An efficient ratiometric fluorescent probe for tracking dynamic changes in lysosomal pH

The Analyst ◽  
2015 ◽  
Vol 140 (16) ◽  
pp. 5563-5569 ◽  
Author(s):  
Qianqian Wang ◽  
Liyi Zhou ◽  
Liping Qiu ◽  
Danqing Lu ◽  
Yongxiang Wu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Dynamic Imaging ◽  
Dynamic Changes ◽  
Lysosomal Ph ◽  
Ph Changes ◽  
Ratiometric Fluorescent Probe

We present a new ESIPT-based ratiometric fluorescent probeFR-Lysfor the dynamic imaging of pH changes in lysosomes.

Lysosomal pH Rise during Heat Shock Monitored by a Lysosome-Targeting Near-Infrared Ratiometric Fluorescent Probe

2014 ◽  
Vol 126 (41) ◽  
pp. 11096-11100 ◽  
Author(s):  
Qiongqiong Wan ◽  
Suming Chen ◽  
Wen Shi ◽  
Lihong Li ◽  
Huimin Ma
Keyword(s):  
Heat Shock ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Lysosomal Ph ◽  
Ratiometric Fluorescent Probe

A tumor-targeting and lysosome-specific two-photon fluorescent probe for imaging pH changes in living cells

2017 ◽  
Vol 5 (5) ◽  
pp. 988-995 ◽  
Author(s):  
Baoli Dong ◽  
Xuezhen Song ◽  
Xiuqi Kong ◽  
Chao Wang ◽  
Nan Zhang ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Fluorescent Probe ◽  
Tumor Targeting ◽  
Living Cells ◽  
Lysosomal Ph ◽  
Ph Changes ◽  
Two Photon

Lysosomal pH is closely related to the metastasis and apoptosis of cancer cells.

scholarly journals Chromis-1, a Ratiometric Fluorescent Probe Optimized for Two-Photon Microscopy Reveals Dynamic Changes in Labile Zn(II) in Differentiating Oligodendrocytes

ACS Sensors ◽  
2018 ◽  
Vol 3 (2) ◽  
pp. 458-467 ◽  
Author(s):  
Daisy Bourassa ◽  
Christopher M. Elitt ◽  
Adam M. McCallum ◽  
S. Sumalekshmy ◽  
Reagan L. McRae ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Dynamic Changes ◽  
Two Photon Microscopy ◽  
Two Photon ◽  
Ratiometric Fluorescent Probe

A Novel Water-soluble Ratiometric Fluorescent Probe Based on FRET for Sensing Lysosomal pH

2016 ◽  
Vol 26 (6) ◽  
pp. 2079-2086 ◽  
Author(s):  
Guang-Jie Song ◽  
Su-Yun Bai ◽  
Jing Luo ◽  
Xiao-Qun Cao ◽  
Bao-Xiang Zhao
Keyword(s):  
Fluorescent Probe ◽  
Water Soluble ◽  
Lysosomal Ph ◽  
Ratiometric Fluorescent Probe

Hemicyanine based naked-eye ratiometric fluorescent probe for monitoring lysosomal pH and its application

2020 ◽  
Vol 227 ◽  
pp. 117767
Author(s):  
Yingying Zhang ◽  
Yanliang Zhao ◽  
Yingnan Wu ◽  
Bing Zhao ◽  
Liyan Wang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Lysosomal Ph ◽  
Naked Eye ◽  
Ratiometric Fluorescent Probe

A ratiometric lysosomal pH probe based on the imidazo[1,5-a]pyridine–rhodamine FRET and ICT system

RSC Advances ◽  
2016 ◽  
Vol 6 (47) ◽  
pp. 41317-41322 ◽  
Author(s):  
Guang-Jie Song ◽  
Su-Yun Bai ◽  
Xi Dai ◽  
Xiao-Qun Cao ◽  
Bao-Xiang Zhao
Keyword(s):  
Fluorescent Probe ◽  
Hela Cells ◽  
Lysosomal Ph ◽  
Ph Probe ◽  
System P ◽  
Ict System ◽  
Low Cytotoxicity ◽  
Ratiometric Fluorescent Probe

A new pH-activatable ratiometric fluorescent probe (RhMP) has been developed based on FRET. This probe displayed good selectivity, and excellent reversibility. In addition, RhMP has low cytotoxicity and has been successfully applied in HeLa cells.

Ratiometric Fluorescent Probe for Lysosomal pH Measurement and Imaging in Living Cells Using Single-Wavelength Excitation

2017 ◽  
Vol 89 (13) ◽  
pp. 7038-7045 ◽  
Author(s):  
Xingjiang Liu ◽  
Yuanan Su ◽  
Huihui Tian ◽  
Lei Yang ◽  
Hongyan Zhang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cells ◽  
Ph Measurement ◽  
Lysosomal Ph ◽  
Ratiometric Fluorescent Probe
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