Contribution of Raman spectroscopy in nephrology: a candidate technique to detect hydroxyethyl starch of third generation in osmotic renal lesions

The Analyst ◽  
2015 ◽  
Vol 140 (21) ◽  
pp. 7382-7390 ◽  
Author(s):  
V. Vuiblet ◽  
T. T. Nguyen ◽  
A. Wynckel ◽  
M. Fere ◽  
L. Van-Gulick ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Hydroxyethyl Starch ◽  
Hemodynamic Instability ◽  
Third Generation ◽  
Renal Lesions ◽  
Volume Expander

Raman spectroscopy, a candidate tool for detection of HES, a volume expander administrated after hemodynamic instability, in the kidney.

scholarly journals Protective perioperative strategy using a third generation hydroxyethyl starch during surgery in a murine model of liver reperfusion injury

2011 ◽  
Vol 26 (6) ◽  
pp. 456-462
Author(s):  
Dora Catré ◽  
Maria Francelina Lopes ◽  
Celeste Bento ◽  
António Silvério Cabrita
Keyword(s):  
Reperfusion Injury ◽  
Hydroxyethyl Starch ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Histological Study ◽  
Late Phase ◽  
Phase Response ◽  
Volume Control ◽  
Third Generation ◽  
Hepatic Ischemia

PURPOSE: To investigate whether a third generation colloid, hydroxyethyl starch (HES 130/0.4), used for perioperative fluid therapy, protects the rat liver against the late-phase response of ischemia/reperfusion injury (IRI) and if inhibition of neutrophil hepatic infiltration plays a part in this mechanism. METHODS: Wistar rats were used (8 in each group). Three groups had IRI induced by lobar vascular occlusion (60 minutes) and reperfusion (24 hours) and received HES (13 mL/kg iv), 7.5% saline (HS) (13 mL/kg iv) or no fluid. Three other groups were sham-operated and received the same fluid as the test groups. After 24 hours of reperfusion, blood was drawn for alanine aminotransferase (ALT) quantification and ischemic liver samples were taken for histological study (hematoxylin and eosin and chloroacetate staining of neutrophils). RESULTS: HES treatment attenuated the elevation in serum ALT (P=0.001) and reduced the extent of hepatocellular necrosis (P<0.01) compared with the IRI controls. HES-mediated cytoprotection was associated with a decrease of infiltration of neutrophils in the necrotic areas (P<0.05) compared with the untreated IRI rats, but not with the volume control IRI rats (P>0.05). CONCLUSION: Hydroxyethyl starch suppresses inflammatory response and ameliorates the late-phase response of hepatic ischemia/reperfusion injury.

Characterization of Hydroxyethyl Starch by Polymer Analysis for Use as a Plasma Volume Expander

1993 ◽  
Vol 45 (12) ◽  
pp. 445-450 ◽  
Author(s):  
Werner-Michael Kulicke ◽  
Dierk Roessner ◽  
Wiebke Kull
Keyword(s):  
Hydroxyethyl Starch ◽  
Plasma Volume ◽  
Polymer Analysis ◽  
Plasma Volume Expander ◽  
Volume Expander

The haemostatic effects of hydroxyethyl starch (HES) used as a volume expander

1985 ◽  
Vol 11 (6) ◽  
pp. 300-303 ◽  
Author(s):  
E. Macintyre ◽  
I. J. Mackie ◽  
D. Ho ◽  
J. Tinker ◽  
C. Bullen ◽  
...  
Keyword(s):  
Hydroxyethyl Starch ◽  
Volume Expander

scholarly journals Coagulation, oncotic and haemodilutional effects of a third‐generation hydroxyethyl starch (130/0.4) solution in horses

2014 ◽  
Vol 46 (6) ◽  
pp. 739-744 ◽  
Author(s):  
A. Viljoen ◽  
P. C. Page ◽  
G. T. Fosgate ◽  
M. N. Saulez
Keyword(s):  
Hydroxyethyl Starch ◽  
Third Generation

A Systematic Review of Third-Generation Hydroxyethyl Starch (HES 130/0.4) in Resuscitation

2011 ◽  
Vol 112 (3) ◽  
pp. 635-645 ◽  
Author(s):  
Christiane S. Hartog ◽  
Matthias Kohl ◽  
Konrad Reinhart
Keyword(s):  
Systematic Review ◽  
Hydroxyethyl Starch ◽  
Third Generation
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