Electrochemical detection of DNA by using “Pd/GO label copper stain” for signal amplification

2015 ◽  
Vol 7 (20) ◽  
pp. 8554-8560 ◽  
Author(s):  
Zhifei Wang ◽  
Jingjing Yang ◽  
Yanyun Jiang ◽  
Yuanyin Zhang ◽  
Liming Zhang ◽  
...  
Keyword(s):  
Electrochemical Detection ◽  
Signal Amplification ◽  
Copper Ions ◽  
Metallic Copper ◽  
New Strategy

A new strategy for signal amplification by labeling DNA with Pd/GO nanoparticles, which further act as catalysts to reduce copper ions to metallic copper to enhance the signal, is presented.

Scaling up an electrochemical signal with a catalytic hairpin assembly coupling nanocatalyst label for DNA detection

2015 ◽  
Vol 51 (33) ◽  
pp. 7100-7103 ◽  
Author(s):  
Xu Hun ◽  
Guoliang Xie ◽  
Xiliang Luo
Keyword(s):  
Detection Limit ◽  
Electrochemical Detection ◽  
Signal Amplification ◽  
Dna Detection ◽  
Scaling Up ◽  
Redox Cycling ◽  
New Strategy ◽  
Electrochemical Signal ◽  
Catalytic Hairpin Assembly

A new strategy for the electrochemical detection of DNA based on catalytic hairpin assembly combined with nanocatalyst label-based redox cycling reaction signal amplification. A superior detection limit of 0.3 aM toward DNA was achieved.

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