A high-density nanowire electrode on paper for biomedical applications

RSC Advances ◽  
2015 ◽  
Vol 5 (12) ◽  
pp. 8680-8687 ◽  
Author(s):  
P. Mostafalu ◽  
S. Sonkusale

Different types of nanowires made from platinum, nickel and copper are fabricated and patterned with microscale resolution on paper substrates and employed for biomedical applications.

2021 ◽  
pp. 51-61
Author(s):  
A. Yu. Vasil'ev ◽  
V. V. Petrovskaya ◽  
E. A. Nichipor ◽  
V. G. Alpatova ◽  
N. N. Potrakhov ◽  
...  

During the course of this experimental study tomograms of extracted teeth were analyzed before and after filling the root canals with an endodontic material and fragments of broken metal instruments for root canal treatment. During the first stage of the experiment, untreated extracted teeth were scanned using conebeam computed tomography and microfocus cone-beam computed tomography. A comparative assessment of capabilities of the two methods of cone-beam computed tomography based on examination of untreated root canals was carried out. The second part of the study is dedicated to visualization of root canals that contain foreign high-density materials.


MRS Advances ◽  
2018 ◽  
Vol 3 (41) ◽  
pp. 2449-2454
Author(s):  
Juan Carlos Martinez Espinosa ◽  
Miguel Jose Yacaman ◽  
German Plascencia Villa ◽  
Victor Hugo Romero Arellano ◽  
Ana Karen Zavala Raya

AbstractDue to its excellent optical properties, gold nanomaterials with anisotropic morphology are playing an important role in biomedical applications, specifically in the use of Surface Enhanced Raman Spectroscopy (SERS) technique for biological assays. In this work, we verified the behavior of the star shape nanoparticle peaks obtained by chemical synthesis (precursor reactant: HAuCl4, cationic surfactant: CTAB) and whose peaks were formed from the different concentrations of gold seeds (55, 65, 75 and 85 ul) which were added to the total solution (5.275 ml). The shape and size of the nanoparticles was verified with a Hitachi S-5500 microscope with a BF & DF SEM / STEM detector, and for the diameter distribution (hydrodynamic) was carried out by the dynamic light distribution technique with a Malvern DLS system Zetasizer Nano ZS. Particle sizes (peak-to-peak considering) were obtained with variations from 107 to 166 nm. The results suggest adding 75 ul of gold seeds to obtain uniform nanostars with well defined peaks. These gold nano-stars could be applied for identification of specific membrane markers for the study of different types of cancer by the SERS technique.


Author(s):  
Akhilesh Kumar Shakya ◽  
Kutty Selva Nandakumar

Evaluation of immuno-modulating properties of nanomaterials is important to develop new potential therapeutics for inflammatory diseases and cancer. Activation and suppressive effects of nanomaterials on immune responses occur through various interactions with different host proteins. They can also be engineered as carriers and/or adjuvants for different proteins or antigens. Particles, emulsions, and tubes/rods are the major formats of nanomaterials currently used in biomedical applications. Sometimes, nanomaterials induce side effects like undesired immunosuppression and toxicities, which are major concerns at present in designing optimal nanotherapeutics. This chapter summarizes different types of nanomaterials and their effect on immune responses.


Author(s):  
Akhilesh Kumar Shakya ◽  
Kutty Selva Nandakumar

Evaluation of immuno-modulating properties of nanomaterials is important to develop new potential therapeutics for inflammatory diseases and cancer. Activation and suppressive effects of nanomaterials on immune responses occur through various interactions with different host proteins. They can also be engineered as carriers and/or adjuvants for different proteins or antigens. Particles, emulsions, and tubes/rods are the major formats of nanomaterials currently used in biomedical applications. Sometimes, nanomaterials induce side effects like undesired immunosuppression and toxicities, which are major concerns at present in designing optimal nanotherapeutics. This chapter summarizes different types of nanomaterials and their effect on immune responses.


2010 ◽  
Vol 40 ◽  
pp. 85-92 ◽  
Author(s):  
Suman Manandhar ◽  
Noriyuki Yasufuku ◽  
Kiyoshi Omine ◽  
Taizo Kobayashi

This paper describes model tests of different types of tapered piles in cohesionless soils. Chromium plated three steel piles, one straight and two taper-shaped piles of same length and pile tip diameters have been executed for pile loading test in a downward frictional mode. Two different types of model grounds have been prepared for the test. Relative densities of 80 % and 60 % have been modeled to penetrate piles in two different types of sands to observe the effectiveness of skin frictions of different types of piles. The response of tapered piles has shown that the skin friction has increased with increasing the tapering angle at normalized settlement ratio of 0.4. High density ground yields higher skin friction when the maximum tapered pile was penetrated. Slightly increased tapering angle of the pile affects remarkably on the skin friction with compared to conventional straight cylindrical pile even at small 0.1 settlement ratios.


