Cp2TiCl2-catalyzed cis-hydroalumination of propargylic amines with Red-Al: stereoselective synthesis of Z-configured allylic amines

2015 ◽  
Vol 51 (29) ◽  
pp. 6426-6429 ◽  
Author(s):  
Renhong Sun ◽  
Jun Liu ◽  
Shuang Yang ◽  
Ming Chen ◽  
Ning Sun ◽  
...  
Keyword(s):  
Stereoselective Synthesis ◽  
Allylic Amines ◽  
High Stereoselectivity

Titanium-catalyzed cis-hydroalumination of propargylic amines with Red-Al provides Z-configured allylic amines in good to excellent yields with high stereoselectivity.

A simple stereoselective synthesis of primary allylic amines from 4-amino-1-azadienes

1989 ◽  
pp. 1132 ◽  
Author(s):  
Jos� Barluenga ◽  
Enrique Aguilar ◽  
Jes�s Joglar ◽  
Bernardo Olano ◽  
Santos Fustero
Keyword(s):  
Stereoselective Synthesis ◽  
Allylic Amines

ChemInform Abstract: A Simple Stereoselective Synthesis of Primary Allylic Amines from 4-Amino-1-azadienes.

ChemInform ◽  
1990 ◽  
Vol 21 (6) ◽  
Author(s):  
J. BARLUENGA ◽  
E. AGUILAR ◽  
J. JOGLAR ◽  
B. OLANO ◽  
S. FUSTERO
Keyword(s):  
Stereoselective Synthesis ◽  
Allylic Amines

First Application of Ionic Liquid to Reactions Involving Organotellurium Compounds as Intermediates

2005 ◽  
Vol 2005 (7) ◽  
pp. 446-448 ◽  
Author(s):  
Lei Wang ◽  
Zhizhen Huang
Keyword(s):  
Ionic Liquid ◽  
High Purity ◽  
Stereoselective Synthesis ◽  
Condensation Reaction ◽  
Unsaturated Compounds ◽  
Novel Method ◽  
Ionic Solvent ◽  
Organotellurium Compounds ◽  
High Stereoselectivity

The condensation reaction of telluronium salts 1 with aldehydes and dibutyl telluride 4, bromide 5 with aldehyde 2 proceeded smoothly in the ionic solvent [bmim][BF4], affording a novel method for the stereoselective synthesis of (E)-α,β-unsaturated compounds 3 in high purity, excellent yields and high stereoselectivity.

Regio- and Stereoselective Synthesis of Spirooxindoles via Mizoroki–Heck Coupling of Aryl Iodides

Synlett ◽  
2018 ◽  
Vol 30 (01) ◽  
pp. 82-88 ◽  
Author(s):  
Mats Larhed ◽  
Ahmed Adeyemi ◽  
Alexander Wetzel ◽  
Joakim Bergman ◽  
Jonas Brånalt
Keyword(s):  
Stereoselective Synthesis ◽  
Double Bond Position ◽  
Unnatural Amino Acid ◽  
Spiro Compounds ◽  
Amino Acid Derivatives ◽  
Heck Coupling ◽  
Reaction Conditions ◽  
Aryl Iodide ◽  
Aryl Iodides ◽  
High Stereoselectivity

A method for highly regio- and stereoselective intramolecular Mizoroki–Heck 5-exo cyclization of aryl iodides to the corresponding spirooxindoles has been developed. Electron-rich and electron-deficient aryl iodide precursors were selectively ring-closed with high stereoselectivity and good yields. The double-bond position in the cyclopentene ring was controlled by careful choice of reaction conditions. These rare spiro compounds were further functionalized to rigidified unnatural amino acid derivatives by a subsequent gas-free Pd(0)-catalyzed alkoxycarbonylation, followed by selective O- and N-deprotections.

Highly efficient and stereoselective synthesis of (2Z)-2-(halomethyl)alk-2-enoates in acidic ionic liquid

2005 ◽  
Vol 2005 (2) ◽  
pp. 96-98 ◽  
Author(s):  
Taokei Ying ◽  
Weiliang Bao ◽  
Zhonghua Wang ◽  
Yongmin Zhang
Keyword(s):  
Ionic Liquid ◽  
Stereoselective Synthesis ◽  
Hydrogen Sulfate ◽  
Acidic Ionic Liquid ◽  
Highly Efficient ◽  
High Stereoselectivity

NaCl, NaBr and NaI immobilised in 1-butyl-3-methylimidazolinium hydrogen sulfate ([bmim][HSO4]) ionic liquid was found to be an efficient halogenation system for the conversion of Baylis-Hillman adducts, 3-hydroxy-2-methylenealkanoates, into (2Z)-2-(halomethyl)alk-2-enoates. To maintain high stereoselectivity the protocol provides significant improvements over existing procedures.

A Stereoselective Synthesis of 3α-Cholesterylamine

2013 ◽  
Vol 859 ◽  
pp. 345-348
Author(s):  
Xiao Chuan Li ◽  
Shan Shan Gong ◽  
Qi Sun
Keyword(s):  
Reaction Time ◽  
Good Yield ◽  
Stereoselective Synthesis ◽  
Simple Procedure ◽  
Starting Material ◽  
Synthetic Method ◽  
Short Reaction Time ◽  
High Stereoselectivity

A novel and stereoselective synthetic method for the preparation of 3α-cholesterylamine was developed. This method had many features, such as easily accessible cholesterol starting material, high stereoselectivity, simple procedure, short reaction time, and good yield.

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