scholarly journals Highly sensitive and specific detection of E. coli by a SERS nanobiosensor chip utilizing metallic nanosculptured thin films

The Analyst ◽  
2015 ◽  
Vol 140 (9) ◽  
pp. 3201-3209 ◽  
Author(s):  
Sachin K. Srivastava ◽  
Hilla Ben Hamo ◽  
Ariel Kushmaro ◽  
Robert S. Marks ◽  
Christoph Grüner ◽  
...  
Keyword(s):  
Thin Films ◽  
Escherichia Coli ◽  
Raman Spectroscopy ◽  
Concentration Level ◽  
Surface Enhanced Raman Spectroscopy ◽  
Specific Detection ◽  
E Coli ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

A nanobiosensor chip, utilizing surface enhanced Raman spectroscopy on nanosculptured thin films of silver, was shown to detectEscherichia colibacteria down to the concentration level of a single bacterium.

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

Combining vancomycin-modified gold nanorod arrays and colloidal nanoparticles as the sandwich model for discrimination of gram-positive bacteria and their detection via surface-enhanced Raman spectroscopy (SERS)

The Analyst ◽  
2021 ◽  
Author(s):  
Araz Norouz Dizaji ◽  
Nihal Simsek Ozek ◽  
Ferhunde Aysin ◽  
Ayfer Calis ◽  
Asli Yilmaz ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Colloidal Nanoparticles ◽  
Nanorod Arrays ◽  
Gram Positive ◽  
Gram Positive Bacteria ◽  
Sensor Platform ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

This study reports the development of a highly sensitive antibiotic-based discrimination and sensor platform for the detection of gram-positive bacteria through surface-enhanced Raman spectroscopy (SERS). Herein, the combination of gold...

Silver-coated Si nanograss as highly sensitive surface-enhanced Raman spectroscopy substrates

2009 ◽  
Vol 96 (4) ◽  
pp. 793-797 ◽  
Author(s):  
Jing Tang ◽  
Fung Suong Ou ◽  
Huei Pei Kuo ◽  
Min Hu ◽  
William F. Stickle ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Self-assembly of ultrathin gold nanowires and single walled carbon nanotubes as a highly sensitive substrate for surface enhanced Raman spectroscopy

2016 ◽  
Vol 40 (9) ◽  
pp. 7286-7289 ◽  
Author(s):  
Yuanchao Zhang ◽  
Jingquan Liu ◽  
Da Li ◽  
Fuhua Yan ◽  
Xin Wang ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Raman Spectroscopy ◽  
Self Assembly ◽  
Single Walled Carbon Nanotubes ◽  
Surface Enhanced Raman Spectroscopy ◽  
Gold Nanowires ◽  
Highly Sensitive ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Walled Carbon Nanotubes

Self-assembly of ultrathin gold nanowires and single-walled carbon nanotubes as highly sensitive substrates for surface enhanced Raman spectroscopy.

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