Facile preparation of ellipsoid-like MCM-41 with parallel channels along the short axis for drug delivery and assembly of Ag nanoparticles for catalysis

2014 ◽  
Vol 2 (30) ◽  
pp. 11565 ◽  
Author(s):  
Nanjing Hao ◽  
Laifeng Li ◽  
Fangqiong Tang
2019 ◽  
Vol 107 (2) ◽  
pp. 157-164 ◽  
Author(s):  
Yousef Fazaeli ◽  
Mohammad Amin Hosseini ◽  
Mohammadreza Afrasyabi ◽  
Parviz Ashtari

Abstract Silica nanoparticles (SNPs) are known as intrinsic radiolabeling agents and offer a fast and reliable approach to deliver theranostic agents into targeted organs. Radiolabeled amorphous silica nanoparticles are of great interest to radiation oncology communities. In order to improve the performance of these nano materials in cancer diagnosis and treatment, their inherent properties, such as surface area and the ability to accumulate in cancer cells, should be enhanced. Pyridine functionalized mesoporous silica MCM-41 is known as a potential anticancer-drug delivery system with high suface area. In thiswork, in order to produce an image-guided drug delivery system for diagnostic applications, [68Ga] radionuclide was grafted on pyridine functionalized MCM-41. The nanoparticles were assessed with atomic force microscopy (AFM), paper chromatography, X-ray diffraction, FTIR spectroscopy, CHN and TGA/DTA analyses. The pharmacokinetic profile evaluation of the radiolabeled nano silica, [68Ga]-Py-Butyl@MCM-41, was done in Fibrosarcoma tumor-bearing mice. This labeled nanocomposite with appropriate blood circulation in body, high structural stability, high tumor/blood ID/g% ratio and fast excretion from the body can be proposed as an efficient nano engineered composite for upcoming tumor targeting/imaging nanotechnology-based applications.


Author(s):  
Young Hee Kim ◽  
Kyung Ja Kim ◽  
Soo Ryong Kim ◽  
Hyo Won Lee

2018 ◽  
Vol 57 (2) ◽  
pp. 175-182
Author(s):  
E.G. Zemtsova ◽  
A.N. Ponomareva ◽  
A.Y. Arbenin ◽  
V.M. Smirnov

Abstract The important stage of the development of smart material for the target drug delivery is the construction of the magnetic part of this material, including mesoporous silica and magnetic nanoparticles (Fe3O4or Fe0). Such a systemwill allow carry outmagnetic decapsulation (excretion) of drug from smart material using the magnetic field of a given value in the right place of the body. The paper considers the features of synthesis mesoporous silica MCM-41 with various pore diameter (33-51 Å) and synthesis of superparamagnetic nanoparticles of magnetite or metallic iron in the pores of mesoporous silica. The dependence of magnetic properties of nanocomposites MCM-41/Fe0 and MCM-41/Fe3O4 from the pore diameters of MCM-41 templates is studied. It was found that the matrix has a decisive influence on the content of iron or magnetite nanoparticles. The saturation magnetization of the material increases with increasing pore size of the mesoporous matrix. Nanocomposites MCM-41/Fe0 and MCM-41/Fe3O4 exhibit superparamagnetism, that allows them to be used as a magnetic material for targeted drug delivery.


2016 ◽  
Vol 294 (10) ◽  
pp. 1643-1649 ◽  
Author(s):  
Rongli Zhang ◽  
Sheng Xu ◽  
Ye Zhu ◽  
Jing Luo ◽  
Xiaoya Liu ◽  
...  

2016 ◽  
Vol 29 (6) ◽  
pp. 441-445 ◽  
Author(s):  
Kyeng Min Park ◽  
Hyunuk Kim ◽  
James Murray ◽  
Jaehyoung Koo ◽  
Kimoon Kim

2014 ◽  
Vol 200 ◽  
pp. 124-131 ◽  
Author(s):  
Aneesh Mathew ◽  
Surendran Parambadath ◽  
Sung Soo Park ◽  
Chang-Sik Ha

2015 ◽  
Vol 48 (2) ◽  
pp. 203-207 ◽  
Author(s):  
Hironori Izawa ◽  
Keisuke Yamamoto ◽  
Satoshi Yoshihashi ◽  
Shinsuke Ifuku ◽  
Minoru Morimoto ◽  
...  

2017 ◽  
Vol 33 (2) ◽  
pp. 647-653
Author(s):  
Eva M. Barrera-Rendón ◽  
Jaime Jiménez-Becerril ◽  
Genoveva García-Rosales

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