Enzyme-free and label-free signal amplification for monitoring endonuclease activity and inhibition via hybridization chain reaction

The Analyst ◽  
2015 ◽  
Vol 140 (10) ◽  
pp. 3500-3506 ◽  
Author(s):  
Jing Zhang ◽  
Zhilu Shi ◽  
Yan Jin

A facile and sensitive method for studying EcoRI activity and inhibition had been developed based on EcoRI-triggered hybridization chain reaction.

RSC Advances ◽  
2016 ◽  
Vol 6 (44) ◽  
pp. 37681-37688 ◽  
Author(s):  
Yunfang Xiong ◽  
Lin Lin ◽  
Xiaojun Zhang ◽  
Guangfeng Wang

Label-free and efficient ECL strategy for detection of NF-κB based on the HCR signal amplification.


RSC Advances ◽  
2016 ◽  
Vol 6 (62) ◽  
pp. 57502-57506 ◽  
Author(s):  
Lin Liu ◽  
Qing Li ◽  
Li-Juan Tang ◽  
Ru-Qin Yu ◽  
Jian-Hui Jiang

A hybridization chain reaction (HCR) lightened by DNA-stabilized silver nanoclusters (AgNCs) as a label-free and turn on fluorescence platform for nucleic acid assays.


2020 ◽  
Vol 8 (47) ◽  
pp. 10770-10775
Author(s):  
Chao Xing ◽  
Ziyi Chen ◽  
Cheng Zhang ◽  
Jun Wang ◽  
Chunhua Lu

An enzyme-free, single-step and rapid signal amplification DNA circuit was developed by integrating target-directed entropy-driven catalysis and hybridization chain reaction for fluorescence analysis of nucleic acids and small molecules.


Sign in / Sign up

Export Citation Format

Share Document