A facile formal [2+1] cycloaddition of styrenes with alpha-bromocarbonyls catalyzed by copper: efficient synthesis of donor–acceptor cyclopropanes

2015 ◽  
Vol 51 (64) ◽  
pp. 12843-12846 ◽  
Author(s):  
Takashi Nishikata ◽  
Yushi Noda ◽  
Ryo Fujimoto ◽  
Shingo Ishikawa

The reaction of alpha-bromocarbonyls and styrenes underwent a formal [2+1] cycloaddition to produce donor–acceptor cyclopropanes.

Heterocycles ◽  
2019 ◽  
Vol 99 (1) ◽  
pp. 200
Author(s):  
Srinivasan Chandrasekaran ◽  
Gade Kishore ◽  
Vibha Gautam ◽  
Shrutisagar Dattatraya Haveli

Synthesis ◽  
2019 ◽  
Vol 52 (02) ◽  
pp. 281-289
Author(s):  
Yerin Kim ◽  
Yong Il Kwon ◽  
Sung-Gon Kim

A method for efficient and mild synthesis of diarylmethylamine scaffold, via Lewis acid catalyzed Friedel–Crafts reaction of donor­–acceptor aziridines with N,N-dialkylanilines to afford a biologically important diarylmethylamine derivatives in high yields (up to 88%), is presented. This reaction is suitable for the synthesis of various diarylmethylamine derivatives and has a broad scope for electron-rich arenes, including dimethoxybenzene.


ChemInform ◽  
2003 ◽  
Vol 34 (46) ◽  
Author(s):  
Brian T. Holmes ◽  
William T. Pennington ◽  
Timothy W. Hanks

2002 ◽  
Vol 31 (8) ◽  
pp. 866-867 ◽  
Author(s):  
Takamitsu Fukuda ◽  
Nagao Kobayashi

Synlett ◽  
2021 ◽  
Author(s):  
Daniel B. Werz ◽  
Anu Jacob ◽  
Philip Barkawitz ◽  
Ivan A. Andreev ◽  
Nina K. Ratmanova ◽  
...  

AbstractAn easy and efficient route to obtain 2-amino-4,5-dihydrothiophenes is presented. A formal (3+2)-cycloaddition of donor–acceptor cyclopropanes and ammonium thiocyanate catalyzed by Yb(OTf)3 delivers the desired products in good to excellent yields. A broad range of functional groups is tolerated during this process.


2010 ◽  
Vol 23 (3) ◽  
pp. 337-342 ◽  
Author(s):  
Yongrong Li ◽  
Yong-Kazumi Tsuboi ◽  
Tsuyoshi Michinobu ◽  
Yoshihito Ishida ◽  
Tomoyasu Hirai ◽  
...  

2003 ◽  
Vol 33 (14) ◽  
pp. 2447-2461 ◽  
Author(s):  
Brian T. Holmes ◽  
William T. Pennington ◽  
Timothy W. Hanks

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