Alkyl–aryl ketone synthesis via nickel-catalyzed reductive coupling of alkyl halides with aryl acids and anhydrides

2015 ◽  
Vol 51 (51) ◽  
pp. 10302-10305 ◽  
Author(s):  
Xiao Jia ◽  
Xinghua Zhang ◽  
Qun Qian ◽  
Hegui Gong
Keyword(s):  
Alkyl Halides ◽  
Reductive Coupling ◽  
Alkyl Aryl ◽  
Alkyl Aryl Ketone ◽  
Aryl Ketones ◽  
Efficient Construction ◽  
Aryl Ketone

The efficient construction of alkyl–aryl ketones can be readily achieved from the reductive coupling of unactivated alkyl and 1-glycosyl bromides with 1.5 equiv. of aryl acids and their anhydrides.

Reaction of Isopropylmagnesium Bromide with Alkyl Aryl Ketone

1954 ◽  
Vol 76 (22) ◽  
pp. 5797-5798 ◽  
Author(s):  
B. F. Landrum ◽  
Chas. T. Lester
Keyword(s):  
Alkyl Aryl ◽  
Alkyl Aryl Ketone ◽  
Aryl Ketone

A ruthenium catalyst that does not require an N–H ligand to achieve high enantioselectivity for hydrogenation of an alkyl-aryl ketone

2003 ◽  
pp. 750-751 ◽  
Author(s):  
Carolyn G. Leong ◽  
Okwado M. Akotsi ◽  
Michael J. Ferguson ◽  
Steven H. Bergens
Keyword(s):  
Ruthenium Catalyst ◽  
Alkyl Aryl ◽  
Alkyl Aryl Ketone ◽  
Aryl Ketone
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