Ligase-assisted, upconversion luminescence resonance energy transfer-based method for specific and sensitive detection of V600E mutation in the BRAF gene

RSC Advances ◽  
2014 ◽  
Vol 4 (99) ◽  
pp. 56235-56240 ◽  
Author(s):  
Peng Wang ◽  
Peng Zhang

We report a specific and sensitive detection of BRAF V600E mutation based on a ligase-assisted signal-amplifiable scheme using upconversion nanoparticles.

2021 ◽  
Vol 7 (9) ◽  
pp. eabe2209
Author(s):  
S. Lamon ◽  
Y. Wu ◽  
Q. Zhang ◽  
X. Liu ◽  
M. Gu

Nanoscale optical writing using far-field super-resolution methods provides an unprecedented approach for high-capacity data storage. However, current nanoscale optical writing methods typically rely on photoinitiation and photoinhibition with high beam intensity, high energy consumption, and short device life span. We demonstrate a simple and broadly applicable method based on resonance energy transfer from lanthanide-doped upconversion nanoparticles to graphene oxide for nanoscale optical writing. The transfer of high-energy quanta from upconversion nanoparticles induces a localized chemical reduction in graphene oxide flakes for optical writing, with a lateral feature size of ~50 nm (1/20th of the wavelength) under an inhibition intensity of 11.25 MW cm−2. Upconversion resonance energy transfer may enable next-generation optical data storage with high capacity and low energy consumption, while offering a powerful tool for energy-efficient nanofabrication of flexible electronic devices.


2020 ◽  
Vol 575 ◽  
pp. 119-129 ◽  
Author(s):  
Diego Mendez-Gonzalez ◽  
Oscar G. Calderón ◽  
Sonia Melle ◽  
Jesús González-Izquierdo ◽  
Luis Bañares ◽  
...  

2010 ◽  
Vol 46 (43) ◽  
pp. 8285 ◽  
Author(s):  
Ping Ping Hu ◽  
Li Qiang Chen ◽  
Chun Liu ◽  
Shu Jun Zhen ◽  
Sai Jin Xiao ◽  
...  

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