Sensitive and homogenous immunoassay of fumonisin in foods using single molecule fluorescence correlation spectroscopy

2016 ◽  
Vol 8 (6) ◽  
pp. 1333-1338 ◽  
Author(s):  
Yannan Bian ◽  
Xiangyi Huang ◽  
Jicun Ren
Keyword(s):  
Food Safety ◽  
Single Molecule ◽  
Fluorescence Correlation Spectroscopy ◽  
Correlation Spectroscopy ◽  
Sensitive Detection ◽  
Single Molecule Fluorescence ◽  
Chemical Contaminants ◽  
Fluorescence Correlation ◽  
Homogeneous Immunoassay ◽  
Highly Sensitive

In this paper, we reported a homogeneous immunoassay for sensitive detection of FB1in maize using single molecule fluorescence correlation spectroscopy (FCS). Our results demonstrate that the quantitative FCS method is rapid, simple and highly sensitive. It can easily be extended to detect other chemical contaminants for food safety.

A sensitive and microscale method for drug screening combining affinity probes and single molecule fluorescence correlation spectroscopy

The Analyst ◽  
2015 ◽  
Vol 140 (4) ◽  
pp. 1207-1214 ◽  
Author(s):  
Lingao Ruan ◽  
Di Su ◽  
Chang Shao ◽  
Jinjie Wang ◽  
Chaoqing Dong ◽  
...  
Keyword(s):  
Theoretical Model ◽  
Single Molecule ◽  
Drug Screening ◽  
Fluorescence Correlation Spectroscopy ◽  
Screening Method ◽  
Correlation Spectroscopy ◽  
Competitive Reaction ◽  
Single Molecule Fluorescence ◽  
Fluorescence Correlation ◽  
Affinity Probes

The theoretical model of drug screening method based on competitive reaction and fluorescence correlation spectroscopy.

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