A bodipy based dual functional probe for the detection of hydrogen sulfide and H2S induced apoptosis in cellular systems

2015 ◽  
Vol 51 (54) ◽  
pp. 10875-10878 ◽  
Author(s):  
Neha Gupta ◽  
Shahi Imam Reja ◽  
Vandana Bhalla ◽  
Muskan Gupta ◽  
Gurcharan Kaur ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Cellular Systems ◽  
Dual Functional ◽  
Induced Apoptosis ◽  
In Cells

A bodipy based dual functional probe1has been designed and synthesized, which selectively detects H2S as well as monitors H2S induced apoptosis in cells.

Absence of temporal ordering of apoptotic features in heat-shock treated leukemia and lymphoma cell lines

1996 ◽  
Vol 54 ◽  
pp. 758-759
Author(s):  
D. W. Fairbain ◽  
M.D. Standing ◽  
K.L. O'Neill
Keyword(s):  
Heat Shock ◽  
Cell Lines ◽  
Chromatin Condensation ◽  
Membrane Integrity ◽  
Resistant Cell ◽  
Membrane Blebbing ◽  
Late Loss ◽  
Induced Apoptosis ◽  
Dying Cells ◽  
In Cells

Apoptosis is a genetically defined response to physiological stimuli that results in cellular suicide. Features common to apoptotic cells include chromatin condensation, oligonucleosomal DNA fragmentation, membrane blebbing, nuclear destruction, and late loss of ability to exclude vital dyes. These characteristics contrast markedly from pathological necrosis, in which membrane integrity loss is demonstrated early, and other features of apoptosis, which allow a non-inflammatory removal of dead and dying cells, are absent. Using heat shock-induced apoptosis as a model for examining stress response in cells, we undertook to categorize a variety of human leukemias and lymphomas with regard to their response to heat shock. We were also interested in determining whether a common temporal order was followed in cells dying by apoptosis. In addition, based on our previous results, we investigated whether increasing heat load resulted in increased apoptosis, with particular interest in relatively resistant cell lines, or whether the mode of death changed from apoptosis to necrosis.

A NIR fluorescent probe for the detection and visualization of hydrogen sulfide using the aldehyde group assisted thiolysis of dinitrophenyl ether strategy

2018 ◽  
Vol 6 (47) ◽  
pp. 7916-7925 ◽  
Author(s):  
Ming Qian ◽  
Liuwei Zhang ◽  
Zhongji Pu ◽  
Jing Xia ◽  
Lili Chen ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Fluorescent Probe ◽  
Aldehyde Group ◽  
In Cells

A NIR fluorescent probe exploiting the aldehyde group assisted thiolysis of dinitrophenyl ether strategy for H2S imaging in cells, tissues and mice.

Fast and sensitive fluorescent probe for ratiometric detection of hydrogen sulfide in mitochondria

2019 ◽  
Vol 11 (2) ◽  
pp. 232-235 ◽  
Author(s):  
Na Jiang ◽  
Bin Wang ◽  
Tao Liu ◽  
Qingyu Liu ◽  
Qin Wei ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Response Time ◽  
Fluorescent Probe ◽  
High Selectivity ◽  
Fluorescent Dye ◽  
Rapid Response ◽  
Ratiometric Detection ◽  
In Cells

A hemicyanine-based fluorescent dye, Mito-BT, was developed to ratiometrically detect H2S. This dye was of high selectivity, photostability and sensitivity with a rapid response time of 10 seconds. In addition, Mito-BT was localized in mitochondria, making it a promising probe for detecting H2S in cells.

Hydrogen sulfide inhibits MPP+-induced apoptosis in PC12 cells

Life Sciences ◽  
2009 ◽  
Vol 85 (7-8) ◽  
pp. 269-275 ◽  
Author(s):  
Wei-Lan Yin ◽  
Jian-Qin He ◽  
Bi Hu ◽  
Zhi-Sheng Jiang ◽  
Xiao-Qing Tang
Keyword(s):  
Hydrogen Sulfide ◽  
Pc12 Cells ◽  
Induced Apoptosis

scholarly journals Diverse autophagy and apoptosis in myeloid leukemia cells induced by 20(s)-GRh2 and blue LED irradiation

RSC Advances ◽  
2019 ◽  
Vol 9 (67) ◽  
pp. 39124-39132
Author(s):  
Jianjian Zhuang ◽  
Juxin Yin ◽  
Chaojian Xu ◽  
Mengmeng Jiang ◽  
Shaowu Lv
Keyword(s):  
Myeloid Leukemia ◽  
Leukemia Cells ◽  
Blue Led ◽  
Induced Apoptosis ◽  
Led Irradiation ◽  
In Cells

Blue LED and 20(S)-GRh2 induced apoptosis and autophagy in cells.

Expression of Hsf1, Hsf2, and Phlda1 in cells undergoing cryptorchid-induced apoptosis in rat testes

2011 ◽  
Vol 78 (4) ◽  
pp. 283-291 ◽  
Author(s):  
Fang Liu ◽  
Zeng-Lu Xu ◽  
Xiao-Jing Qian ◽  
Wen-Ying Qiu ◽  
Hui Huang
Keyword(s):  
Induced Apoptosis ◽  
In Cells

scholarly journals Acetylation of TIP60 at K104 is essential for metabolic stress-induced apoptosis in cells of hepatocellular cancer

2018 ◽  
Vol 362 (2) ◽  
pp. 279-286 ◽  
Author(s):  
Xiao Fang ◽  
Guojun Lu ◽  
Kyungsoo Ha ◽  
Han Lin ◽  
Ye Du ◽  
...  
Keyword(s):  
Metabolic Stress ◽  
Hepatocellular Cancer ◽  
Induced Apoptosis ◽  
In Cells
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