Synthesis, biological evaluation, and molecular docking studies of novel chalcone oxime derivatives as potential tubulin polymerization inhibitors

RSC Advances ◽  
2014 ◽  
Vol 4 (61) ◽  
pp. 32263-32275 ◽  
Author(s):  
Yan-Ting Wang ◽  
Ya-Juan Qin ◽  
Ya-Liang Zhang ◽  
Yu-Jing Li ◽  
Bing Rao ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Cancer Cell ◽  
Inhibitory Activity ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Tubulin Polymerization ◽  
Molecular Docking Studies ◽  
Oxime Derivatives ◽  
Tubulin Polymerization Inhibitors

Compounds of novel chalcone oxime derivatives containing different substituent groups were designed, synthesized and evaluated for the inhibitory activity against tubulin polymerization and cancer cell inhibitory activity.

Synthesis, biological evaluation and molecular docking studies of novel 1,2,3-triazole-quinazolines as antiproliferative agents displaying ERK inhibitory activity

2021 ◽  
pp. 104982
Author(s):  
Paulo Sérgio Gonçalves Nunes ◽  
Gabriel da Silva ◽  
Sofia Nascimento ◽  
Susimaire Pedersoli Mantoani ◽  
Peterson de Andrade ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Inhibitory Activity ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Antiproliferative Agents ◽  
Molecular Docking Studies

Cycloplatinated(ii) complexes bearing 1,1′-bis(diphenylphosphino)ferrocene ligand: biological evaluation and molecular docking studies

2018 ◽  
Vol 42 (4) ◽  
pp. 2385-2392 ◽  
Author(s):  
Masood Fereidoonnezhad ◽  
Hamid R. Shahsavari ◽  
Sedigheh Abedanzadeh ◽  
Behnoosh Behchenari ◽  
Mojdeh Hossein-Abadi ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Cell Lines ◽  
Cancer Cell ◽  
Human Cancer ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Human Cancer Cell ◽  
Molecular Docking Studies ◽  
Human Cancer Cell Lines ◽  
High Cytotoxicity

Cycloplatinated(ii) complexes containing dppf ligand were prepared. These complexes exhibited high cytotoxicity and apoptosis-inducing activities to human cancer cell lines.

Molecular docking studies and biological evaluation of chalcone based pyrazolines as tyrosinase inhibitors and potential anticancer agents

RSC Advances ◽  
2015 ◽  
Vol 5 (57) ◽  
pp. 46330-46338 ◽  
Author(s):  
Hua-Li Qin ◽  
Zhen-Peng Shang ◽  
Ibrahim Jantan ◽  
Oya Unsal Tan ◽  
Muhammad Ajaz Hussain ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Anticancer Agents ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Tubulin Polymerization ◽  
Molecular Docking Studies ◽  
Tyrosinase Inhibitors

A series of synthetic chalcones and pyrazoline derivatives showed antityrosinase, anticancer and considerable tubulin polymerization activity.

Synthesis, biological evaluation and molecular docking studies of 1,3-benzoxazine derivatives as potential anticancer agents

2013 ◽  
Vol 22 (11) ◽  
pp. 5256-5266 ◽  
Author(s):  
Vikas Garg ◽  
Ankit Kumar ◽  
Anurag Chaudhary ◽  
Saurabh Agrawal ◽  
Praveen Tomar ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Anticancer Agents ◽  
Docking Studies ◽  
Biological Evaluation ◽  
Molecular Docking Studies
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