One-pot synthesis and evaluation of novel 3-aryl-6-ethoxycarbonyl-4-hydroxy-2H-pyran-2-one as a potent cytotoxic agent

RSC Advances ◽  
2014 ◽  
Vol 4 (100) ◽  
pp. 56870-56875 ◽  
Author(s):  
Ganesh Raosaheb Dhage ◽  
Shankar Ramchandra Thopate ◽  
Shefali Nishikant Ramteke ◽  
Prasad Padmakar Kulkarni
Keyword(s):  
Cytotoxic Agents ◽  
Cytotoxic Agent ◽  
One Pot ◽  
Open Chain ◽  
One Pot Synthesis

A series of new open chain analogs of Phelligridin J were synthesized and these compounds were found to be highly potent cytotoxic agents.

Design and one-pot synthesis of new 7-acyl camptothecin derivatives as potent cytotoxic agents

2012 ◽  
Vol 22 (24) ◽  
pp. 7659-7661 ◽  
Author(s):  
Ying-Qian Liu ◽  
Wei Dai ◽  
Chih-Ya Wang ◽  
Susan L. Morris-Natschke ◽  
Xing-Wen Zhou ◽  
...  
Keyword(s):  
Cytotoxic Agents ◽  
One Pot ◽  
One Pot Synthesis

Ultrasound assisted one-pot synthesis of 1,2-diaryl azaindoles via Pd/C-Cu catalysis: Identification of potential cytotoxic agents

2019 ◽  
Vol 60 (52) ◽  
pp. 151326
Author(s):  
Rapolu Venkateshwarlu ◽  
Shambhu Nath Singh ◽  
Vidavalur Siddaiah ◽  
Hindupur Ramamohan ◽  
Rambabu Dandela ◽  
...  
Keyword(s):  
Cytotoxic Agents ◽  
One Pot ◽  
One Pot Synthesis ◽  
Ultrasound Assisted

Pd/C-catalyzed Synthesis of 4-biaryl Substituted 2-amino benzo[h] chromene Derivatives as Potential Cytotoxic Agents

2018 ◽  
Vol 15 (2) ◽  
pp. 160-168 ◽  
Author(s):  
Chekuri Sharmila Rani ◽  
Meda Haritha ◽  
Mandava V. Basaveswara Rao ◽  
Manojit Pal
Keyword(s):  
Cell Lines ◽  
Cancer Cell ◽  
Ultrasound Irradiation ◽  
Cancer Cell Lines ◽  
Cytotoxic Agents ◽  
One Pot ◽  
Design Synthesis ◽  
One Pot Synthesis ◽  
Cancerous Cell ◽  
The One

Background: We report the design, synthesis and evaluation of a series of 4-biaryl substituted 2-amino benzo[h]chromene derivatives as potential cytotoxic agents. Methods: The one-pot synthesis of this class of compounds was carried out under ultrasound irradiation using an MCR involving Pd/C-catalyzed Suzuki-Miyaura coupling as a key step. Result and Conclusion: Several of these compounds showed promising cytotoxicities when tested against cancer cell lines but no or little effects on non-cancerous cell lines.

ChemInform Abstract: One-Pot Synthesis and Evaluation of Novel 3-Aryl-6-ethoxycarbonyl-4-hydroxy-2H-pyran-2-one as a Potent Cytotoxic Agent.

ChemInform ◽  
2015 ◽  
Vol 46 (18) ◽  
pp. no-no
Author(s):  
Ganesh Raosaheb Dhage ◽  
Shankar Ramchandra Thopate ◽  
Shefali Nishikant Ramteke ◽  
Prasad Padmakar Kulkarni
Keyword(s):  
Cytotoxic Agent ◽  
One Pot ◽  
One Pot Synthesis

Assembly of Quinoline, Triazole and Oxime Ether in a Single Molecular Entity: A Greener and One-pot Synthesis of Novel Oximes as Potential Cytotoxic Agents

2016 ◽  
Vol 13 (3) ◽  
pp. 210-219 ◽  
Author(s):  
Koduru Sri Shanthi Praveena ◽  
Edupuganti Veera Venkat Shivaji Ramarao ◽  
Yedla Poornachandra ◽  
Chityal Ganesh Kumar ◽  
Nallapati Suresh Babu ◽  
...  
Keyword(s):  
Cytotoxic Agents ◽  
Molecular Entity ◽  
Oxime Ether ◽  
One Pot ◽  
One Pot Synthesis
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