Aptamer-functionalized graphene oxide for highly efficient loading and cancer cell-specific delivery of antitumor drug

2014 ◽  
Vol 2 (24) ◽  
pp. 3849-3859 ◽  
Author(s):  
Yimei Lu ◽  
Ping Wu ◽  
Yajing Yin ◽  
Hui Zhang ◽  
Chenxin Cai
Keyword(s):  
Graphene Oxide ◽  
Cancer Cell ◽  
Anticancer Drug ◽  
Delivery System ◽  
Drug Loading ◽  
Functionalized Graphene ◽  
Cell Type ◽  
Functionalized Graphene Oxide ◽  
Cell Type Specific ◽  
Efficient Loading

A novel anticancer drug loading and cell-specific delivery system based on cell-type-specific aptamer-functionalized graphene oxide is reported.

A tumor-targeting drug delivery system based on cyclic NGR-modified, combretastatin A4-loaded, functionalized graphene oxide nanosheets

RSC Advances ◽  
2016 ◽  
Vol 6 (72) ◽  
pp. 68134-68140 ◽  
Author(s):  
Fang Ding ◽  
Fanhong Wu ◽  
Qingqing Tian ◽  
Lingling Guo ◽  
Jing Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Graphene Oxide ◽  
Drug Delivery System ◽  
Delivery System ◽  
Tumor Targeting ◽  
Functionalized Graphene ◽  
Graphene Oxide Nanosheets ◽  
Functionalized Graphene Oxide ◽  
Combretastatin A4

Graphene oxide has shown great potential in drug delivery.

cRGDyK-modified camretastain A4-loaded graphene oxide nanosheets for targeted anticancer drug delivery

RSC Advances ◽  
2015 ◽  
Vol 5 (50) ◽  
pp. 40258-40268 ◽  
Author(s):  
Jing Wang ◽  
Qingqing Tian ◽  
Fang Ding ◽  
Yanyan Yu ◽  
Fanhong Wu
Keyword(s):  
Drug Delivery ◽  
Graphene Oxide ◽  
Anticancer Drug ◽  
Targeted Drug Delivery ◽  
Integrin Expression ◽  
Functionalized Graphene ◽  
Graphene Oxide Nanosheets ◽  
Functionalized Graphene Oxide ◽  
Anticancer Drug Delivery ◽  
Targeted Drug

Functionalized graphene oxide (CGO–cRGDyK/POLO) nanosheets were designed and developed for targeted drug delivery to integrin expression.

Functionalized Graphene Oxide Nanoparticles for Cancer Cell-Specific Delivery of Antitumor Drug

2015 ◽  
Vol 26 (1) ◽  
pp. 128-136 ◽  
Author(s):  
Xubo Zhao ◽  
Liangwei Yang ◽  
Xiaorui Li ◽  
Xu Jia ◽  
Lei Liu ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Cancer Cell ◽  
Antitumor Drug ◽  
Oxide Nanoparticles ◽  
Functionalized Graphene ◽  
Functionalized Graphene Oxide

Single functionalized graphene oxide reconstitutes kinesin mediated intracellular cargo transport and delivers multiple cytoskeleton proteins and therapeutic molecules into the cell

2014 ◽  
Vol 50 (78) ◽  
pp. 11595-11598 ◽  
Author(s):  
Batakrishna Jana ◽  
Atanu Biswas ◽  
Saswat Mohapatra ◽  
Abhijit Saha ◽  
Surajit Ghosh
Keyword(s):  
Graphene Oxide ◽  
Cancer Cell ◽  
Functionalized Graphene ◽  
Functionalized Graphene Oxide ◽  
Cargo Transport ◽  
Therapeutic Molecules

Kinesin-1 mediated intracellular cargo transport is reconstituted using EGFP–Tris-NTA-GO (EGFP–TGO) as cargo. This functionalized nanoparticle can deliver multiple cytoskeleton proteins and antimitotic peptides into the cancer cell.

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