Palladium-catalyzed picolinamide-directed coupling of C(sp2)–H and C(sp2)–H: a straightforward approach to quinolinone and pyridone scaffolds

2015 ◽  
Vol 51 (35) ◽  
pp. 7509-7511 ◽  
Author(s):  
Dengyou Zhang ◽  
Feng Gao ◽  
Yong Nian ◽  
Yu Zhou ◽  
Hualiang Jiang ◽  
...  

An unprecedented palladium-catalyzed picolinamide-directed coupling of C(sp2)–H and C(sp2)–H has been developed with exclusive formation of the six-membered ring heterocyclics – quinolinone and pyridone.

Synthesis ◽  
2019 ◽  
Vol 51 (17) ◽  
pp. 3287-3294
Author(s):  
Antonio Arcadi ◽  
Sandro Cacchi ◽  
Giancarlo Fabrizi ◽  
Andrea Fochetti ◽  
Francesca Ghirga ◽  
...  

A straightforward approach to the synthesis of the challenging 12-arylindolo[1,2-c]quinazolin-6(5H)-ones through the palladium-catalyzed direct arylation of N-benzyl and NH-free [1,2-c]quinazolin-6(5H)-ones with aryl halides is described.


2020 ◽  
Vol 7 (18) ◽  
pp. 2612-2617
Author(s):  
Wenhao Dai ◽  
Chunpu Li ◽  
Yichu Liu ◽  
Xu Han ◽  
Xingjun Li ◽  
...  

An efficient approach to obtain saturated seven-membered ring containing three heteroatoms has been developed by using a palladium-catalyzed [4 + 3] dearomatizing cycloaddition. This approach features mild conditions and good functional group tolerance.


2013 ◽  
Vol 52 (24) ◽  
pp. 6313-6316 ◽  
Author(s):  
Davide Audisio ◽  
Gopinadhanpillai Gopakumar ◽  
Lan-Gui Xie ◽  
Luís G. Alves ◽  
Cornelia Wirtz ◽  
...  

ChemInform ◽  
2016 ◽  
Vol 47 (23) ◽  
Author(s):  
Charles Beromeo Bheeter ◽  
Lu Chen ◽  
Jean-Francois Soule ◽  
Henri Doucet

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