DNA-caged gold nanoparticles for controlled release of doxorubicin triggered by a DNA enzyme and pH

2015 ◽  
Vol 51 (65) ◽  
pp. 12996-12999 ◽  
Author(s):  
Zi-Mou Zhang ◽  
Peng-Cheng Gao ◽  
Zhi-Fei Wang ◽  
Bai-Wang Sun ◽  
Yong Jiang
Keyword(s):  
Gold Nanoparticles ◽  
Controlled Release ◽  
Self Assembled

DNA polyhedron-caged AuNPs were self-assembled using four-point-star DNAs, with three strands hybridizing to each other and the fourth strand attaching to the AuNPs. The caged AuNPs can act as doxorubicin nanocarriers; a DNA enzyme and pH can trigger controlled release.

Spontaneous desorption of protein from self-assembled monolayer (SAM)-coated gold nanoparticles induced by high temperature

2021 ◽  
Author(s):  
Shuai Wang ◽  
Xinwen Ou ◽  
Ming Yi ◽  
Jingyuan Li
Keyword(s):  
Gold Nanoparticles ◽  
High Temperature ◽  
Controlled Release ◽  
Protein Adsorption ◽  
Protein Drug ◽  
Nonspecific Binding ◽  
Self Assembled Monolayer ◽  
Reversible Process ◽  
Adsorption And Desorption ◽  
Self Assembled

The nonspecific binding of protein with nanomaterial (NM) is a dynamic reversible process including both protein adsorption and desorption parts, which is crucial for controlled release of protein drug loaded...

Controlled release and corrosion protection by self-assembled colloidal particles electrodeposited onto magnesium alloys

2015 ◽  
Vol 3 (8) ◽  
pp. 1667-1676 ◽  
Author(s):  
Jiadi Sun ◽  
Ye Zhu ◽  
Long Meng ◽  
Wei Wei ◽  
Yang Li ◽  
...  
Keyword(s):  
Corrosion Resistance ◽  
Magnesium Alloy ◽  
Controlled Release ◽  
Magnesium Alloys ◽  
Corrosion Protection ◽  
Colloidal Particles ◽  
Self Assembled ◽  
Bioactive Agents

Self-assembled nanoparticles loaded with bioactive agents were electrodeposited to provide the magnesium alloy with controlled release and corrosion resistance properties.

scholarly journals Disulfide-induced self-assembled targets: A novel strategy for the label free colorimetric detection of DNAs/RNAs via unmodified gold nanoparticles

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Ehsan Shokri ◽  
Morteza Hosseini ◽  
Mehdi D. Davari ◽  
Mohammad R. Ganjali ◽  
Maikel P. Peppelenbosch ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Colorimetric Detection ◽  
Label Free ◽  
Self Assembled ◽  
Novel Strategy

scholarly journals Gold Nanoparticles Presenting Hybridized Self-Assembled Aptamers That Exhibit Enhanced Inhibition of Thrombin

2011 ◽  
Vol 123 (33) ◽  
pp. 7802-7807 ◽  
Author(s):  
Yen-Chun Shiang ◽  
Chia-Lun Hsu ◽  
Chih-Ching Huang ◽  
Huan-Tsung Chang
Keyword(s):  
Gold Nanoparticles ◽  
Self Assembled ◽  
Inhibition Of Thrombin

Innenrücktitelbild: In Situ Synthesis of Self-Assembled Gold Nanoparticles on Glass or Silicon Substrates through Reactive Inkjet Printing (Angew. Chem. 2/2014)

2013 ◽  
Vol 126 (2) ◽  
pp. 611-611
Author(s):  
Mutalifu Abulikemu ◽  
Eman Husni Da'as ◽  
Hanna Haverinen ◽  
Dongkyu Cha ◽  
Mohammad Azad Malik ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Inkjet Printing ◽  
In Situ Synthesis ◽  
Silicon Substrates ◽  
Self Assembled

Acetylcholinesterase Biosensor Based on Gold Nanoparticles and Cysteamine Self Assembled Monolayer for Determination of Monocrotophos

2009 ◽  
Vol 9 (4) ◽  
pp. 2368-2373 ◽  
Author(s):  
Dan Du ◽  
Wenjuan Chen ◽  
Jie Cai ◽  
Jianming Zhang ◽  
Haiyang Tu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Self Assembled Monolayer ◽  
Self Assembled

A Self-Assembled DNA Nanostructure as FRET Nanoflare for Intracellular ATP Imaging

2021 ◽  
Author(s):  
Cai Shijun ◽  
Jiaoli Wang ◽  
Jing Li ◽  
Bing Zhou ◽  
Chunmei He ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Dna Nanostructure ◽  
Intracellular Atp ◽  
Self Assembled

Due to the incorporation of gold nanoparticles (AuNPs), the reported AuNP-based FRET nanoflares still have some problems, such as non-negligible cytotoxicity and time-consuming preparation procudure. In this communication, a novel...

scholarly journals Photothermally Controlled Methotrexate Release System Using β-Cyclodextrin and Gold Nanoparticles

Nanomaterials ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. 985
Author(s):  
Nataly Silva ◽  
Ana Riveros ◽  
Nicolás Yutronic ◽  
Erika Lang ◽  
Boris Chornik ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Controlled Release ◽  
Energy Dissipation ◽  
Ternary System ◽  
Cell Viability ◽  
Inclusion Compound ◽  
Chemical Method ◽  
Guest Molecule ◽  
Laser Wavelength ◽  
Local Energy

The inclusion compound (IC) of cyclodextrin (CD) containing the antitumor drug Methotrexate (MTX) as a guest molecule was obtained to increase the solubility of MTX and decrease its inherent toxic effects in nonspecific cells. The IC was conjugated with gold nanoparticles (AuNPs), obtained by a chemical method, creating a ternary intelligent delivery system for MTX molecules, based on the plasmonic properties of the AuNPs. Irradiation of the ternary system, with a laser wavelength tunable with the corresponding surface plasmon of AuNPs, causes local energy dissipation, producing the controlled release of the guest from CD cavities. Finally, cell viability was evaluated using MTS assays for β-CD/MTX and AuNPs + β-CD/MTX samples, with and without irradiation, against HeLa tumor cells. The irradiated sample of the ternary system AuNPs + β-CD/MTX produced a diminution in cell viability attributed to the photothermal release of MTX.

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