A stability-indicating QTRAP LC-MS/MS method for identification and structural characterization of degradation products of indapamide

Khalid A. M. Attia; Mohamed W. I. Nassar; Mohie M. K. Sharaf El-Din; Ahmad A. A. Mohamad; Mohamed M. Y. Kaddah

doi:10.1039/c5ay03075g

A stability-indicating QTRAP LC-MS/MS method for identification and structural characterization of degradation products of indapamide

Analytical Methods ◽

10.1039/c5ay03075g ◽

2016 ◽

Vol 8 (8) ◽

pp. 1836-1851 ◽

Cited By ~ 5

Author(s):

Khalid A. M. Attia ◽

Mohamed W. I. Nassar ◽

Mohie M. K. Sharaf El-Din ◽

Ahmad A. A. Mohamad ◽

Mohamed M. Y. Kaddah

Keyword(s):

Structural Characterization ◽

Ion Trap ◽

Degradation Products ◽

Linear Ion Trap ◽

Stability Indicating ◽

Quadrupole Linear Ion Trap

A selective and sensitive stability-indicating LC-MS/MS method, operated in ESI and quadrupole linear ion trap (QTRAP) modes, has been developed for the identification and structural characterization of stressed degradation products of indapamide.

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Structural Characterization of Photodegradation Products of Enalapril and Its Metabolite Enalaprilat Obtained under Simulated Environmental Conditions by Hybrid Quadrupole-Linear Ion Trap-MS and Quadrupole-Time-of-Flight-MS

Analytical Chemistry ◽

10.1021/ac070891u ◽

2007 ◽

Vol 79 (21) ◽

pp. 8293-8300 ◽

Cited By ~ 37

Author(s):

Sandra Pérez ◽

Peter Eichhorn ◽

Damià Barceló

Keyword(s):

Structural Characterization ◽

Environmental Conditions ◽

Ion Trap ◽

Time Of Flight ◽

Linear Ion Trap ◽

Photodegradation Products ◽

Quadrupole Linear Ion Trap

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Rapid screening and characterization of drug metabolites using multiple ion monitoring dependent product ion scan and postacquisition data mining on a hybrid triple quadrupole-linear ion trap mass spectrometer

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.4045 ◽

2009 ◽

Vol 23 (11) ◽

pp. 1683-1693 ◽

Cited By ~ 46

Author(s):

Ming Yao ◽

Li Ma ◽

Eva Duchoslav ◽

Mingshe Zhu

Keyword(s):

Data Mining ◽

Ion Trap ◽

Rapid Screening ◽

Linear Ion Trap ◽

Triple Quadrupole ◽

Ion Trap Mass Spectrometer ◽

Quadrupole Linear Ion Trap ◽

Dependent Product ◽

Multiple Ion Monitoring

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Stability-Indicating RP-UPLC Method Development and Validation for the Process Related Impurities of Nebivolol and Structural Characterization of Its Forced Degradation Products by LC-MS/MS

British Journal of Pharmaceutical Research ◽

10.9734/bjpr/2016/31354 ◽

2016 ◽

Vol 14 (6) ◽

pp. 1-13

Author(s):

Prasad Kancherla ◽

Pallavi Alegete ◽

Srinivas Keesari ◽

Bhavyasri Khagga ◽

Sridhar Siddiraju ◽

...

Keyword(s):

Structural Characterization ◽

Method Development ◽

Degradation Products ◽

Forced Degradation ◽

Stability Indicating ◽

Related Impurities ◽

Method Development And Validation ◽

Development And Validation

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Rapid screening and characterization of drug metabolites using a new quadrupole-linear ion trap mass spectrometer

Journal of Mass Spectrometry ◽

10.1002/jms.420 ◽

2003 ◽

Vol 38 (2) ◽

pp. 138-150 ◽

Cited By ~ 101

Author(s):

G�rard Hopfgartner ◽

Christophe Husser ◽

Manfred Zell

Keyword(s):

