CuFe2O4 magnetic nanocrystal clusters as a matrix for the analysis of small molecules by negative-ion matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

The Analyst ◽  
2015 ◽  
Vol 140 (15) ◽  
pp. 5287-5294 ◽  
Author(s):  
Zian Lin ◽  
Jiangnan Zheng ◽  
Wei Bian ◽  
Zongwei Cai
Keyword(s):  
Small Molecules ◽  
Laser Desorption ◽  
Negative Ion ◽  
Laser Desorption Ionization ◽  
Ionization Time ◽  
Flight Mass Spectrometry ◽  
High Salt Tolerance ◽  
Magnetic Nanocrystal ◽  
Matrix Assisted Laser ◽  
Matrix Assisted Laser Desorption

CuFe2O4 MNCs were proposed as a new matrix for negative ion MALDI-TOF MS, which exhibited interference-free background, high salt tolerance and good reproducibility for analysis of small molecules.

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