Water-triggered self-assembly polycondensation for the one-pot synthesis of cyclomatrix polyphosphazene nanoparticles from amino acid ester

2015 ◽  
Vol 51 (39) ◽  
pp. 8373-8376 ◽  
Author(s):  
Zhangjun Huang ◽  
Shuangshuang Chen ◽  
Xuemin Lu ◽  
Qinghua Lu
Keyword(s):  
Amino Acid ◽  
Self Assembly ◽  
Solubility Parameter ◽  
Acid Ester ◽  
Amino Acid Ester ◽  
One Pot ◽  
One Pot Synthesis ◽  
The One

Water-triggered self-assembly polycondensation was proposed for preparation of cyclomatrix polyphosphazene nanoparticles from amino acid ester, and a critical solubility parameter was found to determine whether the nanoparticles were formed.

Polyethylene glycol-bonded triethylammonium l-prolinate: a new biodegradable amino-acid-based ionic liquid for the one-pot synthesis of bis(pyrazolyl)methanes as DNA binding agents

2020 ◽  
Vol 44 (39) ◽  
pp. 16995-17012
Author(s):  
Reza Kordnezhadian ◽  
Mohsen Shekouhy ◽  
Somaye Karimian ◽  
Zohreh Tavaf ◽  
Saeed Malek-Hosseini ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Polyethylene Glycol ◽  
Amino Acid ◽  
Dna Binding ◽  
One Pot ◽  
One Pot Synthesis ◽  
Binding Agents ◽  
Dna Binding Agents ◽  
The One

[PEG-TEA]LP, as a new biodegradable ionic liquid catalyst, was successfully synthesized, characterized, and applied to the one-pot pseudo-five-component synthesis of bis(pyrazolyl)methanes.

Iodine/K2CO3-catalyzed synthesis of multisubstituted pyrrolidine-2-carboxylates via a one-pot reaction between an araldehyde, an amino acid ester, and a chalcone

2019 ◽  
Vol 43 (3-4) ◽  
pp. 90-96
Author(s):  
Yongjian Zhang ◽  
Junyi Su ◽  
Tengfei Lin ◽  
Zhangqi Lin ◽  
Zichun Zhou ◽  
...  
Keyword(s):  
Amino Acid ◽  
Acid Ester ◽  
Amino Acid Ester ◽  
One Pot ◽  
Metal Free ◽  
Simple Operation ◽  
Mild Conditions

A series of more than 20 multisubstituted pyrrolidine-2-carboxylates were synthesized via a one-pot cycloaddition of an araldehyde, an amino acid ester, and a chalcone catalyzed by I2/K2CO3 in tetrahydrofuran at 80 °C. The advantages of this method are readily available starting materials, mild conditions, and simple operation, and it is metal free and yields are good to excellent.

scholarly journals One-pot synthesis of oxidation-sensitive supramolecular gels and vesicles

2021 ◽  
Author(s):  
Aroa Duro-Castano ◽  
Laura Rodriguez-Arco ◽  
Lorena Ruiz-Perez ◽  
Cesare De Pace ◽  
Gabriele Marchello ◽  
...  
Keyword(s):  
Self Assembly ◽  
Biomedical Applications ◽  
Stimuli Responsive ◽  
Sustained Drug Release ◽  
One Pot ◽  
Physiological Conditions ◽  
One Pot Synthesis ◽  
Wide Range ◽  
Spherical Micelles ◽  
The One

Polypeptide-based nanoparticles offer unique advantages from a nanomedicine perspective such as biocompatibility, biodegradability and stimuli-responsive properties to (patho)physiological conditions. Conventionally, self-assembled polypeptide nanostructures are prepared by first synthesizing their constituent amphiphilic polypeptides followed by post-polymerization self-assembly. Herein, we describe the one-pot synthesis of oxidation-sensitive supramolecular micelles and vesicles. This was achieved by polymerization-induced self-assembly (PISA) of the N-carboxyanhydride (NCA) precursor of methionine using polyethylene oxide as stabilizing and hydrophilic block in dimethyl sulfoxide (DMSO). By adjusting the hydrophobic block length and concentration we obtained a range of morphologies from spherical to worm-like micelles, to vesicles. Remarkably, the secondary structure of polypeptides greatly influenced the final morphology of the assemblies. Surprisingly, worm-like micellar morphologies were obtained for a wide range of methionine block lengths and solid contents, with spherical micelles restricted to very short hydrophobic lengths. Worm-like micelles further assembled into oxidation-sensitive, self-standing gels in the reaction pot. Both vesicles and worm-like micelles obtained using this method demonstrated to degrade under controlled oxidant conditions which would expand their biomedical applications such as in sustained drug release or as cellular scaffolds in tissue engineering.

Self-assembly directed synthesis of Au nanorices induced by polyaniline and their enhanced peroxidase-like catalytic properties

2017 ◽  
Vol 5 (30) ◽  
pp. 7465-7471 ◽  
Author(s):  
Wei Song ◽  
Maoqiang Chi ◽  
Mu Gao ◽  
Bing Zhao ◽  
Ce Wang ◽  
...  
Keyword(s):  
Self Assembly ◽  
Catalytic Properties ◽  
One Pot ◽  
One Pot Synthesis ◽  
Directed Synthesis ◽  
The One

We describe a self-assembly directed method that allows the one-pot synthesis of Au/polyaniline nanorices with enhanced peroxidase-like activity.

ChemInform Abstract: One-Pot Process for the Preparation of a β-Alkynyl β-Amino Acid Ester.

ChemInform ◽  
2010 ◽  
Vol 28 (44) ◽  
pp. no-no
Author(s):  
M. L. BOYS ◽  
K. J. CAIN-JANICKI ◽  
W. W. DOUBLEDAY ◽  
P. N. FARID ◽  
M. KAR ◽  
...  
Keyword(s):  
Amino Acid ◽  
Acid Ester ◽  
Amino Acid Ester ◽  
One Pot

One-Pot Process for the Preparation of a β-Alkynyl β-Amino Acid Ester

1997 ◽  
Vol 1 (3) ◽  
pp. 233-239 ◽  
Author(s):  
Mark L. Boys ◽  
Kimberly J. Cain-Janicki ◽  
Wendel W. Doubleday ◽  
Payman N. Farid ◽  
Mangalya Kar ◽  
...  
Keyword(s):  
Amino Acid ◽  
Acid Ester ◽  
Amino Acid Ester ◽  
One Pot
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