Development of a highly efficient single-mode microwave applicator with a resonant cavity and its application to continuous flow syntheses

RSC Advances ◽  
2015 ◽  
Vol 5 (14) ◽  
pp. 10204-10210 ◽  
Author(s):  
Saori Yokozawa ◽  
Noriyuki Ohneda ◽  
Ken Muramatsu ◽  
Tadashi Okamoto ◽  
Hiromichi Odajima ◽  
...  
Keyword(s):  
Continuous Flow ◽  
Resonant Cavity ◽  
Single Mode ◽  
Alder Reaction ◽  
Diels Alder ◽  
Reaction Products ◽  
Fischer Indole Synthesis ◽  
Diels Alder Reaction ◽  
Microwave Applicator ◽  
Indole Synthesis

A new microwave applicator specifically designed for continuous flow synthesis has been developed and tested in the Fischer indole synthesis and in the Diels–Alder reaction to afford the reaction products at a scale of 100 g h−1.

scholarly journals Diels–Alder reactions of myrcene using intensified continuous-flow reactors

2017 ◽  
Vol 13 ◽  
pp. 120-126 ◽  
Author(s):  
Christian H Hornung ◽  
Miguel Á Álvarez-Diéguez ◽  
Thomas M Kohl ◽  
John Tsanaktsidis
Keyword(s):  
Continuous Flow ◽  
Flow Reactor ◽  
Scale Up ◽  
Reaction Times ◽  
Alder Reaction ◽  
Diels Alder ◽  
Flow Reactors ◽  
Diels Alder Reaction ◽  
Naturally Occurring ◽  
Continuous Flow Reactors

This work describes the Diels–Alder reaction of the naturally occurring substituted butadiene, myrcene, with a range of different naturally occurring and synthetic dienophiles. The synthesis of the Diels–Alder adduct from myrcene and acrylic acid, containing surfactant properties, was scaled-up in a plate-type continuous-flow reactor with a volume of 105 mL to a throughput of 2.79 kg of the final product per day. This continuous-flow approach provides a facile alternative scale-up route to conventional batch processing, and it helps to intensify the synthesis protocol by applying higher reaction temperatures and shorter reaction times.

The Correction on the Structure of Diels-Alder Reaction Products of Furan Derivatives with Maleic Anhydride

Heterocycles ◽  
1978 ◽  
Vol 9 (12) ◽  
pp. 1759 ◽  
Author(s):  
Tetsuji Kametani ◽  
Toshio Suzuki ◽  
Akiko Tomino ◽  
Seiko Kagawa ◽  
Katsuo Unno ◽  
...  
Keyword(s):  
Maleic Anhydride ◽  
Alder Reaction ◽  
Diels Alder ◽  
Reaction Products ◽  
Furan Derivatives ◽  
Diels Alder Reaction
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