Asymmetric allylation of sulfonyl imines catalyzed by in situ generated Cu(ii) complexes of chiral amino alcohol based Schiff bases

RSC Advances ◽  
2014 ◽  
Vol 4 (99) ◽  
pp. 56424-56433 ◽  
Author(s):  
Debashis Ghosh ◽  
Prasanta Kumar Bera ◽  
Manish Kumar ◽  
Sayed H. R. Abdi ◽  
Noor-ul H. Khan ◽  
...  
Keyword(s):  
Schiff Base ◽  
Schiff Bases ◽  
Amino Alcohol ◽  
Enantioselective Synthesis ◽  
Asymmetric Allylation

We have developed a catalytic route for enantioselective synthesis of homoallyl amines through Cu(ii)-Schiff base catalyzed allylation of aryl N-sulfonylimines.

ChemInform Abstract: Asymmetric Allylation of Sulfonyl Imines Catalyzed by in situ Generated Cu(II) Complexes of Chiral Amino Alcohol Based Schiff Bases.

ChemInform ◽  
2015 ◽  
Vol 46 (16) ◽  
pp. no-no
Author(s):  
Debashis Ghosh ◽  
Prasanta Kumar Bera ◽  
Manish Kumar ◽  
Sayed H. R. Abdi ◽  
Noor-ul H. Khan ◽  
...  
Keyword(s):  
Schiff Bases ◽  
Amino Alcohol ◽  
Asymmetric Allylation

scholarly journals Structural Characterization of Heterodinuclear ZnII-LnIII Complexes (Ln = Pr, Nd) with a Ring-Contracted H2valdien-Derived Schiff Base Ligand

2021 ◽  
Author(s):  
Shabana Noor ◽  
Richard Goddard ◽  
Fehmeeda Khatoon ◽  
Sarvendra Kumar ◽  
Rüdiger W. Seidel
Keyword(s):  
Molecular Structure ◽  
Schiff Base ◽  
Structural Characterization ◽  
Schiff Base Ligand ◽  
Crystal And Molecular Structure ◽  
X Ray ◽  
X Ray Crystallography ◽  
Imidazoline Ring

AbstractSynthesis and structural characterization of two heterodinuclear ZnII-LnIII complexes with the formula [ZnLn(HL)(µ-OAc)(NO3)2(H2O)x(MeOH)1-x]NO3 · n H2O · n MeOH [Ln = Pr (1), Nd (2)] and the crystal and molecular structure of [ZnNd(HL)(µ-OAc)(NO3)2(H2O)] [ZnNd(HL)(OAc)(NO3)2(H2O)](NO3)2 · n H2O · n MeOH (3) are reported. The asymmetrical compartmental ligand (E)-2-(1-(2-((2-hydroxy-3-methoxybenzylidene)amino)-ethyl)imidazolidin-2-yl)-6-methoxyphenol (H2L) is formed from N1,N3-bis(3-methoxysalicylidene)diethylenetriamine (H2valdien) through intramolecular aminal formation, resulting in a peripheral imidazoline ring. The structures of 1–3 were revealed by X-ray crystallography. The smaller ZnII ion occupies the inner N2O2 compartment of the ligand, whereas the larger and more oxophilic LnIII ions are found in the outer O2O2’ site. Graphic Abstract Synthesis and structural characterization of two heterodinuclear ZnII-LnIII complexes (Ln = Pr, Nd) bearing an asymmetrical compartmental ligand formed in situ from N1,N3-bis(3-methoxysalicylidene)diethylenetriamine (H2valdien) through intramolecular aminal formation are reported.

A Short Enantioselective Synthesis of (S)-Levetiracetam Through Direct Pd-Catalyzed Asymmetric N-Allylation of Methyl 4-Aminobutyrate

Synlett ◽  
2021 ◽  
Author(s):  
Dominik Albat ◽  
Jörg-Martin Neudörfl ◽  
Hans-Günther Schmalz
Keyword(s):  
Antiepileptic Drug ◽  
Tartaric Acid ◽  
Enantioselective Synthesis

An exceedingly short and enantioselective synthesis of the antiepileptic drug (S)-levetiracetam was elaborated. As the chirogenic key step a Pd-catalyzed asymmetric N-allylation of methyl 4-aminobutyrate was achieved in the presence of only 1 mol% of a catalyst prepared in situ from [Pd(allyl)Cl]2 and the tartaric acid-derived C2-symmetric diphosphane ligand (S,S)-iPr-MediPhos).

scholarly journals Synthesis and Evaluation of Schiff Bases of 4-Amino-5-(chlorine substituted phenyl)-4H-1,2,4-triazole-3-thione as Antimicrobial Agents

2020 ◽  
Vol 41 (1) ◽  
pp. 26-35
Author(s):  
Kishor Devkota ◽  
Govinda Pathak ◽  
Bhushan Shakya
Keyword(s):  
Schiff Base ◽  
Schiff Bases ◽  
Antimicrobial Agents ◽  
Triazole Ring ◽  
Antimicrobial Activities ◽  
Biologically Active ◽  
Spectral Techniques ◽  
Schiff Base Derivatives ◽  
Bacteria And Fungi ◽  
Different Strains

Triazole ring system has attracted a continuously growing interest of synthetic organic chemists and those dealing with the medicinal compounds due to its versatile potential to interact with biological systems. Schiff bases are also considered as one of the most biologically active compounds.  The aim of the present study was to synthesize new Schiff bases bearing triazole nucleus and to assess their antimicrobial activities. Four new Schiff base derivatives of 1,2,4-triazole-3-thione were synthesized by combining two different pharmacophores viz. triazole nucleus and Schiff base moiety and were characterized by spectral techniques (UV, FT-IR, and NMR). The Schiff bases were evaluated for antibacterial (Staphylococcus aureus, Escherichia coli, and Klebsiella pneumoniae) and antifungal (Candida albicans) activities. The synthesized compounds exhibited good to moderate activities against different strains of bacteria and fungi tested.