Mass Spectrometer ◽

Ion Trap ◽

Rapid Screening ◽

Linear Ion Trap ◽

Drug Metabolites ◽

Ion Trap Mass Spectrometer ◽

Quadrupole Linear Ion Trap

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Rapid screening and characterization of drug metabolites using a multiple ion monitoring-dependent MS/MS acquisition method on a hybrid triple quadrupole-linear ion trap mass spectrometer

Journal of Mass Spectrometry ◽

10.1002/jms.1412 ◽

2008 ◽

Vol 43 (10) ◽

pp. 1364-1375 ◽

Cited By ~ 70

Author(s):

Ming Yao ◽

Li Ma ◽

W. Griffith Humphreys ◽

Mingshe Zhu

Keyword(s):

Mass Spectrometer ◽

Ion Trap ◽

Rapid Screening ◽

Linear Ion Trap ◽

Triple Quadrupole ◽

Ion Trap Mass Spectrometer ◽

Quadrupole Linear Ion Trap ◽

Acquisition Method ◽

Multiple Ion Monitoring

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A practical strategy for the characterization of coumarins in Radix Glehniae by liquid chromatography coupled with triple quadrupole-linear ion trap mass spectrometry

Journal of Chromatography A ◽

10.1016/j.chroma.2010.04.076 ◽

2010 ◽

Vol 1217 (27) ◽

pp. 4587-4600 ◽

Cited By ~ 49

Author(s):

Wei Yang ◽

Min Ye ◽

Man Liu ◽

Dezhi Kong ◽

Rui Shi ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Ion Trap ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Triple Quadrupole ◽

Practical Strategy ◽

Quadrupole Linear Ion Trap

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Structural elucidation of stress degradation products of ampicillin sodium by liquid chromatography/hybrid triple quadrupole linear ion trap mass spectrometry and liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.6970 ◽

2014 ◽

Vol 28 (17) ◽

pp. 1929-1936 ◽

Cited By ~ 9

Author(s):

Tao Li ◽

Xuanlin Xu ◽

Shan Fu ◽

Juan Zhang ◽

Kerong Zhang ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Ion Trap ◽

Degradation Products ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Triple Quadrupole ◽

Flight Mass Spectrometry ◽

Stress Degradation ◽

Quadrupole Linear Ion Trap

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Determination and structural characterization of ravidasvir metabolites by liquid chromatography coupled to triple quadrupole linear ion trap mass spectrometry: Application to pharmacokinetics and phase I metabolism in rats

Biomedical Chromatography ◽

10.1002/bmc.5146 ◽

2021 ◽

Author(s):

Mohamed M. Y. Kaddah ◽

Wael Talaat ◽

Maha A. El Demellawy

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Phase I ◽

Ion Trap ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Triple Quadrupole ◽

Quadrupole Linear Ion Trap ◽

Mass Spectrometry Application

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High-Throughput Screening and Characterization of Reactive Metabolites Using Polarity Switching of Hybrid Triple Quadrupole Linear Ion Trap Mass Spectrometry

Analytical Chemistry ◽

10.1021/ac702232r ◽

2008 ◽

Vol 80 (5) ◽

pp. 1788-1799 ◽

Cited By ~ 78

Author(s):

Bo Wen ◽

Li Ma ◽

Sidney D. Nelson ◽

Mingshe Zhu

Keyword(s):

Mass Spectrometry ◽

High Throughput Screening ◽

Ion Trap ◽

Reactive Metabolites ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap ◽

Triple Quadrupole ◽

Polarity Switching ◽

Quadrupole Linear Ion Trap

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Structural characterization of unsaturated glycerophospholipids by multiple-stage linear ion-trap mass spectrometry with electrospray ionization

Journal of the American Society for Mass Spectrometry ◽

10.1016/j.jasms.2008.07.023 ◽

2008 ◽

Vol 19 (11) ◽

pp. 1681-1691 ◽

Cited By ~ 88

Author(s):

Fong-Fu Hsu ◽

John Turk

Keyword(s):

Mass Spectrometry ◽

Electrospray Ionization ◽

Structural Characterization ◽

Ion Trap ◽

Ion Trap Mass Spectrometry ◽

Linear Ion Trap

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