CuSO4–d-glucose, an inexpensive and eco-efficient catalytic system: direct access to diverse quinolines through modified Friedländer approach involving SNAr/reduction/annulation cascade in one pot

RSC Advances ◽  
2015 ◽  
Vol 5 (10) ◽  
pp. 7654-7660 ◽  
Author(s):  
Namrata Anand ◽  
Tanmoy Chanda ◽  
Suvajit Koley ◽  
Sushobhan Chowdhury ◽  
Maya Shankar Singh
Keyword(s):  
Catalytic System ◽  
Direct Access ◽  
One Pot ◽  
Efficient Approach

A one-pot, efficient approach to quinoline synthesis, directly from 2-bromoaromatic aldehydes/ketones in a H2O–EtOH mixture involving a sequence of SNAr/reduction/annulation cascade using CuSO4-d-glucose, is devised.

scholarly journals Copper-catalyzed CuAAC/intramolecular C–H arylation sequence: Synthesis of annulated 1,2,3-triazoles

2012 ◽  
Vol 8 ◽  
pp. 1771-1777 ◽  
Author(s):  
Rajkumar Jeyachandran ◽  
Harish Kumar Potukuchi ◽  
Lutz Ackermann
Keyword(s):  
Catalytic System ◽  
Cascade Reactions ◽  
Direct Access ◽  
One Pot ◽  
Direct Preparation

Step-economical syntheses of annulated 1,2,3-triazoles were accomplished through copper-catalyzed intramolecular direct arylations in sustainable one-pot reactions. Thus, catalyzed cascade reactions involving [3 + 2]-azide–alkyne cycloadditions (CuAAC) and C–H bond functionalizations provided direct access to fully substituted 1,2,3-triazoles with excellent chemo- and regioselectivities. Likewise, the optimized catalytic system proved applicable to the direct preparation of 1,2-diarylated azoles through a one-pot C–H/N–H arylation reaction.

One-Pot Synthesis and Conformational Analysis of 6-Membered Cyclic Iodonium Salts

2020 ◽  
Author(s):  
Lucien Caspers ◽  
Julian Spils ◽  
Mattis Damrath ◽  
Enno Lork ◽  
Boris Nachtsheim
Keyword(s):  
Conformational Analysis ◽  
Bronsted Acids ◽  
One Pot ◽  
Benzyl Alcohols ◽  
Iodonium Salts ◽  
Efficient Approach ◽  
One Pot Synthesis ◽  
Diaryliodonium Salts

In this article we describe an efficient approach for the synthesis of cyclic diaryliodonium salts. The method is based on benzyl alcohols as starting materials and consists of an Friedel-Crafts-arylation/oxidation sequence. Besides a deep optimization, particluar focusing on the choice and ratios of the utilized Bronsted-acids and oxidants, we explore the substrate scope of this transformation. We also discuss an interesting isomerism of cyclic iodonium salts substituted with aliphatic substituents at the bridge head carbon. <br>

Indium-Catalyzed Direct Conversion of Lactones into Thiolactones and Selenolactones in the Presence of Elemental Sulfur and Selenium

Synthesis ◽  
2017 ◽  
Vol 50 (03) ◽  
pp. 565-574 ◽  
Author(s):  
Norio Sakai ◽  
Shuhei Horikawa ◽  
Yohei Ogiwara
Keyword(s):  
Catalytic System ◽  
Elemental Sulfur ◽  
Direct Conversion ◽  
The Novel ◽  
One Pot

The direct conversion of lactones into thiolactones with elemental sulfur (S8) catalyzed by InCl3/PhSiH3 in a one-pot reaction is described. This catalytic system was successfully applied to the novel preparation of selenolactones from lactones and selenium.

Facile construction of 3-indolochromenes and 3-indoloxanthenes via EDDF catalyzed one-pot three component reactions

2015 ◽  
Vol 39 (8) ◽  
pp. 6253-6260 ◽  
Author(s):  
Anuj Thakur ◽  
P. Linga Reddy ◽  
Mohit Tripathi ◽  
Diwan S. Rawat
Keyword(s):  
Ethylene Glycol ◽  
Catalytic System ◽  
Present Method ◽  
Rapid Synthesis ◽  
One Pot ◽  
By Products

EDDF–ethylene glycol, an ambiphilic catalytic system has been employed for the mild and rapid synthesis of various 3-indolochromenes and 3-indoloxanthenesviaa one-pot MCR. Besides recyclability of the catalyst, the present method circumvents the formation of any by-products.

An efficient approach towards three component coupling of one pot reaction for synthesis of functionalized benzopyrans

2006 ◽  
Vol 43 (6) ◽  
pp. 1691-1693 ◽  
Author(s):  
B. Sunil Kumar ◽  
N. Srinivasulu ◽  
R. H. Udupi ◽  
B. Rajitha ◽  
Y. Thirupathi Reddy ◽  
...  
Keyword(s):  
One Pot ◽  
Efficient Approach ◽  
Three Component Coupling

Cu(II)-Catalyzed [3+2] Annulation of Thioamides with AIBN: Facile Access to Highly Functionalized Thiazolidine-4-ones

Synthesis ◽  
2021 ◽  
Author(s):  
Pragya Pali ◽  
Dhananjay Yadav ◽  
Gaurav Shukla ◽  
Maya Shankar Singh
Keyword(s):  
Double Bond ◽  
Functional Groups ◽  
Dual Role ◽  
Direct Access ◽  
One Pot ◽  
Simple Method ◽  
Two Component ◽  
Thiazolidine Ring ◽  
Coupling Partner

An efficient and versatile copper-catalyzed unprecedented intermolecular radical [3 + 2] annulation of thioamides with azobisisobutyronitrile (AIBN) is described. This two-component one-pot copper(II)-catalyzed transformation has been achieved via cascade formation of C-S/C−N bonds through the cyclization of in situ generated N,S-acetal intermediate from β-ketothioamide. This operationally simple method allows direct access to synthetically demanding thiazolidin-4-ones in good to excellent yields containing diverse functional groups of different electronic and steric nature. Remarkably, the readily available reaction partners, avoidance of expensive/toxic reagents and the gram scale synthesis are additional attributes to this strategy. AIBN here plays a dual role as radical initiator and unusual source of two carbon coupling partner. Notably, the products possess Z-stereochemistry with regard to the exocyclic C=C double bond at the 2-position of the thiazolidine ring.

A one-pot synthesis of benzimidazoles via aerobic oxidative condensation of benzyl alcohols with o-phenylenediamines catalyzed by [MIMPs]+Cl-/NaNO2/TEMPO

2020 ◽  
Vol 44 (9-10) ◽  
pp. 557-565
Author(s):  
Zhenzhen Geng ◽  
Hong-yu Zhang ◽  
Guohui Yin ◽  
Yuecheng Zhang ◽  
Jiquan Zhao
Keyword(s):  
Ionic Liquid ◽  
Catalytic System ◽  
Sodium Nitrite ◽  
High Efficiency ◽  
Oxidative Condensation ◽  
Imidazolium Chloride ◽  
One Pot ◽  
Benzyl Alcohols ◽  
One Pot Synthesis ◽  
The One

The ionic liquid 1-methyl-3-(3-sulfopropyl)imidazolium chloride ([MIMPs]+Cl-) in combination with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) and sodium nitrite (NaNO2) as a catalytic system demonstrates high efficiency in the one-pot two-step aerobic oxidative condensation of benzyl alcohols with 1,2-phenylenediamines to give benzimidazoles. Various benzimidazoles are obtained in good to excellent yields by this strategy.

A weakly basic Co/CeOx catalytic system for one-pot conversion of cellulose to diols: Kungfu on eggs

2019 ◽  
Vol 55 (53) ◽  
pp. 7663-7666 ◽  
Author(s):  
Chuang Li ◽  
Guangyue Xu ◽  
Kui Li ◽  
Chenguang Wang ◽  
Ying Zhang ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Propylene Glycol ◽  
Catalytic System ◽  
One Pot

A weakly basic Co/CeOx catalyst for one-pot humin-free conversion of cellulose to ethylene glycol (EG) and 1,2-propylene glycol (1,2-PG).

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