Syntheses, Spectroscopy And Crystal Structures Of (R)-N-(1-Aryl-Ethyl)Salicylaldimines And [Rh{(R)-N-(1-Aryl-Ethyl)Salicylaldiminato}(η4-Cod)] Complexes

2007 ◽  
Vol 62 (6) ◽  
pp. 807-817 ◽  
Author(s):  
Mohammed Enamullah ◽  
A.K.M. Royhan Uddin ◽  
Anne-Christine Chamayou ◽  
Christoph Janiak
Keyword(s):  
Mass Spectrometry ◽  
Schiff Base ◽  
Schiff Bases ◽  
Structure Determination ◽  
Chelate Ring ◽  
Optical Rotation ◽  
X Ray ◽  
Mononuclear Complexes ◽  
Chiral Schiff Base ◽  
C Nmr

Condensation of salicylaldehyde with enantiopure (R)-(1-aryl-ethyl)amines yields the enantiopure Schiff bases (R)-N-(1-aryl-ethyl)salicylaldimine (HSB*; aryl = phenyl, 2-methoxyphenyl, 3- methoxyphenyl, 4-methoxyphenyl (4), 4-bromophenyl (5), 2-naphthyl). These Schiff bases readily react with dinuclear (acetato)(η4-cycloocta-1,5-diene)rhodium(I), [Rh(μ-O2CMe)(η4-cod)]2, to afford the mononuclear complexes, cyclooctadiene-((R)-N-(1-aryl-ethyl)salicylaldiminato-κ2N,O)- rhodium(I), [Rh(SB∗)(η4-cod)] (SB* = deprotonated chiral Schiff base = salicylaldiminate; aryl = phenyl (7), 2-methoxyphenyl, 4-methoxyphenyl, 4-bromophenyl, 2-naphthyl). The complexes have been characterized by IR, UV/vis, 1H/13C NMR and mass spectrometry, optical rotation as well as by single-crystal X-ray structure determination for 4, 5 and 7. The structure of 5 shows C-Br· · ·π contacts. Compound 7 is only the second example of a Rh(η4-cod) complex with a six-membered Rh-N,O-chelate ring

scholarly journals Fabrication of injectable hydrogels based on poly(l-glutamic acid) and chitosan

RSC Advances ◽  
2017 ◽  
Vol 7 (28) ◽  
pp. 17005-17019 ◽  
Author(s):  
Shifeng Yan ◽  
Taotao Wang ◽  
Xing Li ◽  
Yuhang Jian ◽  
Kunxi Zhang ◽  
...  
Keyword(s):  
Schiff Base ◽  
Glutamic Acid ◽  
Crosslinking Reaction ◽  
Injectable Hydrogels ◽  
Oppositely Charged

The in situ forming hydrogels based on oppositely charged poly(l-glutamic acid) (PLGA) and chitosan (CS) were prepared via a Schiff base crosslinking reaction.

Enantioselective synthesis of α,α-difluoro-β-lactams using amino alcohol ligands

2014 ◽  
Vol 12 (33) ◽  
pp. 6484-6489 ◽  
Author(s):  
Atsushi Tarui ◽  
Takeshi Ikebata ◽  
Kazuyuki Sato ◽  
Masaaki Omote ◽  
Akira Ando
Keyword(s):  
Amino Alcohol ◽  
Enantioselective Synthesis ◽  
Reformatsky Reaction

A practical and highly enantioselective Reformatsky reaction of ethyl bromodifluoroacetate with imines using a cheap and commercially available amino alcohol ligand is described.

Notizen: Magnetic Studies on Schiff Base Complexes of Al(III) and Si(IV)

1974 ◽  
Vol 29 (7-8) ◽  
pp. 565-566 ◽  
Author(s):  
R. N. Prasad ◽  
J. P. Tandon
Keyword(s):  
Schiff Base ◽  
Schiff Bases ◽  
Schiff Base Complexes ◽  
Magnetic Studies ◽  
Magnetic Susceptibilities

The magnetic susceptibilities of some newly syntesized Al(III) and Si(IV) complexes of Schiff bases derived from the condensation of o-hydroxyacetophenone or 2-dydroxy-1-naphthaldehyde with hydroxyalkylamines or diamines have been measured and the data indicate their diamagnetic character.

Schiff Bases and Related Substances. III. Acetylation of a Schiff Base-Thiol Adduct1

1958 ◽  
Vol 80 (13) ◽  
pp. 3475-3478 ◽  
Author(s):  
Gardner W. Stacy ◽  
Richard I. Day ◽  
Richard J. Morath
Keyword(s):  
Schiff Base ◽  
Schiff Bases ◽  
Related Substances
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