Nanomaterials ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 98 ◽  
Author(s):  
Nagendra Kaushik ◽  
Neha Kaushik ◽  
Nguyen Linh ◽  
Bhagirath Ghimire ◽  
Anchalee Pengkit ◽  
...  

Application of plasma medicine has been actively explored during last several years. Treating every type of cancer remains a difficult task for medical personnel due to the wide variety of cancer cell selectivity. Research in advanced plasma physics has led to the development of different types of non-thermal plasma devices, such as plasma jets, and dielectric barrier discharges. Non-thermal plasma generates many charged particles and reactive species when brought into contact with biological samples. The main constituents include reactive nitrogen species, reactive oxygen species, and plasma ultra-violets. These species can be applied to synthesize biologically important nanomaterials or can be used with nanomaterials for various kinds of biomedical applications to improve human health. This review reports recent updates on plasma-based synthesis of biologically important nanomaterials and synergy of plasma with nanomaterials for various kind of biological applications.


2018 ◽  
Vol 175 ◽  
pp. 07019 ◽  
Author(s):  
Yuta Ito ◽  
Jun Nishimura

In application of the complex Langevin method to QCD at high density and low temperature, the singular-drift problem occurs due to the appearance of near-zero eigenvalues of the Dirac operator. In order to avoid this problem, we proposed to de-form the Dirac operator in such a way that the near-zero eigenvalues do not appear and to extrapolate the deformation parameter to zero from the available data points. Here we test three different types of deformation in a simple large-N matrix model, which under-goes an SSB due to the phase of the fermion determinant, and compare them to see the consistency with one another.


Nanomaterials ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 656 ◽  
Author(s):  
Shi Su ◽  
Peter M. Kang

Background: Nanomedicine is a field of science that uses nanoscale materials for the diagnosis and treatment of human disease. It has emerged as an important aspect of the therapeutics, but at the same time, also raises concerns regarding the safety of the nanomaterials involved. Recent applications of functionalized biodegradable nanomaterials have significantly improved the safety profile of nanomedicine. Objective: Our goal is to evaluate different types of biodegradable nanomaterials that have been functionalized for their biomedical applications. Method: In this review, we used PubMed as our literature source and selected recently published studies on biodegradable nanomaterials and their applications in nanomedicine. Results: We found that biodegradable polymers are commonly functionalized for various purposes. Their property of being naturally degraded under biological conditions allows these biodegradable nanomaterials to be used for many biomedical purposes, including bio-imaging, targeted drug delivery, implantation and tissue engineering. The degradability of these nanoparticles can be utilized to control cargo release, by allowing efficient degradation of the nanomaterials at the target site while maintaining nanoparticle integrity at off-target sites. Conclusion: While each biodegradable nanomaterial has its advantages and disadvantages, with careful design and functionalization, biodegradable nanoparticles hold great future in nanomedicine.


Materials ◽  
2020 ◽  
Vol 13 (16) ◽  
pp. 3641
Author(s):  
Beata Kaczmarek ◽  
Olha Mazur

Collagen-based biomaterials constitute one of the most widely studied types of materials for biomedical applications. Low thermal and mechanical parameters are the main disadvantages of such structures. Moreover, they present low stability in the case of degradation by collagenase. To improve the properties of collagen-based materials, different types of cross-linkers have been researched. In recent years, phenolic acids have been studied as collagen modifiers. Mainly, tannic acid has been tested for collagen modification as it interacts with a polymeric chain by strong hydrogen bonds. When compared to pure collagen, such complexes show both antimicrobial activity and improved physicochemical properties. Less research reporting on other phenolic acids has been published. This review is a summary of the present knowledge about phenolic acids (e.g., tannic, ferulic, gallic, and caffeic acid) application as collagen cross-linkers. The studies concerning collagen-based materials with phenolic acids are summarized and discussed.


2012 ◽  
Vol 1 (1) ◽  
pp. 17-29 ◽  
Author(s):  
Giuseppe Lamanna ◽  
Alessia Battigelli ◽  
Cécilia Ménard-Moyon ◽  
Alberto Bianco

AbstractThe increasing importance of nanotechnology in the field of biomedical applications has encouraged the development of new nanomaterials endowed with multiple functions. Novel nanoscale drug delivery systems with diagnostic, imaging and therapeutic properties hold many promises for the treatment of different types of diseases, including cancer, infection and neurodegenerative syndromes. Functionalized carbon nanotubes (CNTs) are one of the most recent type of nanomaterial developed in biomedicine as they can be designed and imparted with multimodal capabilities. Indeed, the possibility of inserting different functionalities on CNTs is opening the possibility to exploit them on new strategies that combine diagnosis with improved therapeutic efficacies. In this review, we describe the different approaches that have been recently developed to generate multifunctionalized CNTs for biomedical applications. In particular, covalent and non-covalent double and triple functionalization methods are discussed, putting in evidence their use in vitro and in vivo and highlighting the advantages and the drawbacks of these new systems. Preclinical studies have demonstrated that multifunctional CNTs are highly promising when combining diagnostic, imaging and therapeutic modalities.


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