scholarly journals 2,3-Diaryl-substituted indole based COX-2 inhibitors as leads for imaging tracer development

RSC Advances ◽  
2014 ◽  
Vol 4 (73) ◽  
pp. 38726-38742 ◽  
Author(s):  
Markus Laube ◽  
Christoph Tondera ◽  
Sai Kiran Sharma ◽  
Nicole Bechmann ◽  
Franz-Jacob Pietzsch ◽  
...  
Keyword(s):  
Methoxy Group ◽  
Fischer Indole Synthesis ◽  
Cox 2 ◽  
Cox 2 Inhibitors ◽  
Indole Synthesis ◽  
Tracer Development

A series of 2,3-diaryl-substituted indoles containing a fluorine or methoxy group was synthesized via Fischer indole synthesis, McMurry cyclization, or Bischler–Möhlau reaction to identify potential leads for PET radiotracer development.

Induction of gastric lesions by cyclooxygenase (COX-2) inhibitors in the stomach of adjuvant-induced arthritic rats

2001 ◽  
Vol 120 (5) ◽  
pp. A143-A144
Author(s):  
S KATO ◽  
Y OGAWA ◽  
T KUNIKATA ◽  
T WATANABE ◽  
T ARAKAWA ◽  
...  
Keyword(s):  
Gastric Lesions ◽  
Cox 2 ◽  
Cox 2 Inhibitors

Synthesis and Evaluation of Benzimidazole Derivatives as Selective COX-2 Inhibitors

2015 ◽  
Vol 11 (2) ◽  
pp. 188-199 ◽  
Author(s):  
Ankita Rathore ◽  
Mujeeb-Ur-Rahman ◽  
Anees A. Siddiqui ◽  
Abuzer Ali ◽  
Mohammad Shahar Yar
Keyword(s):  
Benzimidazole Derivatives ◽  
Cox 2 ◽  
Cox 2 Inhibitors
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