽  
Capillary Flow ◽  
Surface Enhanced Raman Scattering ◽  
Ag Nps ◽  
Uniform Size ◽  
Sers Substrates ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Technology transfer from laboratory into practical application needs to meet the demands of economic viability and operational simplicity. This paper reports a simple and convenient strategy to fabricate large-scale and ultrasensitive surface-enhanced Raman scattering (SERS) substrates. In this strategy, no toxic chemicals or sophisticated instruments are required to fabricate the SERS substrates. On one hand, Ag nanoparticles (NPs) with relatively uniform size were synthesized using the modified Tollens method, which employs an ultra-low concentration of Ag+ and excessive amounts of glucose as a reducing agent. On the other hand, when a drop of the colloidal Ag NPs dries on a horizontal solid surface, the droplet becomes ropy, turns into a layered structure under gravity, and hardens. During evaporation, capillary flow was burdened by viscidity resistance from the ropy glucose solution. Thus, the coffee-ring effect is eliminated, leading to a uniform deposition of Ag NPs. With this method, flat Ag NPs-based SERS active films were formed in array-well plates defined by hole-shaped polydimethylsiloxane (PDMS) structures bonded on glass substrates, which were made for convenient detection. The strong SERS activity of these substrates allowed us to reach detection limits down to 10−14 M of Rhodamine 6 G and 10−10 M of thiram (pesticide).

scholarly journals Improving SERS Detection of Bacillus thuringiensis Using Silver Nanoparticles Reduced with Hydroxylamine and with Citrate Capped Borohydride

2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Hilsamar Félix-Rivera ◽  
Roxannie González ◽  
Gabriela Del Mar Rodríguez ◽  
Oliva M. Primera-Pedrozo ◽  
Carlos Ríos-Velázquez ◽  
...  
Keyword(s):  
Bacillus Thuringiensis ◽  
Surface Charge ◽  
Near Field ◽  
Medical Diagnostics ◽  
Biological Warfare Agents ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Warfare Agents ◽  
Enhanced Raman Scattering

The development of techniques that could be useful in fields other than biological warfare agents countermeasures such as medical diagnostics, industrial microbiology, and environmental applications have become a very important subject of research. Raman spectroscopy can be used in near field or at long distances from the sample to obtain fingerprinting information of chemical composition of microorganisms. In this research, biochemical components of the cell wall and endospores of Bacillus thuringiensis (Bt) were identified by surface-enhanced Raman scattering (SERS) spectroscopy using silver (Ag) nanoparticles (NPs) reduced by hydroxylamine and borohydride capped with sodium citrate. Activation of “hot spots”, aggregation and surface charge modification of the NPs, was studied and optimized to obtain signal enhancements from Bt by SERS. Slight aggregation of the NPs as well as surface charge modification to a more acidic ambient was induced using small-size borohydride-reduced NPs in the form of metallic suspensions aimed at increasing the Ag NP-Bt interactions. Hydroxylamine-reduced NPs required slight aggregation and no pH modifications in order to obtain high spectral quality results in bringing out SERS signatures of Bt.

Target induced aggregation of modified Au@Ag nanoparticles for surface enhanced Raman scattering and its ultrasensitive detection of arsenic(iii) in aqueous solution

RSC Advances ◽  
2015 ◽  
Vol 5 (95) ◽  
pp. 77755-77759 ◽  
Author(s):  
Bo Yang ◽  
Xiaochun Chen ◽  
Renyong Liu ◽  
Bianhua Liu ◽  
Changlong Jiang
Keyword(s):  
Aqueous Solution ◽  
Spectroscopic Technique ◽  
Ultrasensitive Detection ◽  
Selective Detection ◽  
Raman Spectroscopic ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Induced Aggregation

A highly sensitive and selective detection of As(iii) was reported by target induced aggregation of nanoparticles enhanced Raman spectroscopic technique.

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