A highly enantioselective Biginelli reaction using self-assembled methanoproline–thiourea organocatalysts: asymmetric synthesis of 6-isopropyl-3,4-dihydropyrimidines

Zhijun Hang; Jun Zhu; Xiang Lian; Peng Xu; Han Yu; Sheng Han

doi:10.1039/c5cc07880f

A highly enantioselective Biginelli reaction using self-assembled methanoproline–thiourea organocatalysts: asymmetric synthesis of 6-isopropyl-3,4-dihydropyrimidines

Chemical Communications ◽

10.1039/c5cc07880f ◽

2016 ◽

Vol 52 (1) ◽

pp. 80-83 ◽

Cited By ~ 31

Author(s):

Zhijun Hang ◽

Jun Zhu ◽

Xiang Lian ◽

Peng Xu ◽

Han Yu ◽

...

Keyword(s):

Asymmetric Synthesis ◽

Biginelli Reaction ◽

Optically Active ◽

Self Assembled ◽

The Individual

An efficient self-assembled methanoproline–thiourea organocatalyst for the synthesis of optically active 6-isopropyl-3,4-dihydropyrimidines via an asymmetric Biginelli reaction was developed, which is superior to the individual precatalyst.

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ChemInform Abstract: A Highly Enantioselective Biginelli Reaction Using Self-Assembled Methanoproline-Thiourea Organocatalysts: Asymmetric Synthesis of 6-Isopropyl-3,4-dihydropyrimidines.

ChemInform ◽

10.1002/chin.201617174 ◽

2016 ◽

Vol 47 (17) ◽

Author(s):

Zhijun Hang ◽

Jun Zhu ◽

Xiang Lian ◽

Peng Xu ◽

Han Yu ◽

...

Keyword(s):

Asymmetric Synthesis ◽

Biginelli Reaction ◽

Self Assembled

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Correction: A highly enantioselective Biginelli reaction using self-assembled methanoproline–thiourea organocatalysts: asymmetric synthesis of 6-isopropyl-3,4-dihydropyrimidines

Chemical Communications ◽

10.1039/c6cc90042a ◽

2016 ◽

Vol 52 (11) ◽

pp. 2413-2413

Author(s):

Zhijun Hang ◽

Jun Zhu ◽

Xiang Lian ◽

Peng Xu ◽

Han Yu ◽

...

Keyword(s):

Asymmetric Synthesis ◽

Biginelli Reaction ◽

Self Assembled

Correction for ‘A highly enantioselective Biginelli reaction using self-assembled methanoproline–thiourea organocatalysts: asymmetric synthesis of 6-isopropyl-3,4-dihydropyrimidines’ by Zhijun Hang et al., Chem. Commun., 2016, 52, 80–83.

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Asymmetric synthesis of aerothionin, a marine dimeric spiroisoxazoline natural product, employing optically active spiroisoxazoline derivative

Tetrahedron Letters ◽

10.1016/j.tetlet.2005.11.097 ◽

2006 ◽

Vol 47 (5) ◽

pp. 727-731 ◽

Cited By ~ 30

Author(s):

Takahisa Ogamino ◽

Rika Obata ◽

Shigeru Nishiyama

Keyword(s):

Asymmetric Synthesis ◽

Natural Product ◽

Optically Active

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Central–axial–central chirality transfer: asymmetric synthesis of highly substituted indenes bearing a stereogenic quaternary carbon center from optically active propargyl alcohols

Chemical Communications ◽

10.1039/c4cc08034c ◽

2015 ◽

Vol 51 (2) ◽

pp. 380-383 ◽

Cited By ~ 27

Author(s):

Masahiro Egi ◽

Kaori Shimizu ◽

Marin Kamiya ◽

Yuya Ota ◽

Shuji Akai

Keyword(s):

Asymmetric Synthesis ◽

Optically Active ◽

Quaternary Carbon ◽

Chirality Transfer ◽

Propargyl Alcohols

An asymmetric synthesis of highly substituted indenes has been developed via the central–axial–central chirality transfer from optically active propargyl alcohols.

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Asymmetric Synthesis ofα-Methylα-Amino Acids by Diastereoselective Alkylation of Optically Active 6-Isopropyl-3-methyl-2,3—dihydro-6H-1,4-oxazin-2-ones

Angewandte Chemie International Edition in English ◽

10.1002/anie.199709951 ◽

1997 ◽

Vol 36 (9) ◽

pp. 995-997 ◽

Cited By ~ 35

Author(s):

Rafael Chinchilla ◽

Larry R. Falvello ◽

Nuria Galindo ◽

Carmen Nájera

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Optically Active

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ChemInform Abstract: Asymmetric Synthesis of Optically Active Alcohols with Two Chiral Centres from a Racemic Aldehyde by the Selective Addition of Dialkylzinc Reagents Using Chiral Catalysts.

ChemInform ◽

10.1002/chin.199147046 ◽

2010 ◽

Vol 22 (47) ◽

pp. no-no

Author(s):

S. NIWA ◽

T. HATANAKA ◽

K. SOAI

Keyword(s):

Asymmetric Synthesis ◽

Optically Active ◽

Chiral Catalysts ◽

Selective Addition

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Asymmetric synthesis. Production of optically active amino acids by catalytic hydrogenation

Journal of the American Chemical Society ◽

10.1021/ja00461a014 ◽

1977 ◽

Vol 99 (19) ◽

pp. 6262-6267 ◽

Cited By ~ 417

Author(s):

M. D. Fryzuk ◽

B. Bosnich

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Catalytic Hydrogenation ◽

Optically Active

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Asymmetric synthesis of optically active 6-thiaestrogens

Recueil des Travaux Chimiques des Pays-Bas ◽

10.1002/recl.19720910713 ◽

2010 ◽

Vol 91 (7) ◽

pp. 861-868 ◽

Cited By ~ 2

Author(s):

W. M. B. Könst ◽

W. N. Speckamp ◽

H. O. Houwen ◽

H. O. Huisman

Keyword(s):

Asymmetric Synthesis ◽

Optically Active

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ASYMMETRIC SYNTHESIS VIA POLYMER-ATTACHED OPTICALLY ACTIVE CATALYSTS

Annals of the New York Academy of Sciences ◽

10.1111/j.1749-6632.1980.tb53627.x ◽

1980 ◽

Vol 333 (1 Transition Me) ◽

pp. 35-44 ◽

Cited By ~ 10

Author(s):

J. K. Stille ◽

S. J. Fritschel ◽

N. Takaishi ◽

T. Masuda ◽

H. Imai ◽

...

Keyword(s):

Asymmetric Synthesis ◽

Optically Active

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Asymmetric synthesis of optically active lactones from cyclic acid anhydrides using lipase in organic solvents.

Agricultural and Biological Chemistry ◽

10.1271/bbb1961.52.3087 ◽

1988 ◽

Vol 52 (12) ◽

pp. 3087-3092 ◽

Cited By ~ 30

Author(s):

Yukio YAMAMOTO ◽

Kazuyoshi YAMAMOTO ◽

Takaaki NISHIOKA ◽

Jun''ichi ODA

Keyword(s):

Asymmetric Synthesis ◽

Organic Solvents ◽

Optically Active ◽

Cyclic Acid ◽

Acid Anhydrides

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