scholarly journals Enhancing in vitro biocompatibility and corrosion protection of organic–inorganic hybrid sol–gel films with nanocrystalline hydroxyapatite

2014 ◽  
Vol 2 (24) ◽  
pp. 3886-3896 ◽  
Author(s):  
A. A. El hadad ◽  
V. Barranco ◽  
A. Jiménez-Morales ◽  
E. Peón ◽  
G. J. Hickman ◽  
...  
Keyword(s):  
Corrosion Protection ◽  
Sol Gel ◽  
Ti6al4v Alloy ◽  
Medical Implants ◽  
Inorganic Hybrid ◽  
In Vitro Biocompatibility ◽  
Nanocrystalline Hydroxyapatite ◽  
P Application ◽  
Sol Gel Films

Application of novel organic–inorganic hybrid sol–gel coatings containing dispersed hydroxyapatite particles improved the biocompatibility and corrosion protection properties of the Ti6Al4V alloy used in medical implants.

scholarly journals Triethylphosphite as a network forming agent enhances in vitro biocompatibility and corrosion protection of hybrid organic–inorganic sol–gel coatings for Ti6Al4V alloys

2014 ◽  
Vol 2 (45) ◽  
pp. 7955-7963 ◽  
Author(s):  
A. A. El hadad ◽  
V. Barranco ◽  
A. Jiménez-Morales ◽  
G. J. Hickman ◽  
J. C. Galván ◽  
...  
Keyword(s):  
Corrosion Protection ◽  
Sol Gel ◽  
Silica Sol ◽  
In Vitro Biocompatibility ◽  
Hybrid Silica

Introduction of phosphorous into hybrid silica sol–gel coatings on Ti6Al4V gives materials demonstrating higher levels of intermolecular condensation and fibrinogen uptake as well as improved in vitro biocompatibility and corrosion protection.

Mechanical properties and in vitro biocompatibility evaluation of TiN/TiO2 coated Ti6Al4V alloy

2020 ◽  
Vol 33 ◽  
pp. 1781-1786 ◽  
Author(s):  
Maria P. Nikolova ◽  
Veselina Nikolova ◽  
Veronika L. Ivanova ◽  
Stefan Valkov ◽  
Peter Petrov ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Ti6al4v Alloy ◽  
In Vitro Biocompatibility

scholarly journals Photo-patternable GeO_2-contained organic-inorganic hybrid sol-gel films for photonic applications

2008 ◽  
Vol 16 (6) ◽  
pp. 3490 ◽  
Author(s):  
Wenxiu Que ◽  
C. Y. Jia ◽  
M. Sun ◽  
Z. Sun ◽  
L. L. Wang ◽  
...  
Keyword(s):  
Sol Gel ◽  
Inorganic Hybrid ◽  
Sol Gel Films

Preliminary testing of silicone-urethane elastomers as substrates in human cell culture

e-Polymers ◽  
2007 ◽  
Vol 7 (1) ◽  
Author(s):  
Malgorzata Lewandowska-Szumieł ◽  
Janusz Kozakiewicz ◽  
Piotr Mrówka ◽  
Agnieszka Jurkowska ◽  
Edyta Sienkiewicz-Łatka ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cell Culture ◽  
Blood Platelets ◽  
Human Fibroblasts ◽  
Medical Implants ◽  
Tissue Engineering Scaffolds ◽  
Xtt Assay ◽  
In Vitro Biocompatibility ◽  
Different Types

AbstractSilicone-urethanes, polymers combining the characteristics of two widely used biomaterials, i.e. polyurethanes and silicones, are highly valued in many applications, including medical implants. To assess properties of these materials in contact with living cells, a set of different silicone-urethane materials, candidates for tissue engineering scaffolds, was synthesized and characterized. Two different oligomeric siloxane diols: Tegomer-2111 (Teg) and KF-6001 (KF), and two different types of diisocyanate, MDI and IPDI, were used in synthesis. Blood platelets adhesion to surfaces of selected materials showed a higher thrombogenicity of material based on Teg. Human fibroblasts were used in in vitro biocompatibility tests. The viability of cells cultured on silicone-urethanes was tested by XTT assay. Teg-based silicone-urethanes showed a significantly higher biocompatibility than those based on KF. Materials based on MDI compared to IPDI were found to be significantly more favoured by cells, not necessarily due to the type of diisocyanate but maybe also because of the necessity of using potentially toxic catalyst which accompanies the use of IPDI. Our studies indicate that silicone-urethanes are potent materials for tissue engineering products development. On the basis of the observations performed in cell culture, Tegomer- 2111 as oligomeric siloxane diol and MDI as diisocyanate are recommended as starting materials for silicone-urethane scaffolds synthesis.

Novel Organic-Inorganic Hybrid Nanoparticles as Non-Viral Gene Vector

2008 ◽  
Vol 47-50 ◽  
pp. 1319-1322
Author(s):  
Yang Zhao ◽  
Pei Yin ◽  
Zu Yong Wang ◽  
Lei Ren ◽  
Qi Qing Zhang
Keyword(s):  
Gene Therapy ◽  
Encapsulation Efficiency ◽  
Sol Gel ◽  
Hybrid Nanoparticles ◽  
Viral Gene ◽  
Gene Vector ◽  
Inorganic Hybrid ◽  
Sol Gel Process ◽  
Gene Vectors

Novel hybrid biomaterial of gelatin-siloxane nanoparticles (GS NPs), with positive surface potential and lower cytotoxicity, was synthesized through a 2-step sol-gel process. The pDNA-GS NPs complex was formulated with high encapsulation efficiency, and exhibited and efficient transfection in vitro. We thus envision that the GS NPs material could serve as non-viral gene vectors for gene therapy.

Development and characterization of novel organic–inorganic hybrid sol–gel films

2014 ◽  
Vol 26 (7) ◽  
pp. 725-733 ◽  
Author(s):  
D. Duraibabu ◽  
T. Ganeshbabu ◽  
P. Saravanan ◽  
S. Ananda Kumar
Keyword(s):  
Sol Gel ◽  
Inorganic Hybrid ◽  
Sol Gel Films
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