In vivo pharmacokinetic features and biodistribution of star and rod shaped gold nanoparticles by multispectral optoacoustic tomography

RSC Advances ◽  
2015 ◽  
Vol 5 (10) ◽  
pp. 7529-7538 ◽  
Author(s):  
Jing Wang ◽  
Yadian Xie ◽  
Liming Wang ◽  
Jinglong Tang ◽  
Jiayang Li ◽  
...  

Multispectral optoacoustic tomography (MSOT) provides a real-time monitoring method to evaluate gold nanoparticles' pharmacokinetics and biodistribution.

Head & Neck ◽  
2013 ◽  
Vol 36 (8) ◽  
pp. 1207-1215 ◽  
Author(s):  
Mazen A. Juratli ◽  
Mustafa Sarimollaoglu ◽  
Eric R. Siegel ◽  
Dmitry A. Nedosekin ◽  
Ekaterina I. Galanzha ◽  
...  

2021 ◽  
Vol 900 ◽  
pp. 115674
Author(s):  
Muthaiah Annalakshmi ◽  
Sakthivel Kumaravel ◽  
T.S.T. Balamurugan ◽  
Shen-Ming Chen ◽  
Ju-Liang He

2015 ◽  
Vol 51 (32) ◽  
pp. 6948-6951 ◽  
Author(s):  
Yanfeng Zhang ◽  
Qian Yin ◽  
Jonathan Yen ◽  
Joanne Li ◽  
Hanze Ying ◽  
...  

Anin vitroandin vivodrug-reporting system is developed for real-time monitoring of drug release via the analysis of the concurrently released near-infrared fluorescence dye.


2019 ◽  
Author(s):  
Sebastiano Bariselli ◽  
Nanami Miyazaki ◽  
Alexxai Kravitz

AbstractStimulants are one of the most widely prescribed classes of pharmaceuticals, but it is unclear which brain pathways underlie their therapeutic and adverse actions. Here, with real-time monitoring of circuit plasticity, we demonstrate that psychostimulants strengthen orbitofrontal (OFC) to dorsomedial striatum (DMS) pathway synapses, and increase striatal output in awake mice. In vivo high-frequency stimulation of OFC-DMS pathway blocked stimulant-induced potentiation and the expression of locomotor sensitization, thereby directly linking OFC-DMS plasticity to hyperactivity.


2016 ◽  
Vol 214 (6) ◽  
pp. 649-652 ◽  
Author(s):  
Hema V. Pingali ◽  
Angela K. Hilliker

Translation is carefully regulated to control protein levels and allow quick responses to changes in the environment. Certain questions about translation in vivo have been unattainable until now. In this issue, Pichon et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201605024) describe a new technique to allow real-time monitoring of translation on single mRNAs.


Author(s):  
Zhaijun Lu ◽  
Weijia Huang ◽  
Mu Zhong ◽  
Dongrun Liu ◽  
Tian Li ◽  
...  

Real-time monitoring of overturning coefficients is very important for ensuring the safety of high-speed trains passing through complex terrain sections under strong wind conditions. In recent years, the phenomenon of “car swaying” that occurs when trains pass through the complex terrain has brought new challenges to ensuring the safety and riding comfort of passengers. In China, more and more high-speed trains are facing strong wind environments when running in complex terrain sections. However, due to the limitation of objective conditions, so far, only a few economical and effective methods of measurement have been developed that are suitable for real-time monitoring of the overturning coefficient of commercial vehicles. Therefore, considering the applicability and universality of such a monitoring method, this study presents a method for measuring the overturning coefficient of trains using the primary suspension system under strong winds. A vehicle test was carried out to verify the accuracy of the method. The results show that after correction, the overturning coefficient obtained from the primary suspension system is generally consistent with the overturning coefficient obtained from the instrumented wheelset. The method of measuring the overturning coefficient of trains in strong wind environments with the primary suspension system is, thus, proven feasible.


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