Green synthesis of anisotropic silver nanoparticles with potent anticancer activity using Taxus baccata extract

RSC Advances ◽  
2014 ◽  
Vol 4 (106) ◽  
pp. 61394-61403 ◽  
Author(s):  
Abolghasem Abbasi Kajani ◽  
Abdol-Khalegh Bordbar ◽  
Sayyed Hamid Zarkesh Esfahani ◽  
Ahmad Reza Khosropour ◽  
Amir Razmjou

Highly stable colloidal silver nanoparticles with potent anticancer activity against MCF-7 cells were synthesized using Taxus baccata extracts.

2012 ◽  
Vol 66 (1) ◽  
pp. 117-120 ◽  
Author(s):  
Majid Darroudi ◽  
Ali Khorsand Zak ◽  
M.R. Muhamad ◽  
N.M. Huang ◽  
Mohammad Hakimi

2021 ◽  
Author(s):  
Mohammad Mousavi-Khattat ◽  
Hamid Nourbakhshan ◽  
Mehrnaz Roumi ◽  
Mahshid Ebrahiminejad ◽  
Yasaman Fazeli ◽  
...  

Abstract Green synthesis methods are environmentally friendly, cost effective and nonhazardous for biomedical applications in comparison with other methods. The aim of the study was green synthesis of silver nanoparticles using medicinal animal dung extract as a reducing, capping and stabilizing agent for the first time among other synthesis methods of silver nanoparticles. Female donkey’s dung was capable to reduce silver ions to nanoparticles and stabilize them. Silver nanoparticles with average sizes of 36 nm were synthesized and characterized by UV-Vis, FT-IR, XRD and TEM. Moreover, synthesized nanoparticles were analyzed in terms of anticancer activity by MTT assay on MCF-7 cell line. UV–Visible spectrophotometer showed an absorbance peak in the range of 414-433 nm. To identify the phytochemical coating of particles, FTIR analysis was used. Transmission electron microscope (TEM) images and X-ray diffraction (XRD) confirmed the formation of small spherical silver nanoparticles. The MTT assay revealed potent anticancer effects of the aqueous extract synthesized nanoparticles on MCF-7 cells, incubated for 24 hours. Based on the current findings, it is strongly believing that the use of donkey’s dung offers large scale production of biocompatible silver nanoparticles that can be suggested to possess valuable anticancer agents against breast cancer cell lines.


Author(s):  
SHARMILA CHANDRAN ◽  
THILAGAVATHY PONNUSAMY ◽  
DINESH BHEEMAN ◽  
RANJITH KUMAR RAJAMANI ◽  
CHANDAR SHEKAR BELLAN

Objective: Synthesize silver nanoparticles using a green synthesis approach and encapsulate silver nanoparticles with a naturally occurring polymer, particularly of an-hydroglucose type, like dextran sulfate sodium salt and to study its anticancer activity. Methods: Green synthesis approach is been employed in the synthesis of silver nanoparticles using Psidium guajava leaf extract. The nanoparticles were then encapsulated with dextran sulfate biopolymer and the nanoparticles were subjected to different characterization techniques. The structure of the synthesized nanoparticles was analyzed using X-ray diffraction analysis, the presence of different functional groups was analyzed by FTIR studies. Size and morphology of the prepared nanoparticles were investigated using FESEM analysis. Anticancer activity of the synthesized nanoparticles was tested against the MCF-cell line. Results: The XRD analysis shows the crystalline nature of the synthesized nanoparticles. The stretching and vibrating modes of different functional groups were confirmed by FTIR result. The SEM image confirmed the presence of spherical shaped nanoparticles and the TEM image confirmed the average size of the particles to be around 24 nm. The Ag-DS NPs showed 91% cell inhibition for the concentration of 100 μg/ml, indicating the cytotoxicity of the nanoparticles against MCF-7 cell line. Conclusion: Dextran sulfate stabilized silver nanoparticles show potent anticancer activity against MCF-7 cell line.


2016 ◽  
Vol 181 ◽  
pp. 173-177 ◽  
Author(s):  
Dao Tri Thuc ◽  
Tran Quang Huy ◽  
Luc Huy Hoang ◽  
Bui Cong Tien ◽  
Pham Van Chung ◽  
...  

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