A highly selective fluorescent probe for fast detection of nitric oxide in aqueous solution

RSC Advances ◽  
2015 ◽  
Vol 5 (18) ◽  
pp. 13307-13310 ◽  
Author(s):  
Chang-Bo Huang ◽  
Junhai Huang ◽  
Lin Xu
Keyword(s):  
Nitric Oxide ◽  
Aqueous Solution ◽  
Fluorescent Probe ◽  
Detection Rate ◽  
Fast Detection

A naphthalimide-based fluorescent probe NPA exhibits fast detection rate for NO was synthesized.

A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells

2012 ◽  
Vol 48 (88) ◽  
pp. 10871 ◽  
Author(s):  
Zheng Xu ◽  
Lin Xu ◽  
Ji Zhou ◽  
Yufang Xu ◽  
Weiping Zhu ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Hydrogen Sulfide ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Fast Detection

A new double-emission fluorescent probe for fast detection of thiophenols in aqueous solution and living cells

Talanta ◽  
2019 ◽  
Vol 197 ◽  
pp. 204-210 ◽  
Author(s):  
Wenjuan Lv ◽  
Yonglei Chen ◽  
Lei Bian ◽  
Xingguo Chen
Keyword(s):  
Aqueous Solution ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Fast Detection

A rhodamine-based fast and selective fluorescent probe for monitoring exogenous and endogenous nitric oxide in live cells

2018 ◽  
Vol 6 (24) ◽  
pp. 4096-4103 ◽  
Author(s):  
Qing Wang ◽  
Xiaojie Jiao ◽  
Chang Liu ◽  
Song He ◽  
Liancheng Zhao ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Fluorescent Probe ◽  
Live Cells ◽  
Fast Detection ◽  
Endogenous Nitric Oxide

A sensitive and selective fluorescent probe for fast detection of nitric oxide was synthesized by grafting a NO-trapper o-phenylenediamine onto a rhodamine fluorophore.

A novel near-infrared fluorescent probe based on isophorone for the bioassay of endogenous cysteine

2021 ◽  
Author(s):  
Hong-Bo Liu ◽  
Hai Xu ◽  
Xin Guo ◽  
Jian Xiao ◽  
Zheng-Hong Cai ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Stokes Shift ◽  
Rapid Identification ◽  
Large Stokes Shift

A near-infrared (NIR) fluorescent probe with a large Stokes shift (143 nm) for the rapid identification of Cys over Hcy and GSH in aqueous solution was developed.

scholarly journals Hydrogen Sulfide Increases Nitric Oxide Production and Subsequent S-Nitrosylation in Endothelial Cells

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Ping-Ho Chen ◽  
Yaw-Syan Fu ◽  
Yun-Ming Wang ◽  
Kun-Han Yang ◽  
Danny Ling Wang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Endothelial Cells ◽  
Hydrogen Sulfide ◽  
Protein Kinase ◽  
Fluorescent Probe ◽  
Acid Methyl Ester ◽  
High Specificity ◽  
Protein S ◽  
No Production ◽  
No Donor

Hydrogen sulfide (H2S) and nitric oxide (NO), two endogenous gaseous molecules in endothelial cells, got increased attention with respect to their protective roles in the cardiovascular system. However, the details of the signaling pathways between H2S and NO in endothelia cells remain unclear. In this study, a treatment with NaHS profoundly increased the expression and the activity of endothelial nitric oxide synthase. Elevated gaseous NO levels were observed by a novel and specific fluorescent probe, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid methyl ester (FA-OMe), and quantified by flow cytometry. Further study indicated an increase of upstream regulator for eNOS activation, AMP-activated protein kinase (AMPK), and protein kinase B (Akt). By using a biotin switch, the level of NO-mediated protein S-nitrosylation was also enhanced. However, with the addition of the NO donor, NOC-18, the expressions of cystathionine-γ-lyase, cystathionine-β-synthase, and 3-mercaptopyruvate sulfurtransferase were not changed. The level of H2S was also monitored by a new designed fluorescent probe, 4-nitro-7-thiocyanatobenz-2-oxa-1,3-diazole (NBD-SCN) with high specificity. Therefore, NO did not reciprocally increase the expression of H2S-generating enzymes and the H2S level. The present study provides an integrated insight of cellular responses to H2S and NO from protein expression to gaseous molecule generation, which indicates the upstream role of H2S in modulating NO production and protein S-nitrosylation.

Chemistry of the Diazeniumdiolates. 2. Kinetics and Mechanism of Dissociation to Nitric Oxide in Aqueous Solution

2001 ◽  
Vol 123 (23) ◽  
pp. 5473-5481 ◽  
Author(s):  
Keith M. Davies ◽  
David A. Wink ◽  
Joseph E. Saavedra ◽  
Larry K. Keefer
Keyword(s):  
Nitric Oxide ◽  
Aqueous Solution ◽  
Kinetics And Mechanism
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