Biological and pharmacological activities of amaryllidaceae alkaloids

RSC Advances ◽  
2015 ◽  
Vol 5 (21) ◽  
pp. 16562-16574 ◽  
Author(s):  
Maomao He ◽  
Chunrong Qu ◽  
Oude Gao ◽  
Xianming Hu ◽  
Xuechuan Hong

This review discusses the recent developments on biological and pharmacological activities of amaryllidaceae alkaloids with IC50or EC50values since 2005, supporting the potential therapeutic possibilities for the use of these compounds.

Molecules ◽  
2019 ◽  
Vol 24 (17) ◽  
pp. 3122 ◽  
Author(s):  
Yan Ren ◽  
Yueping Bai ◽  
Zhidan Zhang ◽  
Wenlong Cai ◽  
Antonio Del Rio Flores

Polysaccharides are ubiquitous biomolecules found in nature that contain various biological and pharmacological activities that are employed in functional foods and therapeutic agents. Natural polysaccharides are obtained mainly by extraction and purification, which may serve as reliable procedures to enhance the quality and the yield of polysaccharide products. Moreover, structural analysis of polysaccharides proves to be promising and crucial for elucidating structure–activity relationships. Therefore, this report summarizes the recent developments and applications in extraction, separation, purification, and structural analysis of polysaccharides of plants and fungi.


ChemInform ◽  
2015 ◽  
Vol 46 (18) ◽  
pp. no-no
Author(s):  
Maomao He ◽  
Chunrong Qu ◽  
Oude Gao ◽  
Xianming Hu ◽  
Xuechuan Hong

2008 ◽  
Vol 8 (4) ◽  
pp. 399-420 ◽  
Author(s):  
Rosa Tundis ◽  
Monica Loizzo ◽  
Federica Menichini ◽  
Giancarlo Statti ◽  
Francesco Menichini

2020 ◽  
Vol 36 (6) ◽  
pp. 1001-1015
Author(s):  
Nadia Ali Ahmed Elkanzi

Nitrogen containing synthetically and biologically important heterocyclic ring system namely pyrimidine possess both biological and pharmacological activities, and defend as aromatic six heterocyclic with 1and 3 nitrogen atom in ring. Preparation of pyrimidine via different methods offer its importance in fields of medicinal chemistry and Chemistry. Pyrimidines and their derivatives act as anti-inflammatory, anti-malaria, anti-tumor, cardiovascular agents, anti-neoplastic, anti-tubercular, anti- HIV, diuretic ,anti-viral, anti-microbial, ,analgesic .This review give light up on biological and pharmacological activities of pyrimidine nucleus.


2021 ◽  
Vol 11 ◽  
Author(s):  
Boniface Pone Kamdem ◽  
Eutrophe Le Doux Kamto ◽  
Hugues Kamdem Paumo ◽  
Lebogang Maureen Katata-Seru ◽  
Dieudonné Emmanuel Pegnyemb ◽  
...  

Background: Dysphania ambrosioides (L.) Mosyakin & Clemants is an aromatic herb native to South America, but also distributed widely throughout Africa and Europe. This plant is traditionally used to treat various ailments including, pain and swellings, flu, parasitic diseases, and as analgesic, antipyretic, and wound healing. Phytochemical analyses of D. ambrosioides revealed the presence of terpenoids, flavonoids, coumarins, fatty acids and miscellaneous compounds among others, which might be responsible for its modern pharmacological actions. Objective: The present work summarizes recent developments on phytochemistry, ethnomedicinal use, pharmacology, and toxicity of D. ambrosioides. A critical assessment of the literature information of D. ambrosioides is also presented. Methods: The available information on D. ambrosioides was collected through libraries and electronic databases [Scifinder, ACS, Scielo, Science direct, Pubmed (National Library of Medicine), Wiley, Springer, PROTA, Web of Science, Google Web, Yahoo search and Google scholar] from respective inception until january 2021. Results: More than 150 compounds, including terpenoids, flavonoids, coumarins, fatty acids, and miscellaneous compounds etc.. were identified from D. ambrosioides. D. ambrosioides exhibited a wide range of pharmacological activities, including antimalarial, anti-inflammatory, antiparasitic, anticancer, insecticidal, antigiardial, among others. Metal nanoparticles synthesized from D. ambrosioides extracts presented enhanced pharmacological activities as compared to the crude plant extracts counterparts. Conclusion: D. ambrosioides is a promising medicinal plant, however, more in vivo experiments, cytotoxicity tests, and mechanisms of actions of its extracts and compounds are recommended to transubstantiate the ethnomedicinal claims of this plant into scientific rationale-based information.


2021 ◽  
Author(s):  
Congjie Pan ◽  
Qiaoqiao Wen ◽  
Longfei Ma ◽  
Xuezhen Qin ◽  
Suxiang Feng

Curcumin, an active ingredient of Curcuma longa, which possesses good biological and pharmacological activities, is effective in treating of many diseases. Developing simple and sensitive methods for detection of curcumin...


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