Small interfering RNA delivery by polyethylenimine-functionalised porous silicon nanoparticles

2015 ◽  
Vol 3 (12) ◽  
pp. 1555-1565 ◽  
Author(s):  
M. Hasanzadeh Kafshgari ◽  
M. Alnakhli ◽  
B. Delalat ◽  
S. Apostolou ◽  
F. J. Harding ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Protein Expression ◽  
Resistance Gene ◽  
Small Interfering Rna ◽  
Silicon Nanoparticles ◽  
Chemotherapy Resistance ◽  
Glioblastoma Cells ◽  
Mesoporous Silicon ◽  
Porous Silicon Nanoparticles ◽  
Interfering Rna

Polyethyleneimine-coated mesoporous silicon nanoparticles efficiently deliver siRNA in glioblastoma cells, subsequently reducing the protein expression of a chemotherapy resistance gene by 70% within 72 hours.

scholarly journals Mesoporous silicon nanoparticles for targeted two-photon theranostics of prostate cancer

2016 ◽  
Vol 4 (21) ◽  
pp. 3639-3642 ◽  
Author(s):  
Arnaud Chaix ◽  
Khaled El Cheikh ◽  
Elise Bouffard ◽  
Marie Maynadier ◽  
Dina Aggad ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Porous Silicon ◽  
Cancer Cells ◽  
Silicon Nanoparticles ◽  
Prostate Cancer Cells ◽  
Mesoporous Silicon ◽  
Two Photon ◽  
Porous Silicon Nanoparticles ◽  
Mannose 6 Phosphate

Porous silicon nanoparticles grafted with a mannose-6-phosphate analogue were designed for targeting prostate cancer cells.

Fusogenic porous silicon nanoparticles as a broad-spectrum immunotherapy against bacterial infections

2021 ◽  
Author(s):  
Byungji Kim ◽  
Qinglin Yang ◽  
Leslie W. Chan ◽  
Sangeeta N. Bhatia ◽  
Erkki Ruoslahti ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Broad Spectrum ◽  
Therapeutic Efficacy ◽  
Bacterial Infections ◽  
Silicon Nanoparticles ◽  
First Line ◽  
Gram Positive ◽  
Gram Negative ◽  
Porous Silicon Nanoparticles

RNAi-mediated immunotherapy provided by fusogenic porous silicon nanoparticles demonstrates superior therapeutic efficacy against both Gram-positive and Gram-negative bacterial infections compared with first-line antibiotics.

scholarly journals Tracking the Fate of Porous Silicon Nanoparticles Delivering a Peptide Payload by Intrinsic Photoluminescence Lifetime

2018 ◽  
Vol 30 (35) ◽  
pp. 1802878 ◽  
Author(s):  
Yusung Jin ◽  
Dokyoung Kim ◽  
Hajung Roh ◽  
Sojeong Kim ◽  
Sazid Hussain ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Silicon Nanoparticles ◽  
Porous Silicon Nanoparticles ◽  
Photoluminescence Lifetime

scholarly journals Ex vivo biodistribution of gallium-68-labeled porous silicon nanoparticles

2020 ◽  
Vol 1439 ◽  
pp. 012035
Author(s):  
V K Tishchenko ◽  
V. M. Petriev ◽  
A A Mikhailovskaya ◽  
O A Smoryzanova ◽  
A V Kabashin ◽  
...  
Keyword(s):  
Porous Silicon ◽  
Silicon Nanoparticles ◽  
Ex Vivo ◽  
Porous Silicon Nanoparticles ◽  
Gallium 68 ◽  
Ex Vivo Biodistribution
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