Label-free microRNA detection based on terbium and duplex-specific nuclease assisted target recycling

The Analyst ◽  
2015 ◽  
Vol 140 (15) ◽  
pp. 5082-5089 ◽  
Author(s):  
Jing Zhang ◽  
Dongzhi Wu ◽  
QiuXiang Chen ◽  
Mei Chen ◽  
Yaokun Xia ◽  
...  

In this paper, we describe a novel label-free fluorescence method for microRNA-21 (miR-21) detection based on terbium (Tb3+) and duplex-specific nuclease (DSN) assisted target recycling.

Author(s):  
Zhenqiang Ning ◽  
Erli Yang ◽  
Yongjun Zheng ◽  
Mengyuan Chen ◽  
Guoqiu Wu ◽  
...  

2014 ◽  
Vol 6 (15) ◽  
pp. 6082-6087 ◽  
Author(s):  
Hui Ma ◽  
Wei Wei ◽  
Qian Lu ◽  
Zhixin Zhou ◽  
Henan Li ◽  
...  

A label-free DNA biosensor with high sensitivity and selectivity is constructed by using DNA–Ag NCs and Exo III-catalyzed target recycling amplification.


2018 ◽  
Vol 20 (2) ◽  
Author(s):  
Anurup Ganguli ◽  
Yoshihiko Watanabe ◽  
Michael T. Hwang ◽  
Jui-Cheng Huang ◽  
Rashid Bashir

2018 ◽  
Vol 54 (62) ◽  
pp. 8602-8605 ◽  
Author(s):  
Zi-yue Wang ◽  
Meng Wang ◽  
Yan Zhang ◽  
Chun-yang Zhang

We develop a label-free fluorescence method for sensitive discrimination of 5-hydroxymethylcytosine (5hmC) and 5-methylcytosine (5mC) by ligation-mediated rolling circle amplification.


RSC Advances ◽  
2019 ◽  
Vol 9 (56) ◽  
pp. 32906-32910 ◽  
Author(s):  
Honghong Wang ◽  
Hui Wang ◽  
Mai Zhang ◽  
Yuting Jia ◽  
Zhengping Li

A label-free fluorescent aptamer-based biosensor is developed for the detection of microRNA by the fluorescence regulation of malachite green.


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