Organocatalyzed benzannulation for the construction of diverse anthraquinones and tetracenediones

2015 ◽  
Vol 51 (41) ◽  
pp. 8592-8595 ◽  
Author(s):  
Krishna Bahadur Somai Magar ◽  
Likai Xia ◽  
Yong Rok Lee
Keyword(s):  
One Pot ◽  
Unsaturated Aldehydes ◽  
Excellent Yield ◽  
One Pot Synthesis

An efficient one-pot synthesis of anthraquinones and tetracenediones was achieved by l-proline catalyzed benzannulation of commercially available 1,4-naphthoquinones or 1,4-anthracenedione with a variety of α,β-unsaturated aldehydes in good to excellent yield.

Facile one-pot synthesis of 2,3-dihydro-1H-indolizinium derivatives by rhodium(iii)-catalyzed intramolecular oxidative annulation via C–H activation: application to ficuseptine synthesis

2017 ◽  
Vol 53 (16) ◽  
pp. 2491-2494 ◽  
Author(s):  
Nitinkumar Satyadev Upadhyay ◽  
Jayachandran Jayakumar ◽  
Chien-Hong Cheng
Keyword(s):  
One Pot ◽  
Unsaturated Aldehydes ◽  
One Pot Synthesis

Various substituted indolizidinium, quinolizinium and pyrido[1,2-a]azepinium salts were synthesized from benzaldehydes (α,β-unsaturated aldehydes) and alkyne–amines via Rh-catalyzed C–H activation.

scholarly journals Easy, efficient and versatile one-pot synthesis of Janus-type-substituted fullerenols

2019 ◽  
Vol 15 ◽  
pp. 901-905 ◽  
Author(s):  
Marius Kunkel ◽  
Sebastian Polarz
Keyword(s):  
Primary Amines ◽  
One Pot ◽  
Excellent Yield ◽  
One Pot Synthesis ◽  
Broad Variety ◽  
New Applications ◽  
Hydroxy Groups

An efficient one-pot synthesis for Janus-type fullerenol derivatives and how to characterize them is reported. This synthesis provides access to asymmetrically substituted fullerenol with five substituents on one pole of the fullerene and polyhydroxylation moieties, mostly ether and hydroxy groups, on the rest of the fullerene core. As substituents a broad variety of primary amines can be used to obtain Janus-type amphiphilic fullerenols in good to excellent yield. These fullerenol amphiphiles can serve as suitable precursors for further reactions resulting in new applications for fullerenols.

scholarly journals An Efficient One-Pot Synthesis of 1, 5-Benzodiazepine Derivatives Catalyzed by TBAB under Mild Conditions

2012 ◽  
Vol 9 (1) ◽  
pp. 407-414 ◽  
Author(s):  
Mohammad A. Baseer ◽  
Asgar Jafar Khan
Keyword(s):  
Reaction Time ◽  
Solvent Free ◽  
Ammonium Bromide ◽  
One Pot ◽  
Short Reaction Time ◽  
Mild Conditions ◽  
Excellent Yield ◽  
One Pot Synthesis ◽  
Solvent Free Conditions ◽  
Benzodiazepine Derivatives

2,3-Dihydro-1H-1,5-benzodiazepines were synthesized by reaction ofo-phenylenediamine with ketones (acyclic / cyclic) under solvent free conditions in the presence of tetra butyl ammonium bromide (TBAB) in short reaction time with excellent yield.

Urea–Zinc Chloride Eutectic Mixture-Mediated One-Pot Synthesis of Imidazoles: Efficient and Ecofriendly Access to Trifenagrel

Synlett ◽  
2018 ◽  
Vol 30 (02) ◽  
pp. 225-229 ◽  
Author(s):  
Cristian Ochoa-Puentes ◽  
Natalia Higuera ◽  
Diana Peña-Solórzano
Keyword(s):  
Catalytic Activity ◽  
Aromatic Aldehyde ◽  
Zinc Chloride ◽  
Ammonium Acetate ◽  
Reaction Medium ◽  
Eutectic Mixture ◽  
One Pot ◽  
Dicarbonyl Compound ◽  
Excellent Yield ◽  
One Pot Synthesis

The low-melting mixture urea–ZnCl2 was evaluated as a novel reaction medium for the synthesis of imidazoles. The reaction between a dicarbonyl compound, ammonium acetate, and an aromatic aldehyde is efficiently catalyzed by the eutectic solvent, yielding a wide variety of triaryl-1H-imidazoles or 2-aryl-1H-phenanthro[9,10-d]imidazoles in good to excellent yields. In addition, the eutectic solvent was reused in five cycles without loss of its catalytic activity. This protocol was further explored for the synthesis of the drug trifenagrel, giving an excellent yield.